Search Results - "Kennedy, Malcolm W."
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Anisakis simplex: from Obscure Infectious Worm to Inducer of Immune Hypersensitivity
Published in Clinical Microbiology Reviews (01-04-2008)“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The house dust mite allergen Der p 5 binds lipid ligands and stimulates airway epithelial cells through a TLR2‐dependent pathway
Published in Clinical and experimental allergy (01-03-2019)“…Background Protein crystallographic studies suggest that the house dust mite (HDM) allergen Der p 5 potentially interacts with hydrophobic ligands. Der p 5, in…”
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3
Novel antiinflammatory biologics shaped by parasite-host coevolution
Published in Proceedings of the National Academy of Sciences - PNAS (06-09-2022)“…Parasitic helminth infections, while a major cause of neglected tropical disease burden, negatively correlate with the incidence of immune-mediated…”
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Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus
Published in Biochemical journal (01-11-2015)“…Fatty acid and retinol-binding proteins (FARs) comprise a family of unusual α-helix rich lipid-binding proteins found exclusively in nematodes. They are…”
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Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2
Published in Biophysical chemistry (01-07-2016)“…C60 fullerene is not soluble in water and dispersion usually requires organic solvents, sonication or vigorous mechanical mixing. However, we show here that…”
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Foam nest components of the túngara frog: a cocktail of proteins conferring physical and biological resilience
Published in Proceedings of the Royal Society. B, Biological sciences (22-05-2009)“…Engystomops pustulosus…”
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Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces
Published in Physical chemistry chemical physics : PCCP (22-03-2017)“…To stabilize foams, droplets and films at liquid interfaces a range of protein biosurfactants have evolved in nature. Compared to synthetic surfactants, these…”
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Latherin and other biocompatible surfactant proteins
Published in Biochemical Society transactions (01-08-2011)“…Horses and other equids are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active,…”
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Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils
Published in PLoS neglected tropical diseases (01-10-2018)“…Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from…”
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Atlantic Grey Seal Milk Shows Continuous Changes in Key Metabolites and Indicators of Metabolic Transition in Pups From Birth to Weaning
Published in Frontiers in Marine Science (11-01-2021)“…Mothers of the Atlantic grey seal, Halichoerus grypus , lactate for about 20 days, during which they do not feed and may have no access to water. Following…”
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Changes in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth--Three Phases in Early Lactation and Progressive Individual Differences
Published in PloS one (02-12-2015)“…Ursids (bears) in general, and giant pandas in particular, are highly altricial at birth. The components of bear milks and their changes with time may be…”
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Frog nest foams exhibit pharmaceutical foam-like properties
Published in Royal Society open science (08-09-2021)“…Foams have frequently been used as systems for the delivery of cosmetic and therapeutic molecules; however, there is high variability in the foamability and…”
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Latherin: A Surfactant Protein of Horse Sweat and Saliva
Published in PloS one (29-05-2009)“…Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated…”
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Identification and characterization of the major pseudocoelomic proteins of the giant kidney worm, Dioctophyme renale
Published in Parasites & vectors (27-09-2017)“…The giant kidney worm, Dioctophyme renale, is a debilitating and potentially lethal parasite that inhabits and destroys, typically host's right kidney, and may…”
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Buried treasure—marine turtles do not ‘disguise’ or ‘camouflage’ their nests but avoid them and create a decoy trail
Published in Royal Society open science (01-05-2020)“…After laying their eggs and refilling the egg chamber, sea turtles scatter sand extensively around the nest site. This is presumed to camouflage the nest, or…”
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Lipid-free antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties
Published in PLoS neglected tropical diseases (01-03-2015)“…The hydatid disease parasite Echinococcus granulosus has a restricted lipid metabolism, and needs to harvest essential lipids from the host. Antigen B (EgAgB),…”
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Correction to ‘Buried treasure—marine turtles do not “disguise” or “camouflage” their nests but avoid them and create a decoy trail’
Published in Royal Society open science (01-06-2020)Get full text
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Direct interaction between EgFABP1, a fatty acid binding protein from Echinococcus granulosus, and phospholipid membranes
Published in PLoS neglected tropical diseases (01-11-2012)“…Growth and maintenance of hydatid cysts produced by Echinococcus granulosus have a high requirement for host lipids for biosynthetic processes, membrane…”
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Allergen-specific IgE and IgG4 are markers of resistance and susceptibility in a human intestinal nematode infection
Published in Microbes and infection (01-06-2005)“…IgG4 has been proposed to act as a 'blocking antibody' due to its ability to compete for the same epitopes as IgE thus preventing IgE-dependent allergic…”
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Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation
Published in Royal Society open science (01-03-2017)“…Uterine secretory proteins protect the uterus and conceptuses against infection, facilitate implantation, control cellular damage resulting from implantation,…”
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