Search Results - "Kelly, Neil Wrigley"
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Individuals with obesity who survive SARS‐CoV‐2 infection have preserved antigen‐specific T cell frequencies
Published in Obesity (Silver Spring, Md.) (01-10-2022)“…Objective Obesity is a major risk factor for severe disease in COVID‐19, with increased hospitalization, intensive care unit admission, and mortality. This…”
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Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time
Published in Nature communications (02-11-2023)“…SARS-CoV-2 neutralising antibodies provide protection against COVID-19. Evidence from early vaccine trials suggested binding antibody thresholds could serve as…”
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Obesity in HIV infection: host-pathogen interaction
Published in AIDS (London) (01-09-2022)“…Both obesity and HIV infection are characterized by a state of chronic inflammation associated with increased morbidity and mortality. This review aims to…”
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COVID-19 severity and obesity: are MAIT cells a factor?
Published in The lancet respiratory medicine (01-05-2021)Get full text
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Antigen specific T cells in people with obesity at five months following ChAdOx1 COVID-19 vaccination
Published in International Journal of Obesity (01-01-2023)“…Background/Objectives People with obesity (PWO) face an increased risk of severe outcomes from COVID-19, including hospitalisation, ICU admission and death…”
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Diagnosis of Tuberculosis with Molecular Methods and Treatment of Axial Skeleton Tuberculosis
Published in The Journal of the Royal College of Physicians of Edinburgh (01-12-2020)Get full text
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The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis
Published in Science signaling (18-04-2023)“…Mucosal-associated invariant T (MAIT) cells are an abundant population of innate T cells that recognize bacterial ligands and play a key role in host…”
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2356. Close correlation of RBD with Live Viral Neutralising Capacity Across Variants and Time Supports Use of RBD Thresholds to Predict Protective Host Immunity
Published in Open forum infectious diseases (27-11-2023)“…Abstract Background Although SARS-CoV-2 neutralising antibodies protect against severe COVID-19, whether circulating IgG titres reflect underlying host…”
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