Search Results - "Kenessey, Istvan"

The characteristics of head and neck squamous cell cancer in young adults: A retrospective single-center study by Révész, Mónika, Oberna, Ferenc, Slezák, András, Ferenczi, Örs, Kenessey, István, Takácsi-Nagy, Zoltán

“…We aimed to characterize clinical and prognostical factors of primary head and neck squamous cell carcinoma (HNSCC) in 85 young patients (≤39 years, median…”
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Cancer Cell-Autonomous TRAIL-R Signaling Promotes KRAS-Driven Cancer Progression, Invasion, and Metastasis by von Karstedt, Silvia, Conti, Annalisa, Nobis, Max, Montinaro, Antonella, Hartwig, Torsten, Lemke, Johannes, Legler, Karen, Annewanter, Franka, Campbell, Andrew D., Taraborrelli, Lucia, Grosse-Wilde, Anne, Coy, Johannes F., El-Bahrawy, Mona A., Bergmann, Frank, Koschny, Ronald, Werner, Jens, Ganten, Tom M., Schweiger, Thomas, Hoetzenecker, Konrad, Kenessey, Istvan, Hegedüs, Balazs, Bergmann, Michael, Hauser, Charlotte, Egberts, Jan-Hendrik, Becker, Thomas, Röcken, Christoph, Kalthoff, Holger, Trauzold, Anna, Anderson, Kurt I., Sansom, Owen J., Walczak, Henning

“…Many cancers harbor oncogenic mutations of KRAS. Effectors mediating cancer progression, invasion, and metastasis in KRAS-mutated cancers are only incompletely…”
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Prognostic Ability of Tumor Budding Outperforms Poorly Differentiated Clusters in Gastric Cancer by Szalai, Luca, Jakab, Ákos, Kocsmár, Ildikó, Szirtes, Ildikó, Kenessey, István, Szijártó, Attila, Schaff, Zsuzsa, Kiss, András, Lotz, Gábor, Kocsmár, Éva

“…The prognostic value of histological phenomena tumor budding (TB) and poorly differentiated clusters (PDCs) have been less studied in gastric cancer (GAC) and…”
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Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer by Junttila, Anna, Helminen, Olli, Väyrynen, Juha P., Ahtiainen, Maarit, Kenessey, Istvan, Jalkanen, Sirpa, Mecklin, Jukka-Pekka, Kellokumpu, Ilmo, Kuopio, Teijo, Böhm, Jan, Mrena, Johanna

“…Background Immune response against cancer has prognostic impact but its role in gastric cancer is poorly known. The aim of the study was to assess the…”
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Comparison of Cancer Survival Trends in Hungary in the Periods 2001-2005 and 2011-2015 According to a Population-Based Cancer Registry by Kenessey, István, Szőke, Georgina, Dobozi, Mária, Szatmári, István, Wéber, András, Fogarassy, György, Nagy, Péter, Kásler, Miklós, Polgár, Csaba, Vathy-Fogarassy, Ágnes

“…Assessment of population-based cancer survival may provide the most valuable feedback about the effectiveness of oncological surveillance and treatment. Based…”
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The clinical impact of amino acid positron emission tomography measurements in the treatment of primary malignant brain tumors by Borbély, Katalin, Kenessey, István, Fedorcsák, Imre, Nagy, Dávid Gergő

“…Despite the large-scale diagnostic and therapeutic progress of recent years, the heterogeneity and therapeutic management of adult primary malignant brain…”
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A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1 by Farkas, Henriette, Máj, Csilla, Kenessey, István, Sebestyén, Anna, Krencz, Ildikó, Pápay, Judit, Cervenak, László

“…Abstract Background Hereditary angioedema (HAE) is a rare, life-threatening disease. The knowledge about the molecular pathogenesis of HAE has derived mainly…”
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The Role of Stereotactic Radiotherapy in the Management of Melanoma, A Retrospective Single Institute Preliminary Study of 30 Patients by Kispál, Mihály, Jánváry, Levente Zsolt, Balatoni, Tímea, Gábor, Stelczer, Fedorcsák, Imre, Katalin, Bőcs, Kenessey, István, Liszkay, Gabriella

“…Cutaneous melanoma is the third most common type of skin cancer in the world. The incidence of melanoma is increasing in most countries, however, mortality…”
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Changing Trends in Melanoma Incidence and Decreasing Melanoma Mortality in Hungary Between 2011 and 2019: A Nationwide Epidemiological Study by Liszkay, Gabriella, Kiss, Zoltan, Gyulai, Roland, Oláh, Judit, Holló, Péter, Emri, Gabriella, Csejtei, András, Kenessey, István, Benedek, Angela, Polányi, Zoltán, Nagy-Erdei, Zsófia, Daniel, Andrea, Knollmajer, Kata, Várnai, Máté, Vokó, Zoltán, Nagy, Balázs, Rokszin, György, Fábián, Ibolya, Barcza, Zsófia, Polgár, Csaba

“…The incidence of malignant melanoma has continually increased during the past few decades, however, certain reports suggest a recent change in trends. The aim…”
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Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer by Tahkola, Kyösti, Ahtiainen, Maarit, Kellokumpu, Ilmo, Mecklin, Jukka-Pekka, Laukkarinen, Johanna, Laakkonen, Joni, Kenessey, Istvan, Jalkanen, Sirpa, Salmi, Marko, Böhm, Jan

“…Immune suppressing molecule CD73 is overexpressed in various cancers and associated with poor survival. Little is so far known about the predictive value of…”
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Local Invasion Patterns Characterized by SARIFA and Tumor Budding Differ and Have Distinct Prognostic Significance in Esophageal Adenocarcinoma and Squamous Cell Carcinoma by Jakab, Ákos, Zarándy, Levente, Kocsmár, Ildikó, Várkonyi, Tibor, Kenessey, István, Szijártó, Attila, Kiss, András, Vass, Tamás, Lotz, Gábor, Kocsmár, Éva

“…Both esophageal squamous cell carcinoma (ESQCC) and adenocarcinoma (EAC) are known to have poor prognosis. We aimed to investigate the invasion front areas of…”
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Isoprostanes evoke contraction of the murine and human detrusor muscle via activation of the thromboxane prostanoid TP receptor and Rho kinase by Molnár, Péter József, Dér, Bálint, Borsodi, Kinga, Balla, Helga, Borbás, Zsófia, Molnár, Krisztina, Ruisanchez, Éva, Kenessey, István, Horváth, András, Keszthelyi, Attila, Majoros, Attila, Nyirády, Péter, Offermanns, Stefan, Benyó, Zoltán

“…Local or systemic inflammation can severely impair urinary bladder functions and contribute to the development of voiding disorders in millions of people…”
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Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells by Garay, Tamás, Kenessey, István, Molnár, Eszter, Juhász, Éva, Réti, Andrea, László, Viktória, Rózsás, Anita, Dobos, Judit, Döme, Balázs, Berger, Walter, Klepetko, Walter, Tóvári, József, Tímár, József, Hegedűs, Balázs

“…While targeted therapy brought a new era in the treatment of BRAF mutant melanoma, therapeutic options for non-BRAF mutant cases are still limited. In order to…”
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Improving Quality Indicator of Melanoma Management - Change of Melanoma Mortality-to-Incidence Rate Ratio Based on a Hungarian Nationwide Retrospective Study by Várnai, Máté, Kiss, Zoltán, Gyulai, Rolland, Oláh, Judit, Holló, Péter, Emri, Gabriella, Csejtei, András, Kenessey, István, Benedek, Angéla, Polányi, Zoltán, Nagy-Erdei, Zsófia, Dániel, Andrea, Knollmajer, Kata, Rokszin, György, Fábián, Ibolya, Barcza, Zsófia, Polgár, Csaba, Nagy, Balázs, Liszkay, Gabriella, Vokó, Zoltán

“…The incidence of melanoma has been increasing in the last decades. A retrospective Hungarian epidemiological study provided real-world data on incidence and…”
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Comparison of Hungarian Central Statistical Office's causes of death data with the database of the Hungarian National Cancer Registry by Wéber, András, Szatmári, István, Dobozi, Mária, Hilbert, Lászlóné, Branyiczkiné Géczy, Gabriella, Nagy, Péter, Kásler, Miklós, Polgár, Csaba, Kenessey, István

“…Introduction: In international comparison, Hungary is in the forefront of cancer incidence and mortality statistics. Based on paper-based death certificates,…”
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Therapeutic and Adverse Effect of Anti-PD1 Immunotherapy in Melanoma: A Retrospective, Single-Institute Study of 222 Patients by Eikenes, Grethe, Liszkay, Gabriella, Balatoni, Tímea, Czirbesz, Kata, Hunyadi, Karen, Kozéki, Zsófia, Kispál, Mihály Tamás, Baranyai, Fanni, Danyi, Tímea, Bőcs, Katalin, Kenessey, István

“…The introduction of immuno- and targeted therapeutic modalities meant a breakthrough step in the therapy of melanoma. As a checkpoint inhibitor, the more…”
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Apelin expression in human non-small cell lung cancer: role in angiogenesis and prognosis by Berta, Judit, Kenessey, Istvan, Dobos, Judit, Tovari, Jozsef, Klepetko, Walter, Jan Ankersmit, Hendrik, Hegedus, Balazs, Renyi-Vamos, Ferenc, Varga, Janos, Lorincz, Zsolt, Paku, Sandor, Ostoros, Gyula, Rozsas, Anita, Timar, Jozsef, Dome, Balazs

“…The recently discovered bioactive peptide, apelin, has been demonstrated to stimulate angiogenesis in various experimental systems. However, its clinical…”
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Mammalian target of rapamycin (mTOR) activity dependent phospho-protein expression in childhood acute lymphoblastic leukemia (ALL) by Nemes, Karolina, Sebestyén, Anna, Márk, Agnes, Hajdu, Melinda, Kenessey, István, Sticz, Tamás, Nagy, Eszter, Barna, Gábor, Váradi, Zsófia, Kovács, Gábor, Kopper, László, Csóka, Monika

“…Modern treatment strategies have improved the prognosis of childhood ALL; however, treatment still fails in 25-30% of patients. Further improvement of…”
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Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK by Hegedüs, Luca, Padányi, Rita, Molnár, Judit, Pászty, Katalin, Varga, Karolina, Kenessey, István, Sárközy, Eszter, Wolf, Matthias, Grusch, Michael, Hegyi, Zoltán, Homolya, László, Aigner, Clemens, Garay, Tamás, Hegedüs, Balázs, Tímár, József, Kállay, Enikö, Enyedi, Ágnes

“…Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients…”
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Identification and clinical significance of circulating endothelial progenitor cells in human non-small cell lung cancer by DOME, Balazs, TIMAR, Jozsef, BOGOS, Krisztina, TOVARI, Jozsef, DOBOS, Judit, MESZAROS, Livia, RASO, Erzsebet, PAKU, Sandor, KENESSEY, Istvan, OSTOROS, Gyula, MAGYAR, Melinda, LADANYI, Andrea

“…Until recently, it was generally accepted that vascularization of tumors arises exclusively from endothelial sprouting. Whether circulating bone marrow-derived…”
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