Search Results - "Kelley, Ryan M."
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Conserved patterns of protein interaction in multiple species
Published in Proceedings of the National Academy of Sciences - PNAS (08-02-2005)“…To elucidate cellular machinery on a global scale, we performed a multiple comparison of the recently available protein-protein interaction networks of…”
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Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents
Published in Frontiers in psychology (05-04-2016)“…Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We…”
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Human subthalamic nucleus neurons differentially encode speech and limb movement
Published in Frontiers in human neuroscience (17-02-2023)“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN), which consistently improves limb motor functions, shows mixed effects on speech functions in…”
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Effect of deep brain stimulation on vocal motor control mechanisms in Parkinson's disease
Published in Parkinsonism & related disorders (01-06-2019)“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for limb motor symptoms in Parkinson's disease (PD); however, its…”
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Discovery Tactics To Mitigate Toxicity Risks Due to Reactive Metabolite Formation with 2-(2-Hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one Derivatives, Potent Calcium-Sensing Receptor Antagonists and Clinical Candidate(s) for the Treatment of Osteoporosis
Published in Chemical research in toxicology (21-06-2010)“…The synthesis and structure−activity relationship studies on 5-trifluoromethylpyrido[4,3-d]pyrimidin-4(3H)-ones as antagonists of the human calcium receptor…”
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Short-acting 5-(trifluoromethyl)pyrido[4,3- d]pyrimidin-4(3 H)-one derivatives as orally-active calcium-sensing receptor antagonists
Published in Bioorganic & medicinal chemistry letters (15-08-2009)“…Structure–activity relationship studies, focused on the optimization of pharmacology and pharmacokinetics, are described for a series of short-acting…”
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Metabolism, Pharmacokinetics, and Excretion of the 5-Hydroxytryptamine 1B Receptor Antagonist Elzasonan in Humans
Published in Drug metabolism and disposition (01-11-2010)Get full text
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5-Hydroxytryptamine1B Receptor Antagonist Elzasonan in Humans
Published in Drug metabolism and disposition (2010)Get full text
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Metabolism, pharmacokinetics, and excretion of the 5-hydroxytryptamine1b receptor antagonist elzasonan in humans
Published in Drug metabolism and disposition (01-11-2010)“…The metabolism, pharmacokinetics, and excretion of a potent and selective 5-hydroxytryptamine(1B) receptor antagonist elzasonan have been studied in six…”
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