Search Results - "Kellinsalmi, Maarit"
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A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphonates
Published in British journal of pharmacology (01-02-2006)“…Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of diseases with excess bone resorption. On the basis of…”
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Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite
Published in Molecular pharmacology (01-05-2002)“…Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of diseases with excess bone resorption. Recent studies…”
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In vitro Comparison of Clodronate, Pamidronate and Zoledronic Acid Effects on Rat Osteoclasts and Human Stem Cell‐Derived Osteoblasts
Published in Basic & clinical pharmacology & toxicology (01-12-2005)“…: In the present study we compared the first generation non‐nitrogen‐containing bisphosphonate, clodronate with second and third generation nitrogen‐containing…”
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Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro
Published in European journal of pharmacology (31-10-2007)“…Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenases (COX) and are widely used for post-trauma musculoskeletal analgesia. In animal models,…”
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