Search Results - "Kemmis, Carly M"

Human mammary epithelial cells express CYP27B1 and are growth inhibited by 25-hydroxyvitamin D-3, the major circulating form of vitamin D-3 by Kemmis, Carly M, Salvador, Sally M, Smith, Kelly M, Welsh, JoEllen

“…1alpha,25-dihydroxycholecalciferol [1alpha,25(OH)2D3], the active form of cholecalciferol, is a negative growth regulator of breast cancer cells. CYP27B1 is a…”
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Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells by Rowling, Matthew J, Kemmis, Carly M, Taffany, David A, Welsh, JoEllen

“…The major circulating form of vitamin D is 25-hydroxycholecalciferol [25(OH)D3], which is delivered to target tissues in complex with the serum vitamin D…”
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Mammary epithelial cell transformation is associated with deregulation of the vitamin D pathway by Kemmis, Carly M., Welsh, JoEllen

“…The vitamin D endocrine system mediates anti‐proliferative and pro‐differentiating signaling in multiple epithelial tissues, including mammary gland and breast…”
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Bone morphogenetic protein 6 drives both osteogenesis and chondrogenesis in murine adipose-derived mesenchymal cells depending on culture conditions by Kemmis, Carly M., Vahdati, Ali, Weiss, Holly E., Wagner, Diane R.

“…► BMP-6 promotes osteogenesis in murine ASCs in monolayer. ► BMP-6 also induces chondrogenesis in murine ASCs cultured in pellets. ► Both osteo- and…”
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Investigation of 1,25D synthesis and vitamin D3 signaling in human mammary epithelial cells by Kemmis, Carly M

“…The classic function of vitamin D is maintenance of calcium homeostasis through tight regulation of circulating 1,25D via synthesis and degradation in the…”
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