Search Results - "Kemény, Lajos V"

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl - Channel by Venglovecz, Viktória, Pallagi, Petra, Kemény, Lajos V, Balázs, Anita, Balla, Zsolt, Becskeházi, Eszter, Gál, Eleonóra, Tóth, Emese, Zvara, Ágnes, Puskás, László G, Borka, Katalin, Sendler, Matthias, Lerch, Markus M, Mayerle, Julia, Kühn, Jens-Peter, Rakonczay, Jr, Zoltán, Hegyi, Péter

“…Aquaporins (AQPs) facilitate the transepithelial water flow involved in epithelial fluid secretion in numerous tissues; however, their function in the pancreas…”
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Melanoma-Derived BRAFV600E Mutation in Peritumoral Stromal Cells: Implications for in Vivo Cell Fusion by Kurgyis, Zsuzsanna, Kemény, Lajos, Buknicz, Tünde, Groma, Gergely, Oláh, Judit, Jakab, Ádám, Polyánka, Hilda, Zänker, Kurt, Dittmar, Thomas, Németh, István

“…Melanoma often recurs in patients after the removal of the primary tumor, suggesting the presence of recurrent tumor-initiating cells that are undetectable…”
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The Skin-Brain Axis: From UV and Pigmentation to Behaviour Modulation by Ascsillán, Anna A, Kemény, Lajos V

“…The skin-brain axis has been suggested to play a role in several pathophysiological conditions, including opioid addiction, Parkinson's disease and many…”
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NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism by Allouche, Jennifer, Rachmin, Inbal, Adhikari, Kaustubh, Pardo, Luba M., Lee, Ju Hee, McConnell, Alicia M., Kato, Shinichiro, Fan, Shaohua, Kawakami, Akinori, Suita, Yusuke, Wakamatsu, Kazumasa, Igras, Vivien, Zhang, Jianming, Navarro, Paula P., Lugo, Camila Makhlouta, Noonan, Haley R., Christie, Kathleen A., Itin, Kaspar, Mujahid, Nisma, Lo, Jennifer A., Won, Chong Hyun, Evans, Conor L., Weng, Qing Yu, Wang, Hequn, Osseiran, Sam, Lovas, Alyssa, Németh, István, Cozzio, Antonio, Navarini, Alexander A., Hsiao, Jennifer J., Nguyen, Nhu, Kemény, Lajos V., Iliopoulos, Othon, Berking, Carola, Ruzicka, Thomas, Gonzalez-José, Rolando, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Acuna-Alonso, Victor, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Ito, Shosuke, Schiaffino, Maria Vittoria, Chao, Luke H., Kleinstiver, Benjamin P., Tishkoff, Sarah, Zon, Leonard I., Nijsten, Tamar, Ruiz-Linares, Andrés, Fisher, David E., Roider, Elisabeth

“…Ultraviolet (UV) light and incompletely understood genetic and epigenetic variations determine skin color. Here we describe an UV- and…”
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Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion by Tateishi, Kensuke, Wakimoto, Hiroaki, Iafrate, A. John, Tanaka, Shota, Loebel, Franziska, Lelic, Nina, Wiederschain, Dmitri, Bedel, Olivier, Deng, Gejing, Zhang, Bailin, He, Timothy, Shi, Xu, Gerszten, Robert E., Zhang, Yiyun, Yeh, Jing-Ruey J., Curry, William T., Zhao, Dan, Sundaram, Sudhandra, Nigim, Fares, Koerner, Mara V.A., Ho, Quan, Fisher, David E., Roider, Elisabeth M., Kemeny, Lajos V., Samuels, Yardena, Flaherty, Keith T., Batchelor, Tracy T., Chi, Andrew S., Cahill, Daniel P.

“…Heterozygous mutation of IDH1 in cancers modifies IDH1 enzymatic activity, reprogramming metabolite flux and markedly elevating 2-hydroxyglutarate (2-HG)…”
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Hepatocyte vitamin D receptor functions as a nutrient sensor that regulates energy storage and tissue growth in zebrafish by Freeburg, Scott H., Shwartz, Arkadi, Kemény, Lajos V., Smith, Colton J., Weeks, Olivia, Miller, Bess M., PenkoffLidbeck, Nadia, Fisher, David E., Evason, Kimberley J., Goessling, Wolfram

“…Vitamin D receptor (VDR) has been implicated in fatty liver pathogenesis, but its role in the regulation of organismal energy usage remains unclear. Here, we…”
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Alcohol Disrupts Levels and Function of the Cystic Fibrosis Transmembrane Conductance Regulator to Promote Development of Pancreatitis by Maléth, József, Balázs, Anita, Pallagi, Petra, Balla, Zsolt, Kui, Balázs, Katona, Máté, Judák, Linda, Németh, István, Kemény, Lajos V., Rakonczay, Zoltán, Venglovecz, Viktória, Földesi, Imre, Pető, Zoltán, Somorácz, Áron, Borka, Katalin, Perdomo, Doranda, Lukacs, Gergely L., Gray, Mike A., Monterisi, Stefania, Zaccolo, Manuela, Sendler, Matthias, Mayerle, Julia, Kühn, Jens-Peter, Lerch, Markus M., Sahin-Tóth, Miklós, Hegyi, Péter

“…Excessive consumption of ethanol is one of the most common causes of acute and chronic pancreatitis. Alterations to the gene encoding the cystic fibrosis…”
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Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis by Kato, Shinichiro, Weng, Qing Yu, Insco, Megan L, Chen, Kevin Y, Muralidhar, Sathya, Pozniak, Joanna, Diaz, Joey Mark S, Drier, Yotam, Nguyen, Nhu, Lo, Jennifer A, van Rooijen, Ellen, Kemeny, Lajos V, Zhan, Yao, Feng, Yang, Silkworth, Whitney, Powell, C Thomas, Liau, Brian B, Xiong, Yan, Jin, Jian, Newton-Bishop, Julia, Zon, Leonard I, Bernstein, Bradley E, Fisher, David E

“…Epigenetic regulators, when genomically altered, may become driver oncogenes that mediate otherwise unexplained pro-oncogenic changes lacking a clear genetic…”
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Melanoma Cells Can Adopt the Phenotype of Stromal Fibroblasts and Macrophages by Spontaneous Cell Fusion in Vitro by Kemény, Lajos V, Kurgyis, Zsuzsanna, Buknicz, Tünde, Groma, Gergely, Jakab, Ádám, Zänker, Kurt, Dittmar, Thomas, Kemény, Lajos, Németh, István B

“…After the removal of primary cutaneous melanoma some patients develop local recurrences, even after having histologically tumor-free re-excision. A potential…”
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Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions by Skinner, Owen S., Blanco-Fernández, Joan, Goodman, Russell P., Kawakami, Akinori, Shen, Hongying, Kemény, Lajos V., Joesch-Cohen, Lena, Rees, Matthew G., Roth, Jennifer A., Fisher, David E., Mootha, Vamsi K., Jourdain, Alexis A.

“…Glucose is vital for life, serving as both a source of energy and carbon building block for growth. When glucose is limiting, alternative nutrients must be…”
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A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin by Mujahid, Nisma, Liang, Yanke, Murakami, Ryo, Choi, Hwan Geun, Dobry, Allison S., Wang, Jinhua, Suita, Yusuke, Weng, Qing Yu, Allouche, Jennifer, Kemeny, Lajos V., Hermann, Andrea L., Roider, Elisabeth M., Gray, Nathanael S., Fisher, David E.

“…The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin…”
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MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species by Roider, Elisabeth, Lakatos, Alexandra I. T., McConnell, Alicia M., Wang, Poguang, Mueller, Alina, Kawakami, Akinori, Tsoi, Jennifer, Szabolcs, Botond L., Ascsillán, Anna A., Suita, Yusuke, Igras, Vivien, Lo, Jennifer A., Hsiao, Jennifer J., Lapides, Rebecca, Pál, Dorottya M. P., Lengyel, Anna S., Navarini, Alexander, Okazaki, Arimichi, Iliopoulos, Othon, Németh, István, Graeber, Thomas G., Zon, Leonard, Giese, Roger W., Kemeny, Lajos V., Fisher, David E.

“…Microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte function, development and plays a significant role in melanoma…”
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An Observational Study on the Molecular Profiling of Primary Melanomas Reveals a Progression Dependence on Mitochondrial Activation by Gil, Jeovanis, Rezeli, Melinda, Lutz, Elmar G., Kim, Yonghyo, Sugihara, Yutaka, Malm, Johan, Semenov, Yevgeniy R., Yu, Kun-Hsing, Nguyen, Nga, Wan, Guihong, Kemény, Lajos V., Kárpáti, Sarolta, Németh, István Balázs, Marko-Varga, György

“…Melanoma in advanced stages is one of the most aggressive tumors and the deadliest of skin cancers. To date, the histopathological staging focuses on tumor…”
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β-Endorphin mediates radiation therapy fatigue by Hermann, Andrea L, Fell, Gillian L, Kemény, Lajos V, Fung, Claire Y, Held, Kathryn D, Biggs, Peter J, Rivera, Phillip D, Bilbo, Staci D, Igras, Vivien, Willers, Henning, Kung, Jong, Gheorghiu, Liliana, Hideghéty, Katalin, Mao, Jianren, Woolf, Clifford J, Fisher, David E

“…Fatigue is a common adverse effect of external beam radiation therapy in cancer patients. Mechanisms causing radiation fatigue remain unclear, although linkage…”
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Reduced MC4R signaling alters nociceptive thresholds associated with red hair by Robinson, Kathleen C, Kemény, Lajos V, Fell, Gillian L, Hermann, Andrea L, Allouche, Jennifer, Ding, Weihua, Yekkirala, Ajay, Hsiao, Jennifer J, Su, Mack Y, Theodosakis, Nicholas, Kozak, Gabor, Takeuchi, Yuichi, Shen, Shiqian, Berenyi, Antal, Mao, Jianren, Woolf, Clifford J, Fisher, David E

“…Humans and mice with natural red hair have elevated basal pain thresholds and an increased sensitivity to opioid analgesics. We investigated the mechanisms…”
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Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation by Kurgyis, Zsuzsanna, Vornholz, Larsen, Pechloff, Konstanze, Kemény, Lajos V, Wartewig, Tim, Muschaweckh, Andreas, Joshi, Abhinav, Kranen, Katja, Hartjes, Lara, Möckel, Sigrid, Steiger, Katja, Hameister, Erik, Volz, Thomas, Mellett, Mark, French, Lars E, Biedermann, Tilo, Korn, Thomas, Ruland, Jürgen

“…Psoriasis is a chronic inflammatory skin disease arising from poorly defined pathological cross-talk between keratinocytes and the immune system. BCL10 (B cell…”
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Expression of aquaporins in pancreatic ductal cells by Venglovecz, Viktoria, Kemény, Lajos V, Rakonczay, Zoltán, Zvara, Ágnes, Puskás, László, Hegyi, Péter

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Vitamin D deficiency exacerbates UV/endorphin and opioid addiction by Kemény, Lajos V, Robinson, Kathleen C, Hermann, Andrea L, Walker, Deena M, Regan, Susan, Yew, Yik Weng, Lai, Yi Chun, Theodosakis, Nicholas, Rivera, Phillip D, Ding, Weihua, Yang, Liuyue, Beyer, Tobias, Loh, Yong-Hwee E, Lo, Jennifer A, van der Sande, Anita A J, Sarnie, William, Kotler, David, Hsiao, Jennifer J, Su, Mack Y, Kato, Shinichiro, Kotler, Joseph, Bilbo, Staci D, Chopra, Vanita, Salomon, Matthew P, Shen, Shiqian, Hoon, Dave S B, Asgari, Maryam M, Wakeman, Sarah E, Nestler, Eric J, Fisher, David E

“…The current opioid epidemic warrants a better understanding of genetic and environmental factors that contribute to opioid addiction. Here we report an…”
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CFTR loss of function after alcohol consumption and in alcoholic pancreatitis by Maléth, József, Pallagi, Petra, Kemény, Lajos V, Balla, Zsolt, Kui, Balázs, Balázs, Anita, Judák, Linda, Németh, István, Rakonczay, Zoltán, Venglovecz, Viktória, Földesi, Imre, Somorácz, Áron, Borka, Katalain, Perdomo, Doranda, Lukacs, Gergely L, Gray, Mike A, Monterisi, Stefania, Zaccolo, Manuela, Lerch, Markus, Sahin-Tóth, Miklós, Hegyi, Péter

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Retrospective analysis of patients with chronic pancreatitis in Hungary based on the data from the Hungarian National Pancreas Registry by Dubravcsik, Zsolt, Balázs, Anita, Kemény, Lajos V, Hritz, István, Gervain, Judit, Izbéki, Ferenc, Szepes, Attila, Gyimesi, György, Kelemen, Dezsö, Csiszkó, Adrienn, Szentkereszty, Zsolt, Bod, Barnabás, Vincze, Áron, Bajor, Judit, Szmola, Richárd, Párniczky, Andrea, Lásztity, Natália, Sümegi, János, Andorka, Csilla, Veres, Gábor, Czelecz, Judit, Novák, János, Farkas, Gyula, Czakó, László, Takács, Tamás, Rakonczay, Zoltán, Maléth, József János, Pap, Ákos, Hegyi, Péter

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