Search Results - "Kemp, Melissa"

Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance by Lewis, Joshua E., Kemp, Melissa L.

“…Resistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitivity is…”
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A bird's-eye view of avian extinctions by Kemp, Melissa E

“…Conservation should consider species' functional and phylogenetic traits…”
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Assembly, Persistence, and Disassembly Dynamics of Quaternary Caribbean Frugivore Communities by Kemp, Melissa E

“…AbstractHow communities assemble and restructure is of critical importance to ecological theory, evolutionary theory, and conservation, but long-term…”
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Defaunation and species introductions alter long-term functional trait diversity in insular reptiles by Kemp, Melissa E

“…Biodiversity loss poses a major threat to ecosystem function, which has already been severely impacted by global late-Quaternary defaunation. The loss of…”
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Agent-based modeling of morphogenetic systems: Advantages and challenges by Glen, Chad M, Kemp, Melissa L, Voit, Eberhard O

“…The complexity of morphogenesis poses a fundamental challenge to understanding the mechanisms governing the formation of biological patterns and structures…”
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7000 years of turnover: historical contingency and human niche construction shape the Caribbean's Anthropocene biota by Kemp, Melissa E, Mychajliw, Alexis M, Wadman, Jenna, Goldberg, Amy

“…The human-mediated movement of species across biogeographic boundaries-whether intentional or accidental-is dramatically reshaping the modern world. Yet humans…”
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Identification of Late Pleistocene and Holocene fossil lizards from Hall's Cave (Kerr County, Texas) and a primer on morphological variation in North American lizard skulls by Ledesma, David T, Scarpetta, Simon G, Jacisin, 3rd, John J, Meza, Antonio, Kemp, Melissa E

“…Fossil identification practices have a profound effect on our interpretation of the past because these identifications form the basis for downstream analyses…”
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Early dynamic changes in iPSC oxygen consumption rate predict future cardiomyocyte differentiation by Nikitina, Arina A., Roysam, Tanya, Kemp, Melissa L.

“…Human induced pluripotent stem cells (iPSCs) hold great promise for reducing the mortality of cardiovascular disease by cellular replacement of infarcted…”
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Multiplex cytological profiling assay to measure diverse cellular states by Gustafsdottir, Sigrun M, Ljosa, Vebjorn, Sokolnicki, Katherine L, Anthony Wilson, J, Walpita, Deepika, Kemp, Melissa M, Petri Seiler, Kathleen, Carrel, Hyman A, Golub, Todd R, Schreiber, Stuart L, Clemons, Paul A, Carpenter, Anne E, Shamji, Alykhan F

“…Computational methods for image-based profiling are under active development, but their success hinges on assays that can capture a wide range of phenotypes…”
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Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment by Glen, Chad M., McDevitt, Todd C., Kemp, Melissa L.

“…The initiation of heterogeneity within a population of phenotypically identical progenitors is a critical event for the onset of morphogenesis and…”
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TiO2 Nanoparticle-Induced Oxidation of the Plasma Membrane: Importance of the Protein Corona by Runa, Sabiha, Lakadamyali, Melike, Kemp, Melissa L, Payne, Christine K

“…Titanium dioxide (TiO2) nanoparticles, used as pigments and photocatalysts, are widely present in modern society. Inhalation or ingestion of these…”
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A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses by Adimora, Nnenna J, Jones, Dean P, Kemp, Melissa L

“…Hydrogen peroxide is appreciated as a cellular signaling molecule with second-messenger properties, yet the mechanisms by which the cell protects against…”
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Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance by Badran, Ahmed H., Guzov, Victor M., Huai, Qing, Kemp, Melissa M., Vishwanath, Prashanth, Kain, Wendy, Nance, Autumn M., Evdokimov, Artem, Moshiri, Farhad, Turner, Keith H., Wang, Ping, Malvar, Thomas, Liu, David R.

“…The Bacillus thuringiensis δ-endotoxins (Bt toxins) are widely used insecticidal proteins in engineered crops that provide agricultural, economic, and…”
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Imaging Single-Cell Signaling Dynamics with a Deterministic High-Density Single-Cell Trap Array by Chung, Kwanghun, Rivet, Catherine A, Kemp, Melissa L, Lu, Hang

“…Stochasticity in gene expression, protein or metabolite levels contributes to cell–cell variations, the analysis of which could lead to a better understanding…”
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TiO2 Nanoparticles Alter the Expression of Peroxiredoxin Antioxidant Genes by Runa, Sabiha, Khanal, Dipesh, Kemp, Melissa L, Payne, Christine K

“…Titanium dioxide (TiO2) nanoparticles are used industrially and commercially at increasingly high levels. While toxicity is addressed prior to use, it is also…”
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iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays by Fay, Meredith E., Oshinowo, Oluwamayokun, Iffrig, Elizabeth, Fibben, Kirby S., Caruso, Christina, Hansen, Scott, Musick, Jamie O., Valdez, José M., Azer, Sally S., Mannino, Robert G., Choi, Hyoann, Zhang, Dan Y., Williams, Evelyn K., Evans, Erica N., Kanne, Celeste K., Kemp, Melissa L., Sheehan, Vivien A., Carden, Marcus A., Bennett, Carolyn M., Wood, David K., Lam, Wilbur A.

“…While microscopy-based cellular assays, including microfluidics, have significantly advanced over the last several decades, there has not been concurrent…”
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Morphometric analyses of the vertebrae of Ambystoma (Tschudi, 1838) and the implications for identification of fossil salamanders by Ledesma, David T., Ayala, Alissandra, Kemp, Melissa E.

“…Ambystoma (Tschudi, 1838) represents a speciose clade of salamanders that are found across much of North America. Fossils referred to Ambystoma are reported…”
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Mass Spectrometry Imaging Reveals Early Metabolic Priming of Cell Lineage in Differentiating Human-Induced Pluripotent Stem Cells by Nikitina, Arina A., Van Grouw, Alexandria, Roysam, Tanya, Huang, Danning, Fernández, Facundo M., Kemp, Melissa L.

“…Induced pluripotent stem cells (iPSCs) hold great promise in regenerative medicine; however, few algorithms of quality control at the earliest stages of…”
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Oscillatory IL-2 stimulus reveals pertinent signaling timescales of T cell responsiveness by Kippner, Linda E, Kemp, Melissa L

“…Cell response to extracellular ligand is affected not only by ligand availability, but also by pre-existing cell-to-cell variability that enables a range of…”
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Dynamic Mitochondrial Migratory Features Associated with Calcium Responses during T Cell Antigen Recognition by He, Luye, Raddatz, Andrew D, Zhou, Fangyuan, Hwang, Hyundoo, Kemp, Melissa L, Lu, Hang

“…A T cell clone is able to distinguish Ags in the form of peptide-MHC complexes with high specificity and sensitivity; however, how subtle differences in…”
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