Search Results - "Kench, Jennifer A"

Interaction between Phosphatidylserine and the Phosphatidylserine Receptor Inhibits Immune Responses In Vivo by Hoffmann, Peter R, Kench, Jennifer A, Vondracek, Andrea, Kruk, Ellen, Daleke, David L, Jordan, Michael, Marrack, Philippa, Henson, Peter M, Fadok, Valerie A

“…Phosphatidylserine (PS) on apoptotic cells promotes their uptake and induces anti-inflammatory responses in phagocytes, including TGF-beta release. Little is…”
Get full text

Lovastatin Enhances Clearance of Apoptotic Cells (Efferocytosis) with Implications for Chronic Obstructive Pulmonary Disease by Morimoto, Konosuke, Janssen, William J, Fessler, Michael B, McPhillips, Kathleen A, Borges, Valeria M, Bowler, Russell P, Xiao, Yi-Qun, Kench, Jennifer A, Henson, Peter M, Vandivier, R. William

“…Statins are potent, cholesterol-lowering agents with newly appreciated, broad anti-inflammatory properties, largely based upon their ability to block the…”
Get full text

General parity between trio and pairwise breeding of laboratory mice in static caging by Kedl, Ross M, Wysocki, Lawrence J, Janssen, William J, Born, Willi K, Rosenbaum, Matthew D, Granowski, Julia, Kench, Jennifer A, Fong, Derek L, Switzer, Lisa A, Cruse, Margaret, Huang, Hua, Jakubzick, Claudia V, Kosmider, Beata, Takeda, Katsuyuki, Stranova, Thomas J, Klumm, Randal C, Delgado, Christine, Tummala, Saigiridhar, De Langhe, Stijn, Cambier, John, Haskins, Katherine, Lenz, Laurel L, Curran-Everett, Douglas

“…Changes made in the 8th edition of the Guide for the Care and Use of Laboratory Animals included new recommendations for the amount of space for breeding…”
Get full text

Statins enhance clearance of apoptotic cells through modulation of Rho-GTPases by Morimoto, Konosuke, Janssen, William J, Fessler, Michael B, Xiao, Yi Qun, McPhillips, Kathleen A, Borges, Valeria M, Kench, Jennifer A, Henson, Peter M, Vandivier, R William

Get full text

A functional B cell receptor transgene allows efficient IL-7- independent maturation of B cell precursors by Melamed, D, Kench, JA, Grabstein, K, Rolink, A, Nemazee, D

“…IL-7 supports the proliferation of B cell precursors, but inhibits their maturation to mature surface IgM+ (sIgM+) B cells. This inhibition is thought to occur…”
Get full text

Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes by Kench, J A, Russell, D M, Nemazee, D

“…Peripheral B cell tolerance was studied in mice of the autoimmune-prone, Fas-deficient MRL/ lpr.H-2(d) genetic background by introducing a transgene that…”
Get full text

Aberrant Wound Healing and TGF-β Production in the Autoimmune-Prone MRL/+ Mouse by Kench, Jennifer A., Russell, David M., Fadok, Valerie A., Young, Scott K., Worthen, G.Scott, Jones-Carson, Jessica, Henson, Janet E., Henson, Peter M., Nemazee, David

“…Wound healing is a complex process that involves inflammation, apoptosis, growth, and tissue remodeling. The autoimmune-prone inbred mouse strain MRL/+…”
Get full text

TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation by Borges, Valeria M, Vandivier, R William, McPhillips, Kathleen A, Kench, Jennifer A, Morimoto, Konosuke, Groshong, Steve D, Richens, Tiffany R, Graham, Brian B, Muldrow, Alaina M, Van Heule, Lea, Henson, Peter M, Janssen, William J

“…Efficient removal of apoptotic cells is essential for resolution of inflammation. Failure to clear dying cells can exacerbate lung injury and lead to…”
Get more information