Search Results - "Kelly, DP"

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease by Finck, Brian N, Kelly, Daniel P

“…Members of the PPARgamma coactivator-1 (PGC-1) family of transcriptional coactivators serve as inducible coregulators of nuclear receptors in the control of…”
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Mitochondrial energy metabolism in heart failure: a question of balance by Huss, Janice M., Kelly, Daniel P.

“…The mitochondrion serves a critical role as a platform for energy transduction, signaling, and cell death pathways relevant to common diseases of the…”
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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function by Kelly, Daniel P, Scarpulla, Richard C

“…We are witnessing a period of renewed interest in the biology of the mitochondrion. The mitochondrion serves a critical function in the maintenance of cellular…”
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Nuclear Receptor Signaling and Cardiac Energetics by Huss, Janice M, Kelly, Daniel P

“…The heart has a tremendous capacity for ATP generation, allowing it to function as an efficient pump throughout the life of the organism. The adult myocardium…”
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The genome sequence of the obligately chemolithoautotrophic, facultatively anaerobic bacterium Thiobacillus denitfificans by Beller, H R, Larimer, Frank W

“…The complete genome sequence of Thiobacillus denitrificans ATCC 25259 is the first to become available for an obligately chemolithoautotrophic,…”
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PGC-1α Coactivates PDK4 Gene Expression via the Orphan Nuclear Receptor ERRα: a Mechanism for Transcriptional Control of Muscle Glucose Metabolism by Wende, Adam R., Huss, Janice M., Schaeffer, Paul J., Giguère, Vincent, Kelly, Daniel P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis by Leone, Teresa C, Lehman, John J, Finck, Brian N, Schaeffer, Paul J, Wende, Adam R, Boudina, Sihem, Courtois, Michael, Wozniak, David F, Sambandam, Nandakumar, Bernal-Mizrachi, Carlos, Chen, Zhouji, O. Holloszy, John, Medeiros, Denis M, Schmidt, Robert E, Saffitz, Jeffrey E, Abel, E. Dale, Semenkovich, Clay F, Kelly, Daniel P

“…The gene encoding the transcriptional coactivator peroxisome proliferator- activated receptor- coactivator-1 alpha (PGC-1 alpha ) was targeted in mice. PGC-1…”
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Materializing post-colonial geographies: examining the textural landscapes of migration in the South Asian home by Tolia-Kelly, Divya P.

“…This paper considers the role of visual cultures in understanding the value of landscape to post-colonial migrants living in Britain. The paper also considers…”
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The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes by Vega, Rick B., Huss, Janice M., Kelly, Daniel P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Critical Role for PPARα-Mediated Lipotoxicity in the Pathogenesis of Diabetic Cardiomyopathy: Modulation by Dietary Fat Content by Finck, Brian N., Han, Xianlin, Courtois, Michael, Aimond, Franck, Nerbonne, Jeanne M., Kovacs, Attila, Gross, Richard W., Kelly, Daniel P.

“…To explore the role of peroxisome proliferator-activated receptor $\alpha\>(PPAR\alpha)$-mediated derangements in myocardial metabolism in the pathogenesis of…”
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Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice by MIN YOU, CONSIDINE, Robert V, LEONE, Teresa C, KELLY, Daniel P, CRABB, David W

“…The protective effect of dietary saturated fatty acids against the development of alcoholic liver disease has long been known, but the underlying mechanism is…”
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Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1 by Baar, Keith, Wende, Adam R., Jones, Terry E., Marison, Matthew, Nolte, Lorraine A., Chen, May, Kelly, Daniel P., Holloszy, John O.

“…ABSTRACT Endurance exercise induces increases in mitochondria and the GLUT4 isoform of the glucose transporter in muscle. Although little is known about the…”
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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis by Lehman, J J, Barger, P M, Kovacs, A, Saffitz, J E, Medeiros, D M, Kelly, D P

“…Cardiac mitochondrial function is altered in a variety of inherited and acquired cardiovascular diseases. Recent studies have identified the transcriptional…”
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Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developmental Stage-Dependent Manner by Russell, Laurie K, Mansfield, Carolyn M, Lehman, John J, Kovacs, Attila, Courtois, Michael, Saffitz, Jeffrey E, Medeiros, Denis M, Valencik, Maria L, McDonald, John A, Kelly, Daniel P

“…ABSTRACT—Recent evidence has identified the peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) as a regulator of cardiac energy metabolism…”
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Reclassification of some species of Thiobacillus to the newly designated genera Acidithiobacillus gen. nov., Halothiobacillus gen. nov. and Thermithiobacillus gen. nov by Kelly, DP, Wood, AP

“…DP Kelly and AP Wood Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK The species of the genus 'Thiobacillus' fall into the…”
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A potential link between muscle peroxisome proliferator- activated receptor-α signaling and obesity-related diabetes by Finck, Brian N., Bernal-Mizrachi, Carlos, Han, Dong Ho, Coleman, Trey, Sambandam, Nandakumar, LaRiviere, Lori L., Holloszy, John O., Semenkovich, Clay F., Kelly, Daniel P.

“…The role of the peroxisome proliferator-activated receptor-α (PPARα) in the development of insulin-resistant diabetes was evaluated using gain- and…”
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Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-α-null hearts can be rescued by increasing glucose transport and utilization by LUPTAK, Ivan, BALSCHI, James A, YANQIU XING, LEONE, Teresa C, KELLY, Daniel P, RONG TIAN

“…Downregulation of peroxisome proliferator-activated receptor-alpha (PPARalpha) in hypertrophied and failing hearts leads to the reappearance of the fetal…”
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A Critical Role for the Peroxisome Proliferator-Activated Receptor α (PPARα) in the Cellular Fasting Response: The PPARα -Null Mouse as a Model of Fatty Acid Oxidation Disorders by Leone, Teresa C., Weinheimer, Carla J., Kelly, Daniel P.

“…We hypothesized that the lipid-activated transcription factor, the peroxisome proliferator-activated receptor α (PPARα), plays a pivotal role in the cellular…”
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Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy by Dávila-Román, Víctor G., Vedala, Giridhar, Herrero, Pilar, de las Fuentes, Lisa, Rogers, Joseph G., Kelly, Daniel P., Gropler, Robert J.

“…The purpose of this study was to determine whether patients with idiopathic dilated cardiomyopathy (IDCM) exhibit alterations in myocardial fatty acid and…”
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Fatty Acids Activate Transcription of the Muscle Carnitine Palmitoyltransferase I Gene in Cardiac Myocytes via the Peroxisome Proliferator-activated Receptor α by Brandt, Jon M., Djouadi, Fatima, Kelly, Daniel P.

“…To explore the gene regulatory mechanisms involved in the metabolic control of cardiac fatty acid oxidative flux, the expression of muscle-type carnitine…”
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