Search Results - "Kemp, A. J."

Numerical methods for particle simulations at extreme densities and temperatures: Weighted particles, relativistic collisions and reduced currents by Sentoku, Y., Kemp, A.J.

“…We present a fully relativistic energy-conserving binary collision model for particle simulations with large density scale plasmas. Our model deals with…”
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Spatiotemporal dynamics of fast electron heating in solid-density matter via XFEL by Sawada, H., Yabuuchi, T., Higashi, N., Iwasaki, T., Kawasaki, K., Maeda, Y., Izumi, T., Nakagawa, Y., Shigemori, K., Sakawa, Y., Curry, C. B., Frost, M., Iwata, N., Ogitsu, T., Sueda, K., Togashi, T., Hu, S. X., Glenzer, S. H., Kemp, A. J., Ping, Y., Sentoku, Y.

“…High-intensity, short-pulse lasers are crucial for generating energetic electrons that produce high-energy-density (HED) states in matter, offering potential…”
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Generating keV ion distributions for nuclear reactions at near solid-density using intense short-pulse lasers by Kemp, A. J., Wilks, S. C., Hartouni, E. P., Grim, G.

“…Our understanding of a large range of astrophysical phenomena depends on a precise knowledge of charged particle nuclear reactions that occur at very low…”
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Emergence of early alterations in network oscillations and functional connectivity in a tau seeding mouse model of Alzheimer’s disease pathology by Ahnaou, A., Moechars, D., Raeymaekers, L., Biermans, R., Manyakov, N. V., Bottelbergs, A., Wintmolders, C., Van Kolen, K., Van De Casteele, T., Kemp, J. A., Drinkenburg, W. H.

“…Synaptic dysfunction and disconnectivity are core deficits in Alzheimer’s disease (AD), preceding clear changes in histopathology and cognitive functioning…”
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Comment on "In-depth Plasma-Wave Heating of Dense Plasma Irradiated by Short Laser Pulses" by Kemp, A J, Sentoku, Y

“…Sherlock et al. have reported on the heating of solid density targets by collisional damping of wakefields that are driven by relativistic electron bunches…”
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Hot-electron energy coupling in ultraintense laser-matter interaction by Kemp, A J, Sentoku, Y, Tabak, M

“…We investigate the hydrodynamic response of plasma gradients during the interaction with ultraintense energetic laser pulses, using kinetic particle…”
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Deflection of MeV electrons by self-generated magnetic fields in intense laser-solid interactions by Pérez, F, Kemp, A J, Divol, L, Chen, C D, Patel, P K

“…We show that the interaction of relativistic-intensity, picosecond laser pulses with solid targets is affected by the reflected light through the strong…”
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Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis by Pepys, M. B, Herbert, J, Hutchinson, W. L, Tennent, G. A, Lachmann, H. J, Gallimore, J. R, Lovat, L. B, Bartfai, T, Alanine, A, Hertel, C, Hoffmann, T, Jakob-Roetne, R, Norcross, R. D, Kemp, J. A, Yamamura, K, Suzuki, M, Taylor, G. W, Murray, S, Thompson, D, Purvis, A, Kolstoe, S, Wood, S. P, Hawkins, P. N

“…The normal plasma protein serum amyloid P component (SAP) binds to fibrils in all types of amyloid deposits, and contributes to the pathogenesis of…”
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Collisional relaxation of superthermal electrons generated by relativistic laser pulses in dense plasma by Kemp, A J, Sentoku, Y, Sotnikov, V, Wilks, S C

“…Energy relaxation of the hot electron population generated by relativistic laser pulses in overdense plasma is analyzed for densities ranging from below to…”
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Simulation of laser–plasma interactions and fast-electron transport in inhomogeneous plasma by Cohen, B.I., Kemp, A.J., Divol, L.

“…A new framework is introduced for kinetic simulation of laser–plasma interactions in an inhomogeneous plasma motivated by the goal of performing integrated…”
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Dynamics of relativistic laser-plasma interaction on solid targets by Ping, Y, Kemp, A J, Divol, L, Key, M H, Patel, P K, Akli, K U, Beg, F N, Chawla, S, Chen, C D, Freeman, R R, Hey, D, Higginson, D P, Jarrott, L C, Kemp, G E, Link, A, McLean, H S, Sawada, H, Stephens, R B, Turnbull, D, Westover, B, Wilks, S C

“…A novel time-resolved diagnostic is used to record the critical surface motion during picosecond-scale relativistic laser interaction with a solid target…”
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Laser heating of solid matter by light-pressure-driven shocks at ultrarelativistic intensities by Akli, K U, Hansen, S B, Kemp, A J, Freeman, R R, Beg, F N, Clark, D C, Chen, S D, Hey, D, Hatchett, S P, Highbarger, K, Giraldez, E, Green, J S, Gregori, G, Lancaster, K L, Ma, T, MacKinnon, A J, Norreys, P, Patel, N, Pasley, J, Shearer, C, Stephens, R B, Stoeckl, C, Storm, M, Theobald, W, Van Woerkom, L D, Weber, R, Key, M H

“…The heating of solid targets irradiated by 5 x 10(20) W cm(-2), 0.8 ps, 1.05 microm wavelength laser light is studied by x-ray spectroscopy of the K-shell…”
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Hot electron temperature and coupling efficiency scaling with prepulse for cone-guided fast ignition by Ma, T, Sawada, H, Patel, P K, Chen, C D, Divol, L, Higginson, D P, Kemp, A J, Key, M H, Larson, D J, Le Pape, S, Link, A, MacPhee, A G, McLean, H S, Ping, Y, Stephens, R B, Wilks, S C, Beg, F N

“…The effect of increasing prepulse energy levels on the energy spectrum and coupling into forward-going electrons is evaluated in a cone-guided fast-ignition…”
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Interaction physics of multipicosecond Petawatt laser pulses with overdense plasma by Kemp, A J, Divol, L

“…We study the interaction of intense petawatt laser pulses with overdense plasma over several picoseconds, using two- and three-dimensional kinetic particle…”
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Translational neurophysiological markers for activity of the metabotropic glutamate receptor (mGluR2) modulator JNJ-40411813: Sleep EEG correlates in rodents and healthy men by Ahnaou, A., de Boer, P., Lavreysen, H., Huysmans, H., Sinha, V., Raeymaekers, L., Van De Casteele, T., Cid, J.M., Van Nueten, L., Macdonald, G.J., Kemp, J.A., Drinkenburg, W.H.I.M.

“…Alterations in rapid eye movement sleep (REM) have been suggested as valid translational efficacy markers: activation of the metabotropic glutamate receptor 2…”
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Evaluation of the NR2B-selective NMDA receptor antagonist Ro 63-1908 on rodent behaviour: evidence for an involvement of NR2B NMDA receptors in response inhibition by Higgins, G.A., Ballard, T.M., Huwyler, J., Kemp, J.A., Gill, R.

“…We have characterised the effects of the recently described NMDA NR2B subtype selective antagonist, Ro 63-1908, on spontaneous behaviour and in tasks sensitive…”
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The glycine site of the NMDA receptor--five years on by Kemp, J A, Leeson, P D

“…The glycine site on the NMDA receptor complex has generated an enormous amount of interest since it was first described five years ago. In this review by John…”
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Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro by Fischer, G, Mutel, V, Trube, G, Malherbe, P, Kew, J N, Mohacsi, E, Heitz, M P, Kemp, J A

“…The interaction of Ro 25-6981 with N-methyl-D-aspartate (NMDA) receptors was characterized by a variety of different tests in vitro. Ro 25-6981 inhibited…”
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Effect of bone meal (calcium phosphate) amendments on metal release from contaminated soils — a leaching column study by Hodson, M.E, Valsami-Jones, E, Cotter-Howells, J.D, Dubbin, W.E, Kemp, A.J, Thornton, I, Warren, A

“…Bone meal reduced metal release from a contaminated soil. Metal-contaminated soil may be remediated in situ by the formation of highly insoluble metal…”
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A guide for surveillance of patients with Barrett's esophagus by Provenzale, D, Kemp, J A, Arora, S, Wong, J B

“…Barrett's esophagus (columnar metaplasia of the distal esophagus due to chronic gastroesophageal reflux) affects nearly 700,000 people in the United States,…”
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