Search Results - "Kendall, David M"
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Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study
Published in The Lancet (British edition) (04-10-2008)“…Summary Background Exenatide is an incretin mimetic that shares glucoregulatory properties with glucagon-like peptide 1 (GLP-1), and improves glycaemic…”
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Dasiglucagon for the Treatment of Congenital Hyperinsulinism: A Randomized Phase 3 Trial in Infants and Children
Published in The journal of clinical endocrinology and metabolism (15-03-2024)“…Abstract Context Congenital hyperinsulinism (CHI) is characterized by dysregulated insulin secretion causing hypoglycemia and consequent brain damage…”
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Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families
Published in Orphanet journal of rare diseases (19-02-2022)“…Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infants and children, and carries a considerable risk of neurological…”
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Effects of Exenatide (Exendin-4) on Glycemic Control Over 30 Weeks in Patients With Type 2 Diabetes Treated With Metformin and a Sulfonylurea
Published in Diabetes care (01-05-2005)“…OBJECTIVE:--This study evaluated the effects of exenatide, a novel incretin mimetic, in hyperglycemic patients with type 2 diabetes unable to achieve glycemic…”
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Clinical Application of Incretin-Based Therapy: Therapeutic Potential, Patient Selection and Clinical Use
Published in The American journal of medicine (01-06-2009)“…Abstract Incretin-based therapies address the progressive nature of type 2 diabetes mellitus, not only by addressing glucose control but also with…”
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Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: A multinational, randomized, open-label, two-period, crossover noninferiority trial
Published in Clinical therapeutics (01-11-2007)“…Abstract Objective: This study was conducted to compare the efficacy and safety profiles of exenatide and insulin glargine therapy in patients with type 2…”
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Comparison of Lipid and Glycemic Effects of Pioglitazone and Rosiglitazone in Patients With Type 2 Diabetes and Dyslipidemia
Published in Diabetes care (01-07-2005)“…OBJECTIVE:--Published reports suggest that pioglitazone and rosiglitazone have different effects on lipids in patients with type 2 diabetes. However, these…”
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Correction to: Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families
Published in Orphanet journal of rare diseases (18-05-2022)“…Congenital hyperinsulinism (CHI) is a rare disease that causes newborn babies and children to have low blood sugar because of the abnormal release of insulin…”
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Pioglitazone and Rosiglitazone Have Different Effects on Serum Lipoprotein Particle Concentrations and Sizes in Patients With Type 2 Diabetes and Dyslipidemia
Published in Diabetes care (01-10-2007)“…OBJECTIVE:--Associated with insulin resistance in type 2 diabetes are increased serum triglycerides, decreased HDL cholesterol, and a predominance of large…”
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Glycemia Treatment Strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial
Published in The American journal of cardiology (18-06-2007)“…There is an independent progressive epidemiologic relation between glycemia and cardiovascular disease (CVD) events; however, whether lowering glucose levels…”
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Type 2 Diabetes: Assessing the Relative Risks and Benefits of Glucose-lowering Medications
Published in The American journal of medicine (01-04-2010)“…Abstract The selection of appropriate pharmacologic therapy for any disease requires a careful assessment of benefit and risk. In the case of type 2 diabetes,…”
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Associations Between Glycemic Control, Depressed Mood, Clinical Depression, and Diabetes Distress Before and After Insulin Initiation: An Exploratory, Post Hoc Analysis
Published in Diabetes therapy (01-09-2015)“…Introduction Although depression is often associated with poor glycemic control in patients with type 2 diabetes mellitus (T2DM), this observation has been…”
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Clinical Application of Incretin-Based Therapy: Therapeutic Potential, Patient Selection and Clinical Use
Published in European journal of internal medicine (01-07-2009)“…Abstract Incretin-based therapies address the progressive nature of type 2 diabetes mellitus, not only by addressing glucose control but also with…”
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Early Glycemic Response Predicts Achievement of Subsequent Treatment Targets in the Treatment of Type 2 Diabetes: A Post hoc Analysis
Published in Diabetes therapy (01-09-2015)“…Introduction American Diabetes Association consensus guidelines emphasize individualized treatment in the management of type 2 diabetes mellitus (T2DM). Early…”
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A Comparative Study of Dasiglucagon Ready-to-Use Autoinjector and Glucagon Emergency Kit During Rescue from Simulated Severe Hypoglycemia
Published in Diabetes technology & therapeutics (01-04-2022)“…Severe hypoglycemic episodes are life-threatening events demanding rapid administration of glucagon by a caregiver or bystander. The glucagon analog…”
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Prevention of Diabetes for up to 13 Years by Autoislet Transplantation After Pancreatectomy for Chronic Pancreatitis
Published in Diabetes (New York, N.Y.) (01-01-2001)“…Prevention of Diabetes for up to 13 Years by Autoislet Transplantation After Pancreatectomy for Chronic Pancreatitis R. Paul Robertson , Karla J. Lanz , David…”
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1024-P: Technosphere Insulin Added to Basal Insulin Is Associated with Less Weight Gain than Basal Insulin plus Insulin Aspart or Insulin Analog (Aspart) 70/30 Mixture in Type 2 DM
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Technosphere Insulin (TI) is a dry-powder formulation of recombinant human insulin adsorbed onto Technosphere microparticles for oral inhalation. Data from two…”
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137-OR: Dasiglucagon Ready-to-Use Autoinjector Is More Reliably and Quickly Administered than Glucagon Emergency Kit (GEK)
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Dasiglucagon is a novel glucagon analog, stable in aqueous solution and suitable for delivery in a ready-to-use autoinjector (HypoPal®) for the treatment of…”
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One-Year Treatment With Exenatide Improves β-Cell Function, Compared With Insulin Glargine, in Metformin-Treated Type 2 Diabetic Patients: A randomized, controlled trial
Published in Diabetes care (01-05-2009)“…OBJECTIVE: Traditional blood glucose-lowering agents do not sustain adequate glycemic control in most type 2 diabetic patients. Preclinical studies with…”
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RESULTS OF A 24-WEEK TRIAL OF TECHNOSPHERE INSULIN VERSUS INSULIN ASPART IN TYPE 2 DIABETES
Published in Endocrine practice (01-01-2021)“…To compare glycemic efficacy of Technosphere insulin (TI) versus that of insulin aspart (IA), each added to basal insulin, in type 2 diabetes. This randomized,…”
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