Search Results - "Kelly Cho"

Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans by Dickerman, Barbra A, Gerlovin, Hanna, Madenci, Arin L, Kurgansky, Katherine E, Ferolito, Brian R, Figueroa Muñiz, Michael J, Gagnon, David R, Gaziano, J. Michael, Cho, Kelly, Casas, Juan P, Hernán, Miguel A

“…In an observational study involving nearly 440,000 veterans, both the BNT162b2 vaccine and the mRNA-1273 vaccine were highly effective at preventing infection,…”
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Diabetes Mellitus-Related All-Cause and Cardiovascular Mortality in a National Cohort of Adults by Raghavan, Sridharan, Vassy, Jason L, Ho, Yuk-Lam, Song, Rebecca J, Gagnon, David R, Cho, Kelly, Wilson, Peter W F, Phillips, Lawrence S

“…Background Diabetes mellitus is a risk factor for cardiovascular disease ( CVD ) and has been associated with 2- to 4-fold higher mortality. Diabetes…”
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Prescription opioid duration of action and the risk of unintentional overdose among patients receiving opioid therapy by Miller, Matthew, Barber, Catherine W, Leatherman, Sarah, Fonda, Jennifer, Hermos, John A, Cho, Kelly, Gagnon, David R

“…The unprecedented increase in unintentional overdose events that has occurred in tandem with escalating sales of prescription opioids over the past 2 decades…”
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Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies by Fang, Huaying, Hui, Qin, Lynch, Julie, Honerlaw, Jacqueline, Assimes, Themistocles L., Huang, Jie, Vujkovic, Marijana, Damrauer, Scott M., Pyarajan, Saiju, Gaziano, J. Michael, DuVall, Scott L., O’Donnell, Christopher J., Cho, Kelly, Chang, Kyong-Mi, Wilson, Peter W.F., Tsao, Philip S., Gaziano, J. Michael, Ramoni, Rachel, Breeling, Jim, Chang, Kyong-Mi, Huang, Grant, Muralidhar, Sumitra, O’Donnell, Christopher J., Tsao, Philip S., Moser, Jennifer, Whitbourne, Stacey B., Brewer, Jessica V., Warren, Stuart, Argyres, Dean P., Stephens, Brady, Brophy, Mary T., Humphries, Donald E., Do, Nhan, Shayan, Shahpoor, Nguyen, Xuan-Mai T., Pyarajan, Saiju, Cho, Kelly, Hauser, Elizabeth, Sun, Yan, Zhao, Hongyu, Wilson, Peter, McArdle, Rachel, Dellitalia, Louis, Harley, John, Whittle, Jeffrey, Beckham, Jean, Wells, John, Gutierrez, Salvador, Gibson, Gretchen, Kaminsky, Laurence, Villareal, Gerardo, Kinlay, Scott, Xu, Junzhe, Hamner, Mark, Haddock, Kathlyn Sue, Bhushan, Sujata, Iruvanti, Pran, Godschalk, Michael, Ballas, Zuhair, Buford, Malcolm, Mastorides, Stephen, Klein, Jon, Ratcliffe, Nora, Florez, Hermes, Swann, Alan, Murdoch, Maureen, Sriram, Peruvemba, Yeh, Shing Shing, Washburn, Ronald, Jhala, Darshana, Aguayo, Samuel, Cohen, David, Sharma, Satish, Callaghan, John, Oursler, Kris Ann, Whooley, Mary, Ahuja, Sunil, Gutierrez, Amparo, Schifman, Ronald, Greco, Jennifer, Rauchman, Michael, Servatius, Richard, Oehlert, Mary, Wallbom, Agnes, Fernando, Ronald, Stapley, Todd, Sherman, Scott, Anderson, Gwenevere, Sonel, Elif, Boyko, Edward, Meyer, Laurence, Gupta, Samir, Fayad, Joseph, Hung, Adriana, Lichy, Jack, Hurley, Robin, Robey, Brooks, Striker, Robert, Sun, Yan V., Tang, Hua

“…Large-scale multi-ethnic cohorts offer unprecedented opportunities to elucidate the genetic factors influencing complex traits related to health and disease…”
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Genome-wide association study of peripheral artery disease in the Million Veteran Program by Klarin, Derek, Lynch, Julie, Aragam, Krishna, Chaffin, Mark, Assimes, Themistocles L., Huang, Jie, Lee, Kyung Min, Shao, Qing, Huffman, Jennifer E., Natarajan, Pradeep, Arya, Shipra, Small, Aeron, Sun, Yan V., Vujkovic, Marijana, Freiberg, Matthew S., Wang, Lu, Chen, Jinbo, Saleheen, Danish, Lee, Jennifer S., Miller, Donald R., Reaven, Peter, Alba, Patrick R., Patterson, Olga V., DuVall, Scott L., Boden, William E., Beckman, Joshua A., Gaziano, J. Michael, Concato, John, Rader, Daniel J., Cho, Kelly, Chang, Kyong-Mi, Wilson, Peter W. F., O’Donnell, Christopher J., Kathiresan, Sekar, Tsao, Philip S., Damrauer, Scott M.

“…Peripheral artery disease (PAD) is a leading cause of cardiovascular morbidity and mortality; however, the extent to which genetic factors increase risk for…”
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Million Veteran Program's response to COVID-19: Survey development and preliminary findings by Whitbourne, Stacey B, Nguyen, Xuan-Mai T, Song, Rebecca J, Lord, Emily, Lyden, Michelle, Harrington, Kelly M, Ward, Rachel, Li, Yanping, Brewer, Jessica V V, Cho, Kelly M, Djousse, Luc, Muralidhar, Sumitra, Tsao, Philip S, Gaziano, J Michael, Casas, Juan P

“…In response to the novel Coronavirus Disease 2019 (COVID-19) pandemic, the Department of Veterans Affairs (VA) Million Veteran Program (MVP) organized efforts…”
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Association of cancer and Alzheimer's disease risk in a national cohort of veterans by Frain, Laura, Swanson, David, Cho, Kelly, Gagnon, David, Lu, Kun Ping, Betensky, Rebecca A., Driver, Jane

“…To examine the risk of Alzheimer's disease (AD) among cancer survivors in a national database. Retrospective cohort of 3,499,378 mostly male US veterans aged…”
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Development and validation of a 30-day mortality index based on pre-existing medical administrative data from 13,323 COVID-19 patients: The Veterans Health Administration COVID-19 (VACO) Index by King, Jr, Joseph T, Yoon, James S, Rentsch, Christopher T, Tate, Janet P, Park, Lesley S, Kidwai-Khan, Farah, Skanderson, Melissa, Hauser, Ronald G, Jacobson, Daniel A, Erdos, Joseph, Cho, Kelly, Ramoni, Rachel, Gagnon, David R, Justice, Amy C

“…Available COVID-19 mortality indices are limited to acute inpatient data. Using nationwide medical administrative data available prior to SARS-CoV-2 infection…”
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Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans by Gelernter, Joel, Sun, Ning, Polimanti, Renato, Pietrzak, Robert, Levey, Daniel F., Bryois, Julien, Lu, Qiongshi, Hu, Yiming, Li, Boyang, Radhakrishnan, Krishnan, Aslan, Mihaela, Cheung, Kei-Hoi, Li, Yuli, Rajeevan, Nallakkandi, Sayward, Frederick, Harrington, Kelly, Chen, Quan, Cho, Kelly, Pyarajan, Saiju, Sullivan, Patrick F., Quaden, Rachel, Shi, Yunling, Hunter-Zinck, Haley, Gaziano, J. Michael, Concato, John, Zhao, Hongyu, Stein, Murray B.

“…Post-traumatic stress disorder (PTSD) is a major problem among military veterans and civilians alike, yet its pathophysiology remains poorly understood. We…”
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Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program by Small, Aeron M., Peloso, Gina M., Linefsky, Jason, Aragam, Jayashri, Galloway, Ashley, Tanukonda, Vidisha, Wang, Lu-Chen, Yu, Zhi, Sunitha Selvaraj, Margaret, Farber-Eger, Eric H., Baker, Michael T., Setia-Verma, Shefali, Lee, Simon S.K., Preuss, Michael, Ritchie, Marylyn D., Damrauer, Scott M., Rader, Daniel J., Wells, Quinn S., Loos, Ruth, Lubitz, Steven A., Thanassoulis, George, Cho, Kelly, Wilson, Peter W.F., Natarajan, Pradeep, O’Donnell, Christopher J.

“…Calcific aortic stenosis (CAS) is the most common valvular heart disease in older adults and has no effective preventive therapies. Genome-wide association…”
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Degree of adherence to plant-based diet and total and cause-specific mortality: prospective cohort study in the Million Veteran Program by Wang, Dong D, Li, Yanping, Nguyen, Xuan-Mai T, Song, Rebecca J, Ho, Yuk-Lam, Hu, Frank B, Willett, Walter C, Wilson, Peter, Cho, Kelly, Gaziano, J Michael, Djoussé, Luc

“…To examine the association between adherence to plant-based diets and mortality. Prospective study. We calculated a plant-based diet index (PDI) by assigning…”
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Genetic architecture of heart failure with preserved versus reduced ejection fraction by Joseph, Jacob, Liu, Chang, Hui, Qin, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E., Keaton, Jacob M., Edwards, Todd L., Demissie, Serkalem, Djousse, Luc, Casas, Juan P., Gaziano, J. Michael, Cho, Kelly, Wilson, Peter W. F., Phillips, Lawrence S., O’Donnell, Christopher J., Sun, Yan V.

“…Pharmacologic clinical trials for heart failure with preserved ejection fraction have been largely unsuccessful as compared to those for heart failure with…”
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Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure by Rasooly, Danielle, Peloso, Gina M., Pereira, Alexandre C., Dashti, Hesam, Giambartolomei, Claudia, Wheeler, Eleanor, Aung, Nay, Ferolito, Brian R., Pietzner, Maik, Farber-Eger, Eric H., Wells, Quinn Stanton, Kosik, Nicole M., Gaziano, Liam, Posner, Daniel C., Bento, A. Patrícia, Hui, Qin, Liu, Chang, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E., Wilson, Peter W. F., Phillips, Lawrence S., Whittaker, John, Munroe, Patricia B., Petersen, Steffen E., Cho, Kelly, Leach, Andrew R., Magariños, María Paula, Gaziano, John Michael, Langenberg, Claudia, Sun, Yan V., Joseph, Jacob, Casas, Juan P.

“…We conduct a large-scale meta-analysis of heart failure genome-wide association studies (GWAS) consisting of over 90,000 heart failure cases and more than 1…”
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Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization by Wang, Biqi, Dron, Jacqueline S., Wang, Yuxuan, Choi, Seung Hoan, Huffman, Jennifer E., Cho, Kelly, Wilson, Peter W. F., Natarajan, Pradeep, Peloso, Gina M.

“…Previous studies found lipid levels, especially triglycerides (TG), are associated with acute pancreatitis, but their causalities and bi-directions were not…”
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Random plasma glucose predicts the diagnosis of diabetes by Rhee, Mary K, Ho, Yuk-Lam, Raghavan, Sridharan, Vassy, Jason L, Cho, Kelly, Gagnon, David, Staimez, Lisa R, Ford, Christopher N, Wilson, Peter W F, Phillips, Lawrence S

“…Early recognition of those at high risk for diabetes as well as diabetes itself can permit preventive management, but many Americans with diabetes are…”
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Moderate alcohol consumption on the risk of stroke in the Million Veteran Program by Song, Rebecca J, Larson, Martin G, Aparicio, Hugo J, Gaziano, J Michael, Wilson, Peter, Cho, Kelly, Vasan, Ramachandran S, Fox, Matthew P, Djoussé, Luc

“…There is inconsistent evidence on the association of moderate alcohol consumption and stroke risk in the general population and is not well studied among U.S…”
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Visualizing novel connections and genetic similarities across diseases using a network-medicine based approach by Ferolito, Brian, do Valle, Italo Faria, Gerlovin, Hanna, Costa, Lauren, Casas, Juan P., Gaziano, J. Michael, Gagnon, David R., Begoli, Edmon, Barabási, Albert-László, Cho, Kelly

“…Understanding the genetic relationships between human disorders could lead to better treatment and prevention strategies, especially for individuals with…”
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Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records by Venkatesh, Samvida S., Ganjgahi, Habib, Palmer, Duncan S., Coley, Kayesha, Linchangco, Gregorio V., Hui, Qin, Wilson, Peter, Ho, Yuk-Lam, Cho, Kelly, Arumäe, Kadri, Wittemans, Laura B. L., Nellåker, Christoffer, Vainik, Uku, Sun, Yan V., Holmes, Chris, Lindgren, Cecilia M., Nicholson, George

“…Obesity is a heritable disease, characterised by excess adiposity that is measured by body mass index (BMI). While over 1,000 genetic loci are associated with…”
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Trajectories of Frailty in the 5 Years Prior to Death Among U.S. Veterans Born 1927–1934 by Ward, Rachel E, Orkaby, Ariela R, Dumontier, Clark, Charest, Brian, Hawley, Chelsea E, Yaksic, Enzo, Quach, Lien, Kim, Dae H, Gagnon, David R, Gaziano, J Michael, Cho, Kelly, Djousse, Luc, Driver, Jane A

“…Abstract Background Electronic frailty indices (eFIs) are increasingly used to identify patients at risk for morbidity and mortality. Whether eFIs capture the…”
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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program by Raghavan, Sridharan, Huang, Jie, Tcheandjieu, Catherine, Huffman, Jennifer E, Litkowski, Elizabeth, Liu, Chang, Ho, Yuk-Lam A, Hunter-Zinck, Haley, Zhao, Hongyu, Marouli, Eirini, North, Kari E, Lange, Ethan, Lange, Leslie A, Voight, Benjamin F, Gaziano, J Michael, Pyarajan, Saiju, Hauser, Elizabeth R, Tsao, Philip S, Wilson, Peter W F, Chang, Kyong-Mi, Cho, Kelly, O'Donnell, Christopher J, Sun, Yan V, Assimes, Themistocles L

“…Height has been associated with many clinical traits but whether such associations are causal versus secondary to confounding remains unclear in many cases. To…”
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