Search Results - "Kennedy, Douglas R"

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    Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy by Ravin, Suk See Ting–De, Kennedy, Douglas R., Naumann, Nora, Kennedy, Jeffrey S., Choi, Uimook, Hartnett, Brian J., Linton, Gilda F., Whiting-Theobald, Narda L., Moore, Peter F., Vernau, William, Malech, Harry L., Felsburg, Peter J.

    Published in Blood (15-04-2006)
    “…X-linked severe combined immunodeficiency (XSCID) is characterized by profound immunodeficiency and early mortality, the only potential cure being…”
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    Journal Article
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    Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells by Swerdlow, Mathew P., Kennedy, Douglas R., Kennedy, Jeffrey S., Washabau, Robert J., Henthorn, Paula S., Moore, Peter F., Carding, Simon R., Felsburg, Peter J.

    Published in Veterinary Immunology and Immunopathology (15-12-2006)
    “…The gut maintains a delicate balance between the downregulation of inflammatory reactions to commensal bacteria and the capacity to respond to pathogens with…”
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    Intravenous injection of a foamy virus vector to correct canine SCID-X1 by Burtner, Christopher R., Beard, Brian C., Kennedy, Douglas R., Wohlfahrt, Martin E., Adair, Jennifer E., Trobridge, Grant D., Scharenberg, Andrew M., Torgerson, Troy R., Rawlings, David J., Felsburg, Peter J., Kiem, Hans-Peter

    Published in Blood (05-06-2014)
    “…Current approaches to hematopoietic stem cell (HSC) gene therapy involve the collection and ex vivo manipulation of HSCs, a process associated with loss of…”
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    Effect of Ex Vivo Culture of CD34+ Bone Marrow Cells on Immune Reconstitution of XSCID Dogs Following Allogeneic Bone Marrow Transplantation by Kennedy, Douglas R, McLellan, Kyle, Moore, Peter F, Henthorn, Paula S, Felsburg, Peter J

    “…Successful genetic treatment of most primary immunodeficiencies or hematological disorders will require the transduction of pluripotent, self-renewing…”
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    T Cell Repertoire Development in XSCID Dogs Following Nonconditioned Allogeneic Bone Marrow Transplantation by Vernau, William, Hartnett, Brian J, Kennedy, Douglas R, Moore, Peter F, Henthorn, Paula S, Weinberg, Kenneth I, Felsburg, Peter J

    “…Abstract Dogs with X-linked severe combined immunodeficiency (XSCID) can be successfully treated by bone marrow transplants (BMT) resulting in full immunologic…”
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    Improvement of Canine XSCID by In Vivo Gene Therapy Using RD114/TR-Pseudotyped SIV Lentiviral Vectors by Moayeri, Morvarid, De Ravin, Suk See, Kennedy, Douglas R., Naumann, Nora, Ikeda, Yasuhiro, Felsburg, Peter J., Malech, Harry L.

    Published in Blood (16-11-2006)
    “…X-linked severe combined immunodeficiency (XSCID) is characterized by profound immunodeficiency (dysfunctional B cells; absence of T and NK cells) and early…”
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    Journal Article
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    T Cell Repertoire Development in XSCID Dogs Following Non-conditioned Allogeneic Bone Marrow Transplantation by Vernau, William, Hartnett, Brian J., Kennedy, Douglas R., Moore, Peter F., Henthorn, Paula S., Weinberg, Kenneth I., Felsburg, Peter J.

    “…Dogs with X-linked severe combined immunodeficiency (XSCID) can be successfully treated by bone marrow transplants (BMT) resulting in full immunologic…”
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    Journal Article
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