Search Results - "Kennedy, Lorna J"

Genetic diversity and population structure of African village dogs based on microsatellite and immunity-related molecular markers by Vychodilova, Leona, Necesankova, Michaela, Albrechtova, Katerina, Hlavac, Jan, Modry, David, Janova, Eva, Vyskocil, Mirko, Mihalca, Andrei D, Kennedy, Lorna J, Horin, Petr

“…The village and street dogs represent a unique model of canine populations. In the absence of selective breeding and veterinary care, they are subject mostly…”
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Factors influencing the antibody response of dogs vaccinated against rabies by Kennedy, Lorna J, Lunt, Mark, Barnes, Annette, McElhinney, Lorraine, Fooks, Anthony R, Baxter, David N, Ollier, William E.R

“…Abstract Since 2000, there has been a legal requirement in the UK that dogs and cats should have an effective rabies vaccination with demonstrable…”
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A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12 by Bianchi, Matteo, Dahlgren, Stina, Massey, Jonathan, Dietschi, Elisabeth, Kierczak, Marcin, Lund-Ziener, Martine, Sundberg, Katarina, Thoresen, Stein Istre, Kämpe, Olle, Andersson, Göran, Ollier, William E R, Hedhammar, Åke, Leeb, Tosso, Lindblad-Toh, Kerstin, Kennedy, Lorna J, Lingaas, Frode, Rosengren Pielberg, Gerli

“…Hypothyroidism is a complex clinical condition found in both humans and dogs, thought to be caused by a combination of genetic and environmental factors. In…”
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A selective sweep of >8 Mb on chromosome 26 in the Boxer genome by Quilez, Javier, Short, Andrea D, Martínez, Verónica, Kennedy, Lorna J, Ollier, William, Sanchez, Armand, Altet, Laura, Francino, Olga

“…Modern dog breeds display traits that are either breed-specific or shared by a few breeds as a result of genetic bottlenecks during the breed creation process…”
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Association of an MHC class II haplotype with increased risk of polymyositis in Hungarian Vizsla dogs by Massey, Jonathan, Rothwell, Simon, Rusbridge, Clare, Tauro, Anna, Addicott, Diane, Chinoy, Hector, Cooper, Robert G, Ollier, William E R, Kennedy, Lorna J

“…A breed-specific polymyositis is frequently observed in the Hungarian Vizsla. Beneficial clinical response to immunosuppressive therapies has been demonstrated…”
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Genetic control of canine leishmaniasis: genome-wide association study and genomic selection analysis by Quilez, Javier, Martínez, Verónica, Woolliams, John A, Sanchez, Armand, Pong-Wong, Ricardo, Kennedy, Lorna J, Quinnell, Rupert J, Ollier, William E R, Roura, Xavier, Ferrer, Lluís, Altet, Laura, Francino, Olga

“…The current disease model for leishmaniasis suggests that only a proportion of infected individuals develop clinical disease, while others are asymptomatically…”
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Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs by Tsai, Kate L., Starr-Moss, Alison N., Venkataraman, Gopalakrishnan M., Robinson, Christopher, Kennedy, Lorna J., Steiner, Jörg M., Clark, Leigh Anne

“…Exocrine pancreatic insufficiency (EPI) is a disease wherein pancreatic acinar cells fail to synthesize and secrete sufficient amounts of digestive enzymes for…”
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Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism by Boag, Alisdair M, Short, Andrea, Kennedy, Lorna J, Syme, Hattie, Graham, Peter A, Catchpole, Brian

“…Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison's disease in humans…”
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DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel by Bexfield, Nicholas H, Watson, Penny J, Aguirre-Hernandez, Jesús, Sargan, David R, Tiley, Laurence, Heeney, Jonathan L, Kennedy, Lorna J

“…Chronic hepatitis (CH) is common in dogs in the United Kingdom. An increased prevalence of the disease is seen in the English Springer spaniel (ESS), and this…”
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Impact of historical founder effects and a recent bottleneck on MHC variability in Commander Arctic foxes (Vulpes lagopus) by Ploshnitsa, Anna I., Goltsman, Mikhail E., Macdonald, David W., Kennedy, Lorna J., Sommer, Simone

“…Populations of Arctic foxes (Vulpes lagopus) have been isolated on two of the Commander Islands (Bering and Mednyi) from the circumpolar distributed mainland…”
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ISAG/IUIS-VIC Comparative MHC Nomenclature Committee report, 2005 by Ellis, Shirley A, Bontrop, Ronald E, Antczak, Doug F, Ballingall, Keith, Davies, Christopher J, Kaufman, Jim, Kennedy, Lorna J, Robinson, James, Smith, Douglas M, Stear, Michael J, Stet, Rene J M, Waller, Matthew J, Walter, Lutz, Marsh, Steven G E

“…Nomenclature for Major Histocompatibility Complex (MHC) genes and alleles in species other than humans and mice has historically been overseen either…”
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Dogslife: a web-based longitudinal study of Labrador Retriever health in the UK by Clements, Dylan N, Handel, Ian G, Rose, Erica, Querry, Damon, Pugh, Carys A, Ollier, William Er, Morgan, Kenton L, Kennedy, Lorna J, Sampson, Jeffery, Summers, Kim M, de Bronsvoort, B Mark C

“…Dogslife is the first large-scale internet-based longitudinal study of canine health. The study has been designed to examine how environmental and genetic…”
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Development and optimization of a hybridization technique to type the classical class I and class II B genes of the chicken MHC by Potts, Nicola D., Bichet, Coraline, Merat, Laurence, Guitton, Edouard, Krupa, Andrew P., Burke, Terry A., Kennedy, Lorna J., Sorci, Gabriele, Kaufman, Jim

“…The classical class I and class II molecules of the major histocompatibility complex (MHC) play crucial roles in immune responses to infectious pathogens and…”
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Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018 by Ballingall, Keith T., Bontrop, Ronald E., Ellis, Shirley A., Grimholt, Unni, Hammond, John A., Ho, Chak-Sum, Kaufman, Jim, Kennedy, Lorna J., Maccari, Giuseppe, Miller, Donald, Robinson, James, Marsh, Steven G. E.

“…Significant progress has been made over the last decade in defining major histocompatibility complex (MHC) diversity at the nucleotide, allele, haplotype,…”
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DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breeds by Gershony, Liza C, Belanger, Janelle M, Short, Andrea D, Le, Myly, Hytönen, Marjo K, Lohi, Hannes, Famula, Thomas R, Kennedy, Lorna J, Oberbauer, Anita M

“…Primary hypoadrenocorticism (Addison's disease, AD) and symmetrical lupoid onychodystrophy (SLO) are two clinical conditions with an autoimmune etiology that…”
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High Allelic Diversity of Dog Leukocyte Antigen Class II in East Asian Dogs: Identification of New Alleles and Haplotypes by Kang, Mingue, Ahn, Byeongyong, Youk, Seungyeon, Cho, Hye-sun, Choi, Munjeong, Hong, Kwonho, Do, Jeong Tae, Song, Hyuk, Jiang, Hao, Kennedy, Lorna J., Park, Chankyu

“…MHC genes are highly polymorphic as antigen presenting molecules for adaptive immune response in vertebrates. In this study, we evaluated the diversity of dog…”
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Breed differences in development of anti-insulin antibodies in diabetic dogs and investigation of the role of dog leukocyte antigen (DLA) genes by Holder, Angela L., Kennedy, Lorna J., Ollier, William E.R., Catchpole, Brian

“…Administration of insulin for treatment of diabetes mellitus in dogs can stimulate an immune response, with a proportion of animals developing anti-insulin…”
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Genetics of canine diabetes mellitus: Are the diabetes susceptibility genes identified in humans involved in breed susceptibility to diabetes mellitus in dogs? by Catchpole, Brian, Adams, Jamie P., Holder, Angela L., Short, Andrea D., Ollier, William E.R., Kennedy, Lorna J.

“…Diabetes mellitus is a common endocrinopathy in companion animals, characterised by hyperglycaemia, glycosuria and weight loss, resulting from an absolute or…”
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Single nucleotide polymorphisms in major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs by Peiravan, Atiyeh, Allenspach, Karin, Boag, Alisdair M., Soutter, Francesca, Holder, Angela, Catchpole, Brian, Kennedy, Lorna J., Werling, Dirk, Procoli, Fabio

“…•This study has identified an association between DLA-type and canine IBD.•The first protective (DLA-DRB1*015:02/DQA1*006:01/DQB1*023:01) DLA haplotypes for…”
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MYD88 and functionally related genes are associated with multiple infections in a model population of Kenyan village dogs by Necesankova, Michaela, Vychodilova, Leona, Albrechtova, Katerina, Kennedy, Lorna J., Hlavac, Jan, Sedlak, Kamil, Modry, David, Janova, Eva, Vyskocil, Mirko, Horin, Petr

“…The purpose of this study was to seek associations between immunity-related molecular markers and endemic infections in a model population of African village…”
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