Cognitive impairment and dementia in Parkinson's disease: a controlled study

The performance of 47 patients with Parkinson's disease on a battery of tests of cognition, motor function, disability and mood was compared with the performance of 47 healthy control subjects who were matched to the patients on the basis of age, sex and pre-morbid IQ. An increased prevalence o...

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Bibliographic Details
Published in:	Psychological medicine Vol. 21; no. 4; p. 911
Main Authors:	Boyd, J L, Cruickshank, C A, Kenn, C W, Madeley, P, Mindham, R H, Oswald, A G, Smith, R J, Spokes, E G
Format:	Journal Article
Language:	English
Published:	England 01-11-1991
Subjects:	Activities of Daily Living - psychology Affective Symptoms - diagnosis Affective Symptoms - psychology Aged Cognition Disorders - diagnosis Cognition Disorders - psychology Cohort Studies Dementia - diagnosis Dementia - psychology Female Humans Intelligence Male Middle Aged Neurologic Examination Neuropsychological Tests Parkinson Disease - diagnosis Parkinson Disease - psychology Wechsler Scales
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Summary:	The performance of 47 patients with Parkinson's disease on a battery of tests of cognition, motor function, disability and mood was compared with the performance of 47 healthy control subjects who were matched to the patients on the basis of age, sex and pre-morbid IQ. An increased prevalence of impairment over a range of cognitive functions was observed in the Parkinson's disease patients as compared with their matched controls. The differences between the Parkinson's disease patients and controls could not be accounted for by factors such as depressed mood, effects of medication or motor impairment. Our findings are discussed in relation to the methodology of previous studies in this area and to the need for a comprehensive clinico-pathological longitudinal study.
ISSN:	0033-2917
DOI:	10.1017/S0033291700029901