Search Results - "Kelly, John Daniel"
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Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: a mechanobiological model
Published in PloS one (24-07-2012)“…Extrinsic mechanical signals have been implicated as key regulators of mesenchymal stem cell (MSC) differentiation. It has been possible to test different…”
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Simulation of a balloon expandable stent in a realistic coronary artery—Determination of the optimum modelling strategy
Published in Journal of biomechanics (10-08-2010)“…Abstract Computational models of stent deployment in arteries have been widely used to shed light on various aspects of stent design and optimisation. In this…”
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Prone Positioning in Moderate to Severe Acute Respiratory Distress Syndrome Due to COVID-19: A Cohort Study and Analysis of Physiology
Published in Journal of intensive care medicine (01-02-2021)“…Background: Coronavirus disease 2019 (COVID-19) can lead to acute respiratory distress syndrome (ARDS) but it is unknown whether prone positioning improves…”
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ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study
Published in The Lancet (British edition) (29-08-2015)“…Summary Background At present, diagnosis of Ebola virus disease requires transport of venepuncture blood to field biocontainment laboratories for testing by…”
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The influence of plaque composition on underlying arterial wall stress during stent expansion: The case for lesion-specific stents
Published in Medical engineering & physics (01-05-2009)“…Abstract Intracoronary stent implantation is a mechanical procedure, the success of which depends to a large degree on the mechanical properties of each vessel…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection Cases Corroborated by Sequencing
Published in The American journal of tropical medicine and hygiene (01-10-2021)“…Evaluating cases of reinfection may offer some insight into areas for further investigation regarding durability of immune response to severe acute respiratory…”
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A Computational Model of Osteochondral Defect Repair Following Implantation of Stem Cell-Laden Multiphase Scaffolds
Published in Tissue engineering. Part A (01-01-2017)“…Developing successful tissue engineering strategies requires an understanding of how cells within an implanted scaffold interact with the host environment. The…”
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Mechanical Testing of Cartilage Constructs
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…A key goal of functional cartilage tissue engineering is to develop constructs with mechanical properties approaching those of the native tissue. Herein we…”
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Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells
Published in Journal of biomechanics (22-03-2010)“…Abstract Articular cartilage has a poor intrinsic capacity for self-repair. The advent of autologous chondrocyte implantation has provided a feasible method to…”
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Infrapatellar fat pad-derived stem cells maintain their chondrogenic capacity in disease and can be used to engineer cartilaginous grafts of clinically relevant dimensions
Published in Tissue engineering. Part A (01-11-2014)“…A therapy for regenerating large cartilaginous lesions within the articular surface of osteoarthritic joints remains elusive. While tissue engineering…”
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Antibiotic Prescription Patterns among Children Younger than 5 Years in Nouna District, Burkina Faso
Published in The American journal of tropical medicine and hygiene (01-05-2019)“…Understanding antibiotic use may help predict emergence of antimicrobial resistance. We evaluated antibiotic prescription trends in rural Burkina Faso, where…”
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Prevalence, Patterns, and Predictors of SARS-CoV-2 RNA and Culturable Virus in Tears of a Case-Ascertained Household Cohort
Published in American journal of ophthalmology (01-09-2024)“…To investigate the prevalence, patterns, and predictors of SARS-CoV-2 RNA and culturable virus in tears of a case-ascertained household cohort. Prospective,…”
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Assessing Onchocerciasis Subcriticality from Pre-Intervention Cross-Sectional Surveys
Published in The American journal of tropical medicine and hygiene (01-07-2020)“…Elimination of an infectious disease requires subcritical transmission, or a reproductive number less than one, and can be assessed with cross-sectional…”
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The Impact of Different Types of Violence on Ebola Virus Transmission During the 2018–2020 Outbreak in the Democratic Republic of the Congo
Published in The Journal of infectious diseases (15-12-2020)“…Abstract Background Our understanding of the different effects of targeted versus nontargeted violence on Ebola virus (EBOV) transmission in Democratic…”
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Substrate stiffness and oxygen availability as regulators of mesenchymal stem cell differentiation within a mechanically loaded bone chamber
Published in Biomechanics and modeling in mechanobiology (01-01-2015)“…Mechanical stimuli such as tissue deformation and fluid flow are often implicated as regulators of mesenchymal stem cell (MSC) differentiation during…”
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