Search Results - "Kemppainen, Robert"

The Herbicide Atrazine Potentiates Angiotensin II-Induced Aldosterone Synthesis and Release From Adrenal Cells by Zimmerman, Arthur D, Mackay, Laci, Kemppainen, Robert J, Jones, Melaney A, Read, Casey C, Schwartz, Dean, Foradori, Chad D

“…Atrazine is one of the most commonly used pre-emergence and early post-emergence herbicides in the world. We have shown previously that atrazine does not…”
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Low‐dose ACTH stimulation testing in dogs suspected of hypoadrenocorticism by Botsford, Annabel, Behrend, Ellen N., Kemppainen, Robert J., Gaillard, Philippe R., Oprandy, Frank, Lee, Hollie P.

“…Background Low‐dose ACTH stimulation testing would lower cost and may increase sensitivity for identification of partial ACTH deficiency. Hypothesis (1) The…”
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Effect of EDTA on measurement of cortisol and thyroxine by chemiluminescent enzyme immunoassay in dogs by Schechter, Dana A., Lee, Hollie P., Kemppainen, Robert J., Behrend, Ellen N.

“…The addition of ethylenediamine tetra-acetic acid (EDTA) to serum can affect the measurement of cortisol by chemiluminescent enzyme immunoassay (CEIA);…”
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Amino acid differences in cat adrenocorticotropin account for the inability of a human-based immunoradiometric assay to detect the molecule in cat plasma by Kemppainen, Robert J.

“…A commercial immunoradiometric assay kit designed for the measurement of endogenous adrenocorticotropin (ACTH) concentrations in human plasma does not detect…”
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Inoculation of dogs with a recombinant ACTH vaccine by Kemppainen, Robert J

“…To determine whether inoculation of healthy dogs with a recombinant peptide containing 3 copies of ACTH would result in the production of antibodies against…”
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Characterization of Activation of the Hypothalamic-Pituitary-Adrenal Axis by the Herbicide Atrazine in the Female Rat by Foradori, Chad D, Healy, Jessica E, Zimmerman, Arthur D, Kemppainen, Robert J, Jones, Melaney A, Read, Casey C, White, B Douglas, Yi, Kun Don, Hinds, Laura R, Lacagnina, Anthony F, Quihuis, Alicia M, Breckenridge, Charles B, Handa, Robert J

“…Atrazine (ATR) is a commonly used pre-emergence and early postemergence herbicide. Rats gavaged with ATR and its chlorometabolites desethylatrazine (DEA) and…”
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Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration by Ramesh Babu, J, Lamar Seibenhener, M, Peng, Junmin, Strom, Anna-Lena, Kemppainen, Robert, Cox, Nancy, Zhu, Haining, Wooten, Michael C, Diaz-Meco, María T, Moscat, Jorge, Wooten, Marie W

“…The signaling adapter p62 plays a coordinating role in mediating phosphorylation and ubiquitin-dependent trafficking of interacting proteins. However, there is…”
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Iodine speciation in dog foods and treats by high performance liquid chromatography with inductively coupled plasma mass spectrometry detection by Wilson, Robert A., Yanes, Enrique G., Kemppainen, Robert J.

“…•Developed a LC-ICP-MS method for quantification of thyroid hormones in dog jerky.•Multiple dog foods and treats were analyzed following an enzymatic…”
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Excess EDTA interferes with cortisol measurement using a solid-phase, chemiluminescent enzyme immunoassay by Kemppainen, Robert J., Behrend, Ellen N., Carter, Stephanie F., Cole, Janeva E.

“…Hormone assays that use a solid-phase, automated, chemiluminescent enzyme immunoassay (CEIA) with an alkaline phosphatase–tagged hormone or antibody as a…”
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Effect of laparotomy on the pituitary-adrenal axis in dogs by Skovira, Emily J, Behrend, Ellen N, Martin, Linda G, Palmer, Lee E, Kemppainen, Robert J, Lee, Hollie P

“…OBJECTIVE To assess effects of major abdominal surgery on serum cortisol and aldosterone and plasma canine ACTH (cACTH) concentrations. ANIMALS 39 healthy dogs…”
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Pet Food-Associated Dietary Exogenous Thyrotoxicosis: Retrospective Study (2016-2018) and Clinical Considerations by Rotstein, David, Jones, Jennifer L., Buchweitz, John, Refsal, Kent R., Wilson, Robert, Yanes, Enrique G., Heitkemper, Doug, Edwards, Elizabeth, Post, Lynn, Palmer, Lee Anne, Carey, Lauren, Wolf, Krisztina, Burkholder, William, Ceric, Olgica, Glover, Mark, Hodges, April, Kemppainen, Robert J, Lambkin, Sonya, Lovell, Randall, Nemser, Sarah, Wilkinson, Caroline, Reimschuessel, Renate

“…Dietary exogenous thyrotoxicosis is infrequently observed in pet food. A retrospective evaluation of pet food investigations (PFI) was conducted for 17 dogs,…”
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Exogenous thyrotoxicosis in dogs attributable to consumption of all-meat commercial dog food or treats containing excessive thyroid hormone: 14 cases (2008–2013) by Broome, Michael R, Peterson, Mark E, Kemppainen, Robert J, Parker, Valerie J, Richter, Keith P

“…Objective-To describe findings in dogs with exogenous thyrotoxicosis attributable to consumption of commercially available dog foods or treats containing high…”
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Seasonal variation in results of diagnostic tests for pituitary pars intermedia dysfunction in older, clinically normal geldings by Schreiber, Christopher M, Stewart, Allison J, Kwessi, Eddy, Behrend, Ellen N, Wright, James C, Kemppainen, Robert J, Busch, Katherine A

“…To determine whether seasonal variations exist in endogenous plasma ACTH, plasma α-melanocyte-stimulating hormone (α-MSH), serum cortisol, and serum insulin…”
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Acute inhibition of carboxypeptidase E expression in AtT-20 cells does not affect regulated secretion of ACTH by Kemppainen, Robert J., Behrend, Ellen N.

“…Carboxypeptidase E (CPE) is an exopeptidase that removes C-terminal basic amino acids from a variety of bioactive peptides. In addition to this role, data…”
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Validation of a low-dose adrenocorticotropic hormone stimulation test in healthy neonatal foals by Stewart, Allsion J, Wright, James C, Behrend, Ellen N, Martin, Linda G, Kemppainen, Robert J, Busch, Katherine A

“…Objective-To determine the lowest ACTH dose that would induce a significant increase in serum cortisol concentration and identify the time to peak cortisol…”
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Prenylated Rab acceptor domain family member 1 is involved in stimulated ACTH secretion and inhibition by Compton, Shannon L., Kemppainen, Robert J., Behrend, Ellen N.

“…Dexamethasone (Dex) inhibits stimulated adrenocorticotrophic hormone (ACTH) secretion in AtT-20 cells, a mouse corticotroph tumor cell line. Dexras1 protein…”
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Validation of a low-dose ACTH stimulation test in healthy adult horses by Stewart, Allison J, Behrend, Ellen N, Wright, James C, Martin, Linda G, Kemppainen, Robert J, Busch, Katherine A, Hanson, R. Reid

“…Objective—To determine the lowest ACTH dose that would induce a maximum increase in serum cortisol concentration in healthy adult horses and identify the time…”
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Pituitary-adrenal function in dogs with acute critical illness by Martin, L.G, Groman, R.P, Fletcher, D.J, Behrend, E.N, Kemppainen, R.J, Moser, V.R, Hickey, K.C

“…To evaluate pituitary-adrenal function in critically ill dogs with sepsis, severe trauma, and gastric dilatation-volvulus (GDV). Cohort study. 31 ill dogs…”
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Comparative analysis of Xenopus tropicalis hepcidin I and hepcidin II genes by Hu, Xueyou, Ward, Chelsea, Aono, Shelly, Lan, Liqiong, Dykstra, Christine, Kemppainen, Robert J., Morrison, Edward E., Shi, Jishu

“…Hepcidin is an antimicrobial peptide and an iron-regulatory hormone that is conserved in fish, amphibians, and mammalians. Here we report the genomic and…”
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Effect of glucocorticoid administration on serum aldosterone concentration in clinically normal dogs by Corrigan, Anne M, Behrend, Ellen N, Martin, Linda G, Kemppainen, Robert J

“…To evaluate the effects of oral administration of anti-inflammatory dosages of prednisone for 28 days on serum aldosterone, cortisol, and electrolyte…”
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