Search Results - "Kenichi FUNAMOTO"

Region-based SVD processing of high-frequency ultrafast ultrasound to visualize cutaneous vascular networks by Bhatti, Anam, Ishii, Takuro, Kanno, Naoya, Ikeda, Hayato, Funamoto, Kenichi, Saijo, Yoshifumi

“…•A novel region-based SVD filtering was devised to visualize skin micro-vasculature.•The imaging field was divided into two regions by identifying skin layers…”
Get full text

Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum by Cochet-Escartin, Olivier, Demircigil, Mete, Hirose, Satomi, Allais, Blandine, Gonzalo, Philippe, Mikaelian, Ivan, Funamoto, Kenichi, Anjard, Christophe, Calvez, Vincent, Rieu, Jean-Paul

“…Using a self-generated hypoxic assay, we show that the amoeba Dictyostelium discoideum displays a remarkable collective aerotactic behavior. When a cell colony…”
Get full text

Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers by Sone, Kazuki, Sakamaki, Yuka, Hirose, Satomi, Inagaki, Mai, Tachikawa, Masanori, Yoshino, Daisuke, Funamoto, Kenichi

“…Blood glucose levels fluctuate during daily life, and the oxygen concentration is low compared to the atmosphere. Vascular endothelial cells (ECs) maintain…”
Get full text

Numerical analysis of hemodynamic changes in the left atrium due to atrial fibrillation by Koizumi, Ryo, Funamoto, Kenichi, Hayase, Toshiyuki, Kanke, Yusuke, Shibata, Muneichi, Shiraishi, Yasuyuki, Yambe, Tomoyuki

“…Abstract Atrial fibrillation (AF) disrupts movement of the left atrium (LA) and worsens the vital prognosis by causing thromboembolism. Ultrasound Doppler…”
Get full text

Oxygen-dependent contraction and degradation of the extracellular matrix mediated by interaction between tumor and endothelial cells by Yoshino, Daisuke, Funamoto, Kenichi

“…Understanding the mechanisms of cancer development and metastasis requires comprehensive analyses of interactions between normal and tumor cells and the…”
Get full text

A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment by Funamoto, Kenichi, Zervantonakis, Ioannis K, Liu, Yuchun, Ochs, Christopher J, Kim, Choong, Kamm, Roger D

“…Low oxygen tensions experienced in various pathological and physiological conditions are a major stimulus for angiogenesis. Hypoxic conditions play a critical…”
Get more information

Microfluidic platform for the reproduction of hypoxic vascular microenvironments by Takahashi, Naoyuki, Yoshino, Daisuke, Sugahara, Ryuji, Hirose, Satomi, Sone, Kazuki, Rieu, Jean-Paul, Funamoto, Kenichi

“…Vascular endothelial cells (ECs) respond to mechanical stimuli caused by blood flow to maintain vascular homeostasis. Although the oxygen level in vascular…”
Get full text

Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice by Fushima, Tomofumi, Sekimoto, Akiyo, Minato, Takahiro, Ito, Takuya, Oe, Yuji, Kisu, Kiyomi, Sato, Emiko, Funamoto, Kenichi, Hayase, Toshiyuki, Kimura, Yoshitaka, Ito, Sadayoshi, Sato, Hiroshi, Takahashi, Nobuyuki

“…Preeclampsia (PE) is a pregnancy-induced hypertension with proteinuria that typically develops after 20 weeks of gestation. A reduction in uterine blood flow…”
Get full text

Hydrostatic pressure promotes endothelial tube formation through aquaporin 1 and Ras-ERK signaling by Yoshino, Daisuke, Funamoto, Kenichi, Sato, Kakeru, Kenry, Sato, Masaaki, Lim, Chwee Teck

“…Vascular tubulogenesis is tightly linked with physiological and pathological events in the living body. Endothelial cells (ECs), which are constantly exposed…”
Get full text

Development of Ultrasound Phantom Made of Transparent Material: Feasibility of Optical Particle Image Velocimetry by Hashuro, Muhammad Shiddiq Sayyid, Tupin, Simon, Putra, Narendra Kurnia, Daibo, Kotaro, Inoue, Kosuke, Ishii, Takuro, Kosukegawa, Hiroyuki, Funamoto, Kenichi, Hayase, Toshiyuki, Ohta, Makoto

“…The need for ultrasound flow phantoms to validate ultrasound systems requires the development of materials that can clearly visualize the flow inside for…”
Get full text

Local hemodynamics at the rupture point of cerebral aneurysms determined by computational fluid dynamics analysis by Omodaka, Shunsuke, Sugiyama, Shin-Ichirou, Inoue, Takashi, Funamoto, Kenichi, Fujimura, Miki, Shimizu, Hiroaki, Hayase, Toshiyuki, Takahashi, Akira, Tominaga, Teiji

“…Cerebral aneurysms carry a high risk of rupture and so present a major threat to the patient's life. Accurate criteria for predicting aneurysm rupture are…”
Get more information

Numerical analysis of hemodynamic changes and blood stagnation in the left ventricle by internal structures and torsional motion by Miyauchi, Suguru, Hosoi, Koichi, Tsuda, Shingo, Hayase, Toshiyuki, Funamoto, Kenichi

“…It is generally believed that thrombus formation does not occur in the left ventricle (LV) because of the high speed of blood flow. However, the LV has complex…”
Get full text

Numerical analysis of the blood flow in the left ventricle with internal structures: Effect of trabeculae carneae models and atrial fibrillation by Miyauchi, Suguru, Yamada, Tomomi, Hosoi, Koichi, Hayase, Toshiyuki, Funamoto, Kenichi

“…Internal structures of the inner wall of the left ventricle (LV), such as trabeculae carneae (TC) and papillary muscles, may reduce the blood flow velocity,…”
Get full text

Photoplethysmography and ultrasonic-measurement-integrated simulation to clarify the relation between two-dimensional unsteady blood flow field and forward and backward waves in a carotid artery by Sone, Shusaku, Hayase, Toshiyuki, Funamoto, Kenichi, Shirai, Atsushi

“…Understanding the spatiotemporal change in hemodynamics is essential for the basic research of atherosclerosis. The objective of this study was to establish a…”
Get full text

P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers by Hirose, Satomi, Tabata, Yugo, Sone, Kazuki, Takahashi, Naoyuki, Yoshino, Daisuke, Funamoto, Kenichi

“…The collective migration of vascular endothelial cells plays important roles in homeostasis and angiogenesis. Oxygen tension in vivo is a key factor affecting…”
Get full text

Study of Estimation Method for Unsteady Inflow Velocity in Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Simulation by Kadowaki, Hiroko, Hayase, Toshiyuki, Funamoto, Kenichi, Taniguchi, Nobuyuki

“…Information on hemodynamics is essential for elucidation of mechanisms and development of novel diagnostic methods for circulatory diseases. Two-dimensional…”
Get full text

Migration of vascular endothelial cells in monolayers under hypoxic exposure by Tabata, Yugo, Yoshino, Daisuke, Funamoto, Kiyoe, Koens, Rei, Kamm, Roger D, Funamoto, Kenichi

“…Abstract The hypoxic microenvironment existing in vivo is known to significantly affect cell morphology and dynamics, and cell group behaviour. Collective…”
Get full text

Model-based estimation of QT intervals of mouse fetal electrocardiogram by Widatalla, Namareq, Funamoto, Kiyoe, Kawataki, Motoyoshi, Yoshida, Chihiro, Funamoto, Kenichi, Saito, Masatoshi, Kasahara, Yoshiyuki, Khandoker, Ahsan, Kimura, Yoshitaka

“…Abstract Background Abnormal prolongation in the QT interval or long QT syndrome (LQTS) is associated with several cardiac complications such as sudden infant…”
Get full text

Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension by Koens, Rei, Tabata, Yugo, Serrano, Jean C., Aratake, Satoshi, Yoshino, Daisuke, Kamm, Roger D., Funamoto, Kenichi

“…Cells in a tumor microenvironment are exposed to spatial and temporal variations in oxygen tension due to hyperproliferation and immature vascularization. Such…”
Get full text

A Review of Functional Analysis of Endothelial Cells in Flow Chambers by Ohta, Makoto, Sakamoto, Naoya, Funamoto, Kenichi, Wang, Zi, Kojima, Yukiko, Anzai, Hitomi

“…The vascular endothelial cells constitute the innermost layer. The cells are exposed to mechanical stress by the flow, causing them to express their functions…”
Get full text