Search Results - "Kelly, Mia N"
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Compensatory plasticity in diaphragm and intercostal muscle utilization in a rat model of ALS
Published in Experimental neurology (01-01-2018)“…In SOD1G93A transgenic rat model of ALS, breathing capacity is preserved until late in disease progression despite profound respiratory motor neuron (MN) cell…”
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2
Dose-dependent phosphorylation of endogenous Tau by intermittent hypoxia in rat brain
Published in Journal of applied physiology (1985) (01-09-2022)“…Intermittent hypoxia, or intermittent low oxygen interspersed with normal oxygen levels, has differential effects that depend on the "dose" of hypoxic episodes…”
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3
Attention to a threat‐related feature does not interfere with concurrent attentive feature selection
Published in Psychophysiology (01-06-2019)“…Visual features associated with a task and those that predict noxious events both prompt selectively heightened visuocortical responses. Conflicting views…”
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Circadian clock genes and respiratory neuroplasticity genes oscillate in the phrenic motor system
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2020)“…Circadian rhythms are endogenous and entrainable daily patterns of physiology and behavior. Molecular mechanisms underlie circadian rhythms, characterized by…”
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5
REM Sleep Rebound Following Acute Intermittent Hypoxia in Freely Behaving Rats
Published in The FASEB journal (01-05-2022)“…Core components of the circadian clock and molecules involved in neuroplasticity elicited by acute intermittent hypoxia (AIH) exhibit 24‐hour rhythms in gene…”
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Acute Intermittent Hypoxia Preconditioning Elicits Age and Sex‐Dependent Changes in Molecules Known to Regulate Phrenic Motor Plasticity
Published in The FASEB journal (01-05-2022)“…Acute intermittent hypoxia (AIH) elicits a form of respiratory motor plasticity known as phrenic long‐term facilitation (pLTF); preconditioning with daily AIH…”
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Closed-Loop, Cervical, Epidural Stimulation Elicits Respiratory Neuroplasticity after Spinal Cord Injury in Freely Behaving Rats
Published in eNeuro (01-01-2022)“…Over half of all spinal cord injuries (SCIs) are cervical, which can lead to paralysis and respiratory compromise, causing significant morbidity and mortality…”
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Magnitude and Mechanism of Phrenic Long-term Facilitation Shift Between Daily Rest Versus Active Phase
Published in Function (Oxford, England) (2023)“…Abstract Plasticity is a fundamental property of the neural system controlling breathing. One key example of respiratory motor plasticity is phrenic long-term…”
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Development of a Phrenic Nerve Injury Model in Rats to Study Axonal Regeneration and Compensatory Respiratory Neuroplasticity
Published in The FASEB journal (01-04-2020)“…Abstract only Phrenic nerve injury (PNI) is an unintended consequence of some clinical procedures, including heart and lung transplants. Injury can occur in…”
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10
Long Term Closed‐Loop Cervical Epidural Stimulation Elicits Plasticity in Diaphragm Motor Output
Published in The FASEB journal (01-04-2020)“…Abstract only More than half of traumatic spinal cord injuries (SCI) occur in the cervical region, leading to respiratory compromise and even failure. The…”
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DARPP‐32 and Cdk5 Expression in the Ventral Cervical Spinal Cord of Rats
Published in The FASEB journal (01-04-2019)“…Dopamine‐ and cAMP‐regulated phosphoprotein, 32 kDa (DARPP‐32) is a phosphatase that integrates complex neuronal information, including dopamine responsive…”
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12
Circadian Clock Gene Expression in Regions of Interest to Respiratory Control
Published in The FASEB journal (01-04-2019)“…Circadian rhythms are endogenous, ~24‐hour cycles that synchronize biological functions to external cues known as zeitgebers. Circadian rhythms emerge from…”
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Chronic, closed‐loop, cervical epidural stimulation elicits plasticity in diaphragm motor output and upregulates spinal neurotrophic factor gene expression
Published in The FASEB journal (01-04-2019)“…Electrical spinal stimulation after spinal cord injury (SCI) improves functional outcomes. However, there's an unmet need to understand if epidural stimulation…”
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14
Intermittent Hypoxia Differentially Modulates Endogenous Tau Phosphorylation in Rats
Published in The FASEB journal (01-04-2020)“…Abstract only Intermittent hypoxia, or periods of low oxygen, can have different effects depending on the dose of hypoxic episodes (duration, severity, number…”
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BDNF in Phrenic Motor Neurons: Effects of Cervical Spinal Injury and Intermittent Hypoxia
Published in The FASEB journal (01-04-2020)“…Abstract only Cervical spinal cord injury (cSCI) compromises breathing. Since respiratory impairment increases mortality, there is a critical need for new…”
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Long‐term Delivery of “Low Dose” Repetitive Intermittent Hypoxia is Not Associated with Detectable Pathology
Published in The FASEB journal (01-04-2018)“…Repetitive acute intermittent hypoxia (rAIH) is a promising therapeutic strategy to induce spinal plasticity and improve respiratory and non‐respiratory…”
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