Search Results - "Kelly, E. M."

Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks by McDermott, F. D., Heeney, A., Kelly, M. E., Steele, R. J., Carlson, G. L., Winter, D. C.

“…Background Anastomotic leak (AL) represents a dreaded complication following colorectal surgery, with a prevalence of 1–19 per cent. There remains a lack of…”
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Cannabinoid–Opioid Interaction in Chronic Pain by Abrams, D I, Couey, P, Shade, S B, Kelly, M E, Benowitz, N L

“…Cannabinoids and opioids share several pharmacologic properties and may act synergistically. The potential pharmacokinetics and the safety of the combination…”
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International retrospective study of the pipeline embolization device: a multicenter aneurysm treatment study by Kallmes, D F, Hanel, R, Lopes, D, Boccardi, E, Bonafé, A, Cekirge, S, Fiorella, D, Jabbour, P, Levy, E, McDougall, C, Siddiqui, A, Szikora, I, Woo, H, Albuquerque, F, Bozorgchami, H, Dashti, S R, Delgado Almandoz, J E, Kelly, M E, Turner, 4th, R, Woodward, B K, Brinjikji, W, Lanzino, G, Lylyk, P

“…Flow diverters are increasingly used in the endovascular treatment of intracranial aneurysms. Our aim was to determine neurologic complication rates following…”
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Meta‐analysis of the effect of extending the interval after long‐course chemoradiotherapy before surgery in locally advanced rectal cancer by Ryan, É. J., O'Sullivan, D. P., Kelly, M. E., Syed, A. Z., Neary, P. C., O'Connell, P. R., Kavanagh, D. O., Winter, D. C., O'Riordan, J. M.

“…Background The current standard of care in locally advanced rectal cancer (LARC) is neoadjuvant long‐course chemoradiotherapy (nCRT) followed by total…”
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Cannabis in painful HIV-associated sensory neuropathy : A randomized placebo-controlled trial by ABRAMS, D. I, JAY, C. A, SHADE, S. B, VIZOSO, H, REDA, H, PRESS, S, KELLY, M. E, ROWBOTHAM, M. C, PETERSEN, K. L

“…To determine the effect of smoked cannabis on the neuropathic pain of HIV-associated sensory neuropathy and an experimental pain model. Prospective randomized…”
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Management options for chronic anal fissure: a systematic review of randomised controlled trials by Boland, P. A., Kelly, M. E., Donlon, N. E., Bolger, J. C., Larkin, J. O., Mehigan, B. J., McCormick, P. H.

“…Introduction Anal fissure is the most common cause of severe anorectal pain in adults, contributing significantly to coloproctology workloads. There are a wide…”
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Direct label-free imaging of brain tissue using synchrotron light: a review of new spectroscopic tools for the modern neuroscientist by Pushie, M J, Kelly, M E, Hackett, M J

“…The incidence of brain disease and brain disorders is increasing on a global scale. Unfortunately, development of new therapeutic strategies has not increased…”
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Anti‐inflammatory effects of cannabinoid CB2 receptor activation in endotoxin‐induced uveitis by Toguri, J T, Lehmann, C, Laprairie, R B, Szczesniak, A M, Zhou, J, Denovan‐Wright, E M, Kelly, M E M

“…Background and Purpose Cannabinoid CB2 receptors mediate immunomodulation. Here, we investigated the effects of CB2 receptor ligands on leukocyte‐endothelial…”
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Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol‐dimethylheptyl at the type 1 and type 2 cannabinoid receptors by Tham, Mylyne, Yilmaz, Orhan, Alaverdashvili, Mariam, Kelly, Melanie E M, Denovan‐Wright, Eileen M, Laprairie, Robert B

“…Background and Purpose We sought to understand why (−)‐cannabidiol (CBD) and (−)‐cannabidiol‐dimethylheptyl (CBD‐DMH) exhibit distinct pharmacology, despite…”
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Experimental Cannabinoid 2 Receptor-Mediated Immune Modulation in Sepsis by Lehmann, Christian, Zhou, J., Kelly, M. E. M., Sardinha, J.

“…Sepsis is a complex condition that results from a dysregulated immune system in response to a systemic infection. Current treatments lack effectiveness in…”
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Prehabilitation in rectal surgery: a narrative review by Hannan, E., Kelly, M. E., Fahy, M. R., Winter, D. C.

“…Aim Neoadjuvant chemotherapy (NACRT) can make decompensated patients more vulnerable prior to rectal surgery. Prehabilitation is an intervention which enhances…”
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Lateral pelvic lymphadenectomy for low rectal cancer: a META-analysis of recurrence rates by Fahy, M. R., Kelly, M. E., Nugent, T., Hannan, E., Winter, D. C.

“…Background Locoregional recurrence (LR) remains a problem for patients with lower rectal cancer despite standardized surgery and improved neoadjuvant treatment…”
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The Endocannabinoid System as a Therapeutic Target in Glaucoma by Cairns, Elizabeth A., Kelly, M. E. M., Baldridge, William H.

“…Glaucoma is an irreversible blinding eye disease which produces progressive retinal ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only…”
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Outcomes following colonic stenting for malignant left-sided bowel obstruction: a systematic review of randomised controlled trials by Boland, Patrick Anthony, Kelly, M. E., Donlon, N. E., Rausa, E., Beddy, D. P., McCormick, P. H., Mehigan, B. J., Larkin, J. O.

“…Purpose Malignant bowel obstruction is a common presentation and is associated with high morbidity and mortality. Emergency resection is the traditional…”
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Epidemiology, Treatment Patterns and Survival in Canadian Patients With Chronic Hepatitis B‐Related Hepatocellular Carcinoma by Sachar, Y., Congly, S. E., Burak, K. W., Manko, A., Ko, H. H., Ramji, A., Rahman, H. S., Talia, J., Jeyaparan, J., Wong, D. W., Fung, S., Cooper, C., Kelly, E. M., Ma, M. M., Bailey, R., Minuk, G., Wong, A., Doucette, K., Elkashab, M., Sebastiani, G., Wong, P., Coffin, C. S., Brahmania, M.

“…ABSTRACT Chronic hepatitis B (CHB) is the leading cause of hepatocellular carcinoma (HCC) globally. We described and evaluated the outcomes of patients with…”
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A systematic review of stakeholder views of selection methods for medical schools admission by Kelly, M E, Patterson, F, O'Flynn, S, Mulligan, J, Murphy, A W

“…The purpose of this paper is to systematically review the literature with respect to stakeholder views of selection methods for medical school admissions. An…”
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Vaporization as a Smokeless Cannabis Delivery System: A Pilot Study by Abrams, D I, Vizoso, H P, Shade, S B, Jay, C, Kelly, M E, Benowitz, N L

“…Although cannabis may have potential therapeutic value, inhalation of a combustion product is an undesirable delivery system. The aim of the study was to…”
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Quality of life following ostomy reversal with purse-string vs linear skin closure: a systematic review by Rausa, Emanuele, Kelly, M. E., Sgroi, G., Lazzari, V., Aiolfi, A., Cavalcoli, F., Bonitta, G., Bonavina, L.

“…Background The importance of the defunctioning stoma on minimizing anastomotic leak in colorectal surgery is well established. However, a defunctioning stoma…”
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Synchronous colorectal liver metastasis: A network meta-analysis review comparing classical, combined, and liver-first surgical strategies by Kelly, M.E., Spolverato, G., Lê, G.N., Mavros, M.N., Doyle, F., Pawlik, T.M., Winter, D.C.

“…Background In recent years, the management of synchronous colorectal liver metastasis has changed significantly. Alternative surgical strategies to the…”
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Colonic stenting as a bridge to surgery in malignant large bowel obstruction: oncological outcomes by Donlon, N. E., Kelly, M. E., Narouz, F., McCormick, P. H., Larkin, J. O., Mehigan, B. J.

“…Introduction Stenting of obstructing colorectal cancers obviates the need for emergency surgery, reducing initial morbidity and mortality rate associated with…”
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