Search Results - "Kenanova, Vania E."

Unexpected Expression Pattern for Glycosylphosphatidylinositol-anchored HDL-binding Protein 1 (GPIHBP1) in Mouse Tissues Revealed by Positron Emission Tomography Scanning by Olafsen, Tove, Young, Stephen G., Davies, Brandon S.J., Beigneux, Anne P., Kenanova, Vania E., Voss, Constance, Young, Glen, Wong, Koon-Pong, Barnes, Richard H., Tu, Yiping, Weinstein, Michael M., Nobumori, Chika, Huang, Sung-Cheng, Goldberg, Ira J., Bensadoun, André, Wu, Anna M., Fong, Loren G.

“…Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1), a GPI-anchored endothelial cell protein, binds lipoprotein lipase…”
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Recombinant Anti-CD20 Antibody Fragments for Small-Animal PET Imaging of B-Cell Lymphomas by Olafsen, Tove, Betting, David, Kenanova, Vania E, Salazar, Felix B, Clarke, Pat, Said, Jonathan, Raubitschek, Andrew A, Timmerman, John M, Wu, Anna M

“…The CD20 cell surface antigen is expressed at high levels by over 90% of B-cell non-Hodgkin lymphomas (NHL) and is the target of the anti-CD20 monoclonal…”
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Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life by Andersen, Jan Terje, Foss, Stian, Kenanova, Vania E., Olafsen, Tove, Leikfoss, Ingvild S., Roopenian, Derry C., Wu, Anna M., Sandlie, Inger

“…Serum half-life of IgG is controlled by the neonatal Fc receptor (FcRn) that interacts with the IgG Fc region and may be increased or decreased as a function…”
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Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment by Olafsen, Tove, Kenanova, Vania E, Wu, Anna M

“…Immunoglobulins (Igs) are large proteins of 150 kDa with prolonged residence time in blood. Their half-life is controlled by their ability to interact with the…”
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Tuning the serum persistence of human serum albumin domain III:diabody fusion proteins by Kenanova, Vania E., Olafsen, Tove, Salazar, Felix B., Williams, Lawrence E., Knowles, Scott, Wu, Anna M.

“…The long circulation persistence of human serum albumin (HSA) is enabled by its domain III (DIII) interaction with the neonatal Fc receptor (FcRn). A protein…”
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Evaluation of Two Internalizing Carcinoembryonic Antigen Reporter Genes for Molecular Imaging by Barat, Bhaswati, Kenanova, Vania E., Olafsen, Tove, Wu, Anna M.

“…Purpose The objective of this article is to develop internalizing positron emission tomography (PET) reporter genes for tracking genetically modified T cells…”
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Numerical comparison of iodine-based and indium-based antibody biodistributions by Williams, Lawrence E, Wu, Anna M, Kenanova, Vania E, Olafsen, Tove, Yazaki, Paul J

“…Single-step iodination is often performed in preference to use of a radiometal label for initial animal biodistributions. Yet loss of iodine occurs in vivo so…”
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Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues by Andersen, Jan T, Justesen, Sune, Fleckenstein, Burkhard, Michaelsen, Terje E, Berntzen, Gøril, Kenanova, Vania E, Daba, Muluneh B, Lauvrak, Vigdis, Buus, Søren, Sandlie, Inger

“…The neonatal Fc receptor (FcRn) is a major histocompatibility complex class I-related molecule that regulates the half-life of IgG and albumin. In addition,…”
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A differential cell capture assay for evaluating antibody interactions with cell surface targets by Sherman, David J., Kenanova, Vania E., Lepin, Eric J., McCabe, Katelyn E., Kamei, Ken-ichiro, Ohashi, Minori, Wang, Shutao, Tseng, Hsian-Rong, Wu, Anna M., Behrenbruch, Christian P.

“…Many biological and biomedical laboratory assays require the use of antibodies and antibody fragments that strongly bind to their cell surface targets…”
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ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies) by Olafsen, Tove, Sirk, Shannon J., Betting, David J., Kenanova, Vania E., Bauer, Karl B., Ladno, Waldemar, Raubitschek, Andrew A., Timmerman, John M., Wu, Anna M.

“…Rapid clearing engineered antibody fragments for immunoPET promise high sensitivity at early time points. Here, tumor targeting of anti-CD20 diabodies (scFv…”
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Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging by OLAFSEN, Tove, KENANOVA, Vania E, WONG, Jeffrey Y. C, RAUBITSCHEK, Andrew A, SHIVELY, John E, WU, Anna M, SUNDARESAN, Gobalakrishnan, ANDERSON, Anne-Line, CROW, Desiree, YAZAKI, Paul J, LIN LI, PRESS, Michael F, GAMBHIR, Sanjiv S, WILLIAMS, Lawrence E

“…We have recently described the in vivo properties of an iodinated anti-p185HER2 engineered antibody fragment [minibody (scFv-C(H)3)2; 80 kDa], made from the…”
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Recombinant anti-CD20 antibody fragments for microPET imaging of B-cell lymphoma by Olafsen, Tove, Betting, David, Kenanova, Vania E., Salazar, Felix B., Clarke, Pat, Said, Jonathan, Raubitschek, Andrew A., Timmerman, John M., Wu, Anna M.

“…The CD20 cell surface antigen is expressed at high levels by over 90% of B cell non-Hodgkin lymphomas (NHL), and is the target of the anti-CD20 monoclonal…”
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ImmunoPET imaging of B-cell lymphoma using super(124)I-anti-CD20 scFv dimers (diabodies) by Olafsen, Tove, Sirk, Shannon J, Betting, David J, Kenanova, Vania E, Bauer, Karl B, Ladno, Waldemar, Raubitschek, Andrew A, Timmerman, John M, Wu, Anna M

“…Rapid clearing engineered antibody fragments for immunoPET promise high sensitivity at early time points. Here, tumor targeting of anti-CD20 diabodies (scFv…”
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Optimizing Radiolabeled Engineered Anti-p185 super(HER2) Antibody Fragments for In vivo Imaging by Olafsen, Tove, Kenanova, Vania E, Sundaresan, Gobalakrishnan, Anderson, Anne-Line, Crow, Desiree, Yazaki, Paul J, Li, Lin, Press, Michael F, Gambhir, Sanjiv S, Williams, Lawrence E, Wong, Jeffrey YC, Raubitschek, Andrew A, Shively, John E, Wu, Anna M

“…We have recently described the in vivo properties of an iodinated anti-p185 super(HER2) engineered antibody fragment [minibody (scFv-C sub(H)3) sub(2); 80…”
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Tuning the serum persistence of human serum albumin domain III:diabody fusion proteins by Kenanova, Vania E, Olafsen, Tove, Salazar, Felix B, Williams, Lawrence E, Knowles, Scott, Wu, Anna M

“…The long circulation persistence of human serum albumin (HSA) is enabled by its domain III (DIII) interaction with the neonatal Fc receptor (FcRn). A protein…”
Get full text