Search Results - "Kempny, Michał"

Sulfamide antifolates inhibiting thymidylate synthase: synthesis, enzyme inhibition and cytotoxicity by Pawełczak, Krzysztof, Makowski, Maciej, Kempny, Michał, Dzik, Jolanta M, Gołos, Barbara, Rode, Wojciech, Rzeszotarska, Barbara

“…Synthesis and biological evaluation are described of seven new analogues (3-9) of two potent thymidylate synthase inhibitors, 10-propargyl-5,8-dideazafolate…”
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Synthesis of N -(4-propargylaminobenzoyl)-L-glutamates by Kempny Michal, Rzeszotarska Barbara, Pawelczak Krzysztof

“…To facilitate the rather labour consuming synthesis of antifolate γ-oligo-L-glutamates including those with the propargyl group at position N10 , two synthons…”
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An Improved Synthesis of t-Butyl N-(4-propargylaminobenzoyl)-γ-oligo (L-glutamate )s by Kempny Michal, Rzeszotarska Barbara, Pawelczak Krzysztof

“…A simple synthesis in solution, of the series of six consecutive t-butyl N-(4-propargylaminobenzoyl)-yoligo( L-glutamate)s (8-13) containing from two to seven…”
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Thymidylate synthases from Hymenolepis diminuta and regenerating rat liver: purification, properties, and inhibition by substrate and cofactor analogues by Cieśla, Joanna, Gołos, Barbara, Dzik, Jolanta M., Pawełczak, Krzysztof, Kempny, Michał, Makowski, Maciej, Bretner, Maria, Kulikowski, Tadeusz, Machnicka, Barbara, Rzeszotarska, Barbara, Rode, Wojciech

“…Comparative studies of thymidylate synthases, isolated from the tapeworm, Hymenolepis diminuta, and regenerating liver of its host, rat, aimed at a possibility…”
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New adsorbents for thymidylate synthase affinity chromatography by PAWEŁCZAK, K, KRZYZANOWSKI, L, RZESZOTARSKA, B, KEMPNY, M, WIECZOREK, P, CIESLA, J, RODE, W

“…New affinity adsorbents, intended for chromatography of thymidylate synthase (EC 2.1.1.45) from different sources, consisting of p…”
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Quinazoline antifolates inhibiting thymidylate synthase: synthesis of four oligo(L-.gamma.-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid and their enzyme inhibition by Pawelczak, Krzysztof, Jones, Terence R, Kempny, Michal, Jackman, Ann L, Newell, David R, Krzyzanowski, Leszek, Rzeszotarska, Barbara

“…The synthesis is described of four oligo(gamma-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid containing a total of two, three, four, and five…”
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