Search Results - "Kelly, Lisa E"
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Nuclear Factor I in neurons, glia and during the formation of Müller glia‐derived progenitor cells in avian, porcine and primate retinas
Published in Journal of comparative neurology (1911) (01-06-2022)“…The regenerative potential of Müller glia (MG) is extraordinary in fish, poor in chick and terrible in mammals. In the chick model, MG readily reprogram into…”
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Gemcitabine Induces Microvesicle Particle Release in a Platelet-Activating Factor-Receptor-Dependent Manner via Modulation of the MAPK Pathway in Pancreatic Cancer Cells
Published in International journal of molecular sciences (21-12-2018)“…Studies, including ours, have shown that pro-oxidative stressors, such as chemotherapeutic agents, generate oxidized lipids with agonistic platelet-activating…”
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The Retinal Homeobox (Rx) gene is necessary for retinal regeneration
Published in Developmental biology (01-05-2011)“…The Retinal Homeobox (Rx) gene is essential for vertebrate eye development. Rx function is required for the specification and maintenance of retinal progenitor…”
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Autoregulation of retinal homeobox (rax) gene promoter activity through a highly conserved genomic element
Published in Genesis (New York, N.Y. : 2000) (01-11-2016)“…The Retinal homeobox (rax) gene is expressed in vertebrate retinal progenitor and stem cells and is essential for retinal development. In frogs, rax is…”
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Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product
Published in Developmental biology (15-03-2010)“…The retinal homeobox (Rx) gene product is essential for eye development. However little is known about its molecular function. It has been demonstrated that Rx…”
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Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina
Published in Molecular and cellular neuroscience (01-06-2024)“…Different kinase-dependent cell signaling pathways are known to play important roles in glia-mediated neuroprotection and reprogramming of Müller glia (MG)…”
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Regulation of retinal homeobox gene transcription by cooperative activity among cis-elements
Published in Gene (01-11-2010)“…The retinal homeobox ( Rx/rax) gene is essential for the development of the eye. Rax is among the earliest genes expressed during eye development, beginning in…”
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8
Keratinocyte-derived microvesicle particles mediate ultraviolet B radiation-induced systemic immunosuppression
Published in The Journal of clinical investigation (15-05-2021)“…A complete carcinogen, ultraviolet B (UVB) radiation (290-320 nm), is the major cause of skin cancer. UVB-induced systemic immunosuppression that contributes…”
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9
Chromatin access regulates the formation of Müller glia‐derived progenitor cells in the retina
Published in Glia (01-07-2023)“…Chromatin access and epigenetic control over gene expression play important roles in regulating developmental processes. However, little is known about how…”
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10
Thermal Burn Injury Generates Bioactive Microvesicles: Evidence for a Novel Transport Mechanism for the Lipid Mediator Platelet-Activating Factor (PAF) That Involves Subcellular Particles and the PAF Receptor
Published in The Journal of immunology (1950) (01-07-2020)“…Thermal burn injuries are an important environmental stressor that can result in considerable morbidity and mortality. The exact mechanism by which an…”
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Identification of retinal homeobox (rax) gene–dependent genes by a microarray approach: The DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway
Published in Developmental dynamics (01-11-2018)“…Background: The retinal homeobox (rx/rax) gene is a transcription factor expressed in the developing eye field that is necessary for normal eye development…”
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Enhanced Platelet-Activating Factor Synthesis Facilitates Acute and Delayed Effects of Ethanol-Intoxicated Thermal Burn Injury
Published in Journal of investigative dermatology (01-11-2018)“…Thermal burn injuries in patients who are alcohol-intoxicated result in greater morbidity and mortality. Murine models combining ethanol and localized thermal…”
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Xenopus laevis Nkx5.3 and sensory organ homeobox (SOHo) are expressed in developing sensory organs and ganglia of the head and anterior trunk
Published in Development genes and evolution (01-11-2016)“…Nkx5 family members are homeobox transcription factors important for sensory organ development. Several members of the Nkx5 family are expressed in the eye,…”
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miR‐199 plays both positive and negative regulatory roles in Xenopus eye development
Published in Genesis (New York, N.Y. : 2000) (01-03-2020)“…Summary To investigate microRNA (miR) functions in early eye development, we asked whether eye field transcription factors (EFTFs) are targets of miR‐dependent…”
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Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by vsx gene products
Published in Molecular vision (14-12-2016)“…The photoreceptor conserved element-1 (PCE-1) sequence is found in the transcriptional regulatory regions of many genes expressed in photoreceptors. The gene…”
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The Rx-like Homeobox Gene (Rx-L) Is Necessary for Normal Photoreceptor Development
Published in Investigative ophthalmology & visual science (01-10-2006)“…The retinal homeobox (Rx) gene plays an essential role in retinal development. An Rx-like (Rx-L) gene from Xenopus laevis has been identified. The purpose of…”
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Ocular forkhead transcription factors: seeing eye to eye
Published in The International journal of developmental biology (2009)“…Forkhead transcription factors comprise a large family of proteins with diverse functions during development. Recently, there has been accumulating evidence…”
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xArx2: An aristaless homolog that regulates brain regionalization during development in Xenopus laevis
Published in Genesis (New York, N.Y. : 2000) (01-01-2009)“…The aristaless‐related gene, Arx, plays a fundamental role in patterning the brain in humans and mice. Arx mutants exhibit lissencephaly among other anomalies…”
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Pbx1 and Meis1 regulate activity of the Xenopus laevis Zic3 promoter through a highly conserved region
Published in Biochemical and biophysical research communications (09-06-2006)“…Xenopus Zic3 (zinc finger in the cerebellum-3) is expressed in the dorsal neural tube of tailbud embryos and tadpoles. We have isolated a 3.1 kb DNA fragment…”
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Expression of the forkhead transcription factor FoxN4 in progenitor cells in the developing Xenopus laevis retina and brain
Published in Gene Expression Patterns (01-01-2007)“…Forkhead proteins are involved in gene regulation in a large variety of developmental situations. Several forkhead gene products are expressed in the…”
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