Search Results - "Kemp, Benjamin P."
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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
Published in Nature communications (14-09-2015)“…In response to infections and irritants, the respiratory epithelium releases the alarmin interleukin (IL)-33 to elicit a rapid immune response. However, little…”
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Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
Published in Scientific reports (17-06-2023)“…Interleukin (IL)-33 is a broad-acting alarmin cytokine that can drive inflammatory responses following tissue damage or infection and is a promising target for…”
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S cysteine-rich (SCR) binding domain analysis of the Brassica self-incompatibility S-locus receptor kinase
Published in The New phytologist (01-01-2007)“…Brassica self-incompatibility, a highly discriminating outbreeding mechanism, has become a paradigm for the study of plant cell-cell communications. When…”
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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses
Published in Annals of the rheumatic diseases (01-02-2019)“…Immune complexes (ICs) play a critical role in the pathology of autoimmune diseases. The aim of this study was to generate and characterise a first-in-class…”
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Xanthomonas axonopodis pv. manihotis gumD gene is essential for EPS production and pathogenicity and enhances epiphytic survival on cassava ( Manihot esculenta)
Published in Physiological and molecular plant pathology (01-04-2004)“…Extracellular polysaccharide-defective (EPS −) mutants of the cassava blight pathogen, Xanthomonas axonopodis pv. manihotis, were created by targeted…”
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Just how complex is the Brassica S‐receptor complex?
Published in Journal of experimental botany (01-01-2003)“…Of the plant self‐incompatibility (SI) systems investigated to date, that possessed by members of the Brassicaceae is currently the best understood. Whilst the…”
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