Search Results - "Kellokumpu, S"

The anion exchanger Ae2 is required for enamel maturation in mouse teeth by Lyaruu, D.M., Bronckers, A.L.J.J., Mulder, L., Mardones, P., Medina, J.F., Kellokumpu, S., Oude Elferink, R.P.J., Everts, V.

“…One of the mechanisms by which epithelial cells regulate intracellular pH is exchanging bicarbonate for Cl −. We tested the hypothesis that in ameloblasts the…”
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Comparison of laparoscopic and open colonic resection within fast-track and traditional perioperative care pathways: clinical outcomes and in-hospital costs by Ehrlich, A., Kellokumpu, S., Wagner, B., Kautiainen, H., Kellokumpu, I.

“…Background: This study examined short-term clinical outcomes and in-hospital costs of laparoscopic and open colonic resection within fast-track and traditional…”
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Sensitivity to Vanadate and Isoforms of Subunits A and B Distinguish the Osteoclast Proton Pump From Other Vacuolar H+ATPases by Chatterjee, D., Chakraborty, M., Leit, M., Neff, L., Jamsa-Kellokumpu, S., Fuchs, R., Baron, R.

“…Analysis of proton (H+) transport by inside-out vesicles derived from highly purified chicken osteoclast (OC) membranes has revealed the presence of a newly…”
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Identification of the Full-length AE2 (AE2a) Isoform as the Golgi-associated Anion Exchanger in Fibroblasts by Holappa, Katja, Suokas, Marko, Soininen, Paula, Kellokumpu, Sakari

“…SUMMARY Na+-independent Cl−/HCO3 − exchangers (AE1, AE2, AE3) are generally known as ubiquitous, multispanning plasma membrane proteins that regulate…”
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Mouse 17 beta-hydroxysteroid dehydrogenase type 2 mRNA is predominantly expressed in hepatocytes and in surface epithelial cells of the gastrointestinal and urinary tracts by Mustonen, MV, Poutanen, MH, Kellokumpu, S, de Launoit, Y, Isomaa, VV, Vihko, RK, Vihko, PT

“…17 beta-Hydroxysteroid dehydrogenase (17HSD) type 2 efficiently catalyzes the conversion of the high activity 17 beta-hydroxy forms of sex steroids into less…”
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Comparison of a peanut agglutinin test and an immunochemical faecal occult blood test in detecting colorectal neoplasia in symptomatic patients by Vironen, J., Kellokumpu, S., Andersson, L. C., Kellokumpu, I.

“…Background: Currently available methods for detection of early-stage colorectal cancer are reliant on faecal occult blood (FOB) tests. Bleeding, however, is…”
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Polarized expression of a band 3-related protein in mammalian sperm cells by PARKKILA, S, RAJANIEMI, H, KELLOKUMPU, S

“…Extracellular bicarbonate is known to be essential for sperm motility. This finding indirectly suggests that sperm cells possess a specific carrier protein,…”
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Lysyl hydroxylase, a collagen processing enzyme, exemplifies a novel class of luminally-oriented peripheral membrane proteins in the endoplasmic reticulum by Kellokumpu, S, Sormunen, R, Heikkinen, J, Myllylä, R

“…Lysyl hydroxylase (LH), an enzyme required early during collagen biosynthesis, appears to be exceptional among proteins that are thought to be residents of the…”
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A 115-kD Polypeptide Immunologically Related to Erythrocyte Band 3 is Present in Golgi Membranes by Kellokumpu, Sakari, Neff, Lynn, Jämsä-Kellokumpu, Sirpa, Kopito, Ron, Baron, Roland

“…Band 3 multigene family consists of several distinct but structurally related polypeptides which are probably involved in the transport of anions across the…”
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The osteoclast proton pump differs in its pharmacology and catalytic subunits from other vacuolar H(+)-ATPases by Chatterjee, D, Chakraborty, M, Leit, M, Neff, L, Jamsa-Kellokumpu, S, Fuchs, R, Bartkiewicz, M, Hernando, N, Baron, R

“…Osteoclasts are multinucleated cells derived from the mononuclear phagocyte system in the hematopoietic bone marrow. Their function is to resorb bone during…”
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Detection of colorectal neoplasia with peanut‐agglutinin(PNA)‐reactive carbohydrate structures in rectal mucus by Kellokumpu, Ilmo H., Andersson, Leif C., Kellokumpu, Sakari J.

“…In contrast to normal colorectal mucosa, peanut‐agglutinin(PNA)‐reactive glycoconjugates are commonly expressed in most colorectal carcinomas and in some…”
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Abnormal glycosylation and altered Golgi structure in colorectal cancer: dependence on intra-Golgi pH by Kellokumpu, Sakari, Sormunen, Raija, Kellokumpu, Ilmo

“…Abnormal glycosylation of cellular glycoconjugates is a common phenotypic change in many human tumors. Here, we explore the possibility that an altered Golgi…”
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Different processing of LH/hCG receptors in cultured rat luteal cells and murine Leydig tumour cells (MLTC-1) by Kellokumpu, S

“…The metabolic fate of LH/hCG receptors after exposure to human chorionic gonadotropin (hCG) was examined in cultured rat luteal cells and murine Leydig tumour…”
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A splice-site mutation that induces exon skipping and reduction in lysyl hydroxylase mRNA levels but does not create a nonsense codon in Ehlers-Danlos syndrome type VI by Pajunen, L, Suokas, M, Hautala, T, Kellokumpu, S, Tebbe, B, Kivirikko, K I, Myllylä, R

“…The type VI variant of Ehlers-Danlos syndrome (EDS) is a heritable connective tissue disorder caused by a deficiency in the activity of lysyl hydroxylase, an…”
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Purification and partial characterization of rat ovarian lutropin receptor by Keinänen, K P, Kellokumpu, S, Metsikkö, M K, Rajaniemi, H J

“…Lutropin (LH) receptor was solubilized from pseudopregnant rat ovaries and purified by two cycles of affinity chromatography on human choriogonadotropin…”
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Defective Acidification of Intracellular Organelles Results in Aberrant Secretion of Cathepsin D in Cancer Cells by Kokkonen, Nina, Rivinoja, Antti, Kauppila, Annika, Suokas, Marko, Kellokumpu, Ilmo, Kellokumpu, Sakari

“…Aberrant secretion of lysosomal hydrolases such as (pro)cathepsin D (proCD) is a common phenotypic change in many human cancers. Here we explore the underlying…”
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A high activity carbonic anhydrase isoenzyme (CA II) is present in mammalian spermatozoa by Parkkila, S, Kaunisto, K, Kellokumpu, S, Rajaniemi, H

“…Human and rat spermatozoa were stained for different carbonic anhydrase (CA) isoenzymes using specific antisera to human CA I, II and VI in conjunction with…”
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Visualization of the rat ovarian lutropin receptor by ligand blotting by Keinänen, K P, Kellokumpu, S, Rajaniemi, H J

“…A ligand blotting technique was developed to identify the lutropin receptor after size separation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis…”
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A 115-kD polypeptide immunologically related to erythrocytes band 3 is present in Golgi membranes by Kellokumpu, S, Neff, L, Jaemsae-Kellokumpu, S, Kopito, R, Baron, R

“…Band 3 multigene family consists of several distinct but structurally related polypeptides which are probably involved in the transport of anions across the…”
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Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues by Vaarala, Markku H., Porvari, Katja S., Kellokumpu, Sakari, Kyllönen, Atte P., Vihko, Pirkko T.

“…The purpose of this study was to clarify the expression of TMPRSS2 in mice during development and to compare the tissue distribution of the transcripts in…”
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