Search Results - "Kellerman, Lior"

Differential roles for DNAJ isoforms in HTT-polyQ and FUS aggregation modulation revealed by chaperone screens by Rozales, Kinneret, Younis, Amal, Saida, Naseeb, Meller, Anatoly, Goldman, Hodaya, Kellerman, Lior, Heinrich, Ronit, Berlin, Shai, Shalgi, Reut

“…Protein aggregation is a hallmark of neurodegeneration. Here, we find that Huntington’s disease-related HTT-polyQ aggregation induces a cellular proteotoxic…”
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Observational cohort study of IP-10's potential as a biomarker to aid in inflammation regulation within a clinical decision support protocol for patients with severe COVID-19 by Lev, Shaul, Gottesman, Tamar, Sahaf Levin, Gal, Lederfein, Doron, Berkov, Evgeny, Diker, Dror, Zaidman, Aliza, Nutman, Amir, Ilan Ber, Tahel, Angel, Alon, Kellerman, Lior, Barash, Eran, Navon, Roy, Boico, Olga, Israeli, Yael, Rosenberg, Michal, Gelman, Amir, Kalfon, Roy, Simon, Einav, Avni, Noa, Hainrichson, Mary, Zarchin, Oren, Gottlieb, Tanya M, Oved, Kfir, Eden, Eran, Tadmor, Boaz

“…Treatment of severely ill COVID-19 patients requires simultaneous management of oxygenation and inflammation without compromising viral clearance. While…”
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The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species by Naaman, Efrat, Ya’ari, Sarah, Itzkovich, Chen, Safuri, Shadi, Macsi, Flora, Kellerman, Lior, Mimouni, Michael, Mann, Irit, Gazit, Ehud, Adler-Abramovich, Lihi, Zayit-Soudry, Shiri

“…Amyloid-β (Aβ), reported as a significant constituent of drusen, was implicated in the pathophysiology of age-related macular degeneration (AMD), yet the…”
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Cellular contractile forces are nonmechanosensitive by Feld, Lea, Kellerman, Lior, Mukherjee, Abhishek, Livne, Ariel, Bouchbinder, Eran, Wolfenson, Haguy

“…Cells' ability to apply contractile forces to their environment and to sense its mechanical properties (e.g., rigidity) are among their most fundamental…”
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426. Use of Real Time IP-10 Measurements to Identify and Monitor the Dysregulated Immune Response in COVID-19 Patients by Lev, Shaul, Gottesman, Tamar, Levin, Gal Shachaf, Ber, Tahel Ilan, Angel, Alon, Kellerman, Lior, Barash, Eran, Navon, Roy, Simon, Einav, Avni, Noa, Hainrichson, Mary, Gottlieb, Tanya, Oved, Kfir, Eden, Eran, Tadmor, Boaz

“…Abstract Background It is estimated that up to 10% of SARS-CoV-2 patients progress from early and pulmonary stages to the most severe stage of illness, which…”
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