Search Results - "Kelly, William H."

Effect of Inhaled Glucocorticoids in Childhood on Adult Height by Kelly, H. William, Sternberg, Alice L, Lescher, Rachel, Fuhlbrigge, Anne L, Williams, Paul, Zeiger, Robert S, Raissy, Hengameh H, Van Natta, Mark L, Tonascia, James, Strunk, Robert C

“…Inhaled glucocorticoids are the recommended treatment for persistent childhood asthma. In a randomized, controlled trial, the use of inhaled budesonide in…”
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Assessing the therapeutic index of inhaled corticosteroids in children: Is knemometry the answer? by Kelly, H. William, PharmD

“…Since the introduction of topical inhaled corticosteroids (ICSs) for the treatment of asthma decades ago, there have been concerns about potential risks from…”
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Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial by Bacharier, Leonard B, Guilbert, Theresa W, Mauger, David T, Boehmer, Susan, Beigelman, Avraham, Fitzpatrick, Anne M, Jackson, Daniel J, Baxi, Sachin N, Benson, Mindy, Burnham, Carey-Ann D, Cabana, Michael, Castro, Mario, Chmiel, James F, Covar, Ronina, Daines, Michael, Gaffin, Jonathan M, Gentile, Deborah Ann, Holguin, Fernando, Israel, Elliot, Kelly, H. William, Lazarus, Stephen C, Lemanske, Robert F, Ly, Ngoc, Meade, Kelley, Morgan, Wayne, Moy, James, Olin, Tod, Peters, Stephen P, Phipatanakul, Wanda, Pongracic, Jacqueline A, Raissy, Hengameh H, Ross, Kristie, Sheehan, William J, Sorkness, Christine, Szefler, Stanley J, Teague, W. Gerald, Thyne, Shannon, Martinez, Fernando D

“…IMPORTANCE: Many preschool children develop recurrent, severe episodes of lower respiratory tract illness (LRTI). Although viral infections are often present,…”
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Asthma outcomes: Composite scores of asthma control by Cloutier, Michelle M., MD, Schatz, Michael, MD, MS, Castro, Mario, MD, MPH, Clark, Noreen, PhD, Kelly, H. William, PharmD, Mangione-Smith, Rita, MD, Sheller, James, MD, Sorkness, Christine, PharmD, Stoloff, Stuart, MD, Gergen, Peter, MD, MPH

“…Background Current asthma guidelines recommend assessing the level of a patient’s asthma control. Consequently, there is increasing use of asthma control as an…”
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Daily or Intermittent Budesonide in Preschool Children with Recurrent Wheezing by Zeiger, Robert S, Mauger, David, Bacharier, Leonard B, Guilbert, Theresa W, Martinez, Fernando D, Lemanske, Robert F, Strunk, Robert C, Covar, Ronina, Szefler, Stanley J, Boehmer, Susan, Jackson, Daniel J, Sorkness, Christine A, Gern, James E, Kelly, H. William, Friedman, Noah J, Mellon, Michael H, Schatz, Michael, Morgan, Wayne J, Chinchilli, Vernon M, Raissy, Hengameh H, Bade, Elizabeth, Malka-Rais, Jonathan, Beigelman, Avraham, Taussig, Lynn M

“…Guidelines suggest daily inhaled glucocorticoids in young children at high risk for asthma exacerbation. These investigators found that such treatment was not…”
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Comparison of Inhaled Corticosteroids: An Update by Kelly, H William

“…Objective: To review the basis for the estimated comparative daily dosages of inhaled corticosteroids for children and adults that are presented in the…”
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Inhaled corticosteroids in children: effects on bone mineral density and growth by Fuhlbrigge, Anne L, Dr, Kelly, H William, Prof

“…Summary Potent, topically active corticosteroids with minimum systemic activity have fewer adverse effects than do systemic corticosteroids, and can control…”
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Inhaled corticosteroid dosing: Double for nothing? by Kelly, H. William, PharmD

“…Two recent trials from the National Heart, Lung, and Blood Institute’s asthma clinical trials networks raise a concern about using double the dose of an…”
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Effect of Long-term Corticosteroid Use on Bone Mineral Density in Children: A Prospective Longitudinal Assessment in the Childhood Asthma Management Program (CAMP) Study by Kelly, H. William, Van Natta, Mark L, Covar, Ronina A, Tonascia, James, Green, Rebecca P, Strunk, Robert C, CAMP Research Group

“…Systemic corticosteroids are known to induce osteoporosis and increase the risk for fractures in adults and children. Inhaled corticosteroids have been shown…”
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Combined Analysis of Asthma Safety Trials of Long-Acting β2-Agonists by Busse, William W, Bateman, Eric D, Caplan, Arthur L, Kelly, H. William, O’Byrne, Paul M, Rabe, Klaus F, Chinchilli, Vernon M

“…In four clinical trials, the use of a long-acting β 2 -agonist plus an inhaled glucocorticoid did not result in a higher frequency of serious asthma events…”
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Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts by Park, Heung-Woo, MD, PhD, Ge, Bing, MSc, Tse, Szeman, MDCM, Grundberg, Elin, PhD, Pastinen, Tomi, MD, PhD, Kelly, H. William, PharmD, Tantisira, Kelan G., MD, MPH

“…Background Long-term intermittent oral corticosteroid (OCS) use in children with asthma leads to significant decreases in bone mineral accretion (BMA)…”
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Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing? by Beigelman, Avraham, MD, MSCI, King, Tonya S., PhD, Mauger, David, PhD, Zeiger, Robert S., MD, PhD, Strunk, Robert C., MD, Kelly, H. William, PharmD, Martinez, Fernando D., MD, Lemanske, Robert F., MD, Rivera-Spoljaric, Katherine, MD, MSCI, Jackson, Daniel J., MD, Guilbert, Theresa, MD, Covar, Ronina, MD, Bacharier, Leonard B., MD

“…Background Oral corticosteroids (OCSs) are recommended for severe wheezing episodes in children. However, limited evidence supports this intervention in…”
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Corticosteroid use and bone mineral accretion in children with asthma: Effect modification by vitamin D by Tse, Sze Man, MDCM, Kelly, H. William, PharmD, Litonjua, Augusto A., MD, MPH, Van Natta, Mark L., MHS, Weiss, Scott T., MD, MS, Tantisira, Kelan G., MD, MPH

“…Background The adverse effects of corticosteroids on bone mineral accretion (BMA) have been well documented. Vitamin D insufficiency, a prevalent condition in…”
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Rationale for the major changes in the pharmacotherapy section of the National Asthma Education and Prevention Program guidelines by Kelly, H. William, PharmD

“…Numerous changes have been incorporated into the new National Asthma Education and Prevention Program's Expert Panel Report 3. In the pharmacotherapy section…”
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Safety of small-particle inhaled corticosteroids in infants by Kelly, H. William, PharmD

“…The second trial was a 1-year comparison of ciclesonide HFA-MDI, 40 and 160 μg once daily, with placebo.6 Although it demonstrated no effect of ciclesonide on…”
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Alveolar nitric oxide concentration, small airways inflammation, and targeted asthma therapy: Are we there yet? by Kelly, H. William, PharmD

“…[...]there is currently no conclusive evidence that targeted therapy improves measures of small airways dysfunction, much less other significant clinical…”
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Ultrafine-Particle Inhalers, the Holy Grail of Inhaled Corticosteroid Therapy, or Not by Kelly, H. William, PharmD

“…ICSs work by stimulating glucocorticoid receptors within the lung to produce anti-inflammatory activity. [...]the greater airway delivery and improved…”
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The challenge of treating preschool wheezing episodes: The need for evidence-based approaches by Beigelman, Avraham, MD, MSCI, Zeiger, Robert S., MD, PhD, Kelly, H. William, PharmD, Bacharier, Leonard B., MD

“…With due diligence given to the limitations of post hoc analyses, we presented data suggesting that OCSs did not reduce symptom severity during acute…”
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Primary stenting for acute ischemic stroke using the Enterprise vascular reconstruction device: early results by Dumont, Travis M, Natarajan, Sabareesh K, Eller, Jorge L, Mocco, J, Kelly, Jr, William H, Snyder, Kenneth V, Hopkins, L Nelson, Siddiqui, Adnan H, Levy, Elad I

“…Primary stenting for acute ischemic stroke (AIS) using the Wingspan stent delivery system has been reported. Major technical limitations in that study were…”
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Risk of cataracts in the Childhood Asthma Management Program Cohort by Raissy, Hengameh H., PharmD, Sternberg, Alice L., ScM, Williams, Paul, MD, Jacobs, Aaron, MD, Kelly, H. William, PharmD

“…To the Editor: Use of systemic corticosteroids is a well-established risk factor for the development of posterior subcapsular cataracts (PSCs) in both children…”
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