Search Results - "Keller, Nicholas"

Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging by Berndsen, Zachary T., Keller, Nicholas, Grimes, Shelley, Jardine, Paul J., Smith, Douglas E.

“…Many viruses use molecular motors that generate large forces to package DNA to near-crystalline densities inside preformed viral proheads. Besides being a key…”
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Performing Artists' Perceptions on the Importance of Certified Athletic Trainers Through Production by Keller, Nicholas, Smith-Goodwin, Erika, Walker, Jennifer

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Evidence for an electrostatic mechanism of force generation by the bacteriophage T4 DNA packaging motor by Migliori, Amy D., Keller, Nicholas, Alam, Tanfis I., Mahalingam, Marthandan, Rao, Venigalla B., Arya, Gaurav, Smith, Douglas E.

“…How viral packaging motors generate enormous forces to translocate DNA into viral capsids remains unknown. Recent structural studies of the bacteriophage T4…”
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Restricted Mobility and Jamming of Densely Packed DNA Pulled Out from Phage Phi29 Virus Capsids by Fizari, Mounir, Keller, Nicholas A., Smith, Douglas E.

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Role of DNA–DNA sliding friction and nonequilibrium dynamics in viral genome ejection and packaging by Fizari, Mounir, Keller, Nicholas, Jardine, Paul J, Smith, Douglas E

“…Abstract Many viruses eject their DNA via a nanochannel in the viral shell, driven by internal forces arising from the high-density genome packing. The speed…”
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A Socio-Hydrological Assessment of Illinois Levee Systems by Keller, Nicholas

“…Recent inspections conducted on levee safety in the U.S. that participate in the United States Army Corps of Engineers (USACE) Levee Safety Program under…”
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High GC Content DNA does not Affect Phage T4 DNA Packaging -- Test of a Scrunchworm Model for Packaging Motor Function by Mo, Youbin, Keller, Nicholas A., Smith, Douglas E.

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Power-efficient in vivo brain-machine interfaces via brain-state estimation by Valencia, Daniel, Leone, Gianluca, Keller, Nicholas, Mercier, Patrick P, Alimohammad, Amir

“…Advances in brain-machine interfaces (BMIs) can potentially improve the quality of life of millions of users with spinal cord injury or other neurological…”
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Single DNA molecule jamming and history-dependent dynamics during motor-driven viral packaging by Keller, Nicholas, Grimes, Shelley, Jardine, Paul J., Smith, Douglas E.

“…The molecular motors that package DNA into viruses stall frequently under conditions promoting DNA–DNA attraction. Single-molecule experiments suggest the…”
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Agent-Based Modeling and Simulation of Child Maltreatment and Child Maltreatment Prevention by Hu, Xiaolin, Keller, Nicholas

“…This paper presents an agent-based model that simulates the dynamics of child maltreatment and child maltreatment prevention. The developed model follows the…”
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Repulsive DNA-DNA interactions accelerate viral DNA packaging in phage Phi29 by Keller, Nicholas, delToro, Damian, Grimes, Shelley, Jardine, Paul J, Smith, Douglas E

“…We use optical tweezers to study the effect of attractive versus repulsive DNA-DNA interactions on motor-driven viral packaging. Screening of repulsive…”
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Single-Molecule Measurements of Motor-Driven Viral DNA Packaging in Bacteriophages Phi29, Lambda, and T4 with Optical Tweezers by Keller, Nicholas, delToro, Damian J, Smith, Douglas E

“…Viral DNA packaging is a required step in the assembly of many dsDNA viruses. A molecular motor fueled by ATP hydrolysis packages the viral genome to near…”
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Function of a viral genome packaging motor from bacteriophage T4 is insensitive to DNA sequence by Mo, Youbin, Keller, Nicholas, delToro, Damian, Ananthaswamy, Neeti, Harvey, Stephen C, Rao, Venigalla B, Smith, Douglas E

“…Abstract Many viruses employ ATP-powered motors during assembly to translocate DNA into procapsid shells. Previous reports raise the question if motor function…”
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Continuous Allosteric Regulation of a Viral Packaging Motor by a Sensor that Detects the Density and Conformation of Packaged DNA by Berndsen, Zachary T., Keller, Nicholas, Smith, Douglas E.

“…We report evidence for an unconventional type of allosteric regulation of a biomotor. We show that the genome-packaging motor of phage ϕ29 is regulated by a…”
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Walker-A Motif Acts to Coordinate ATP Hydrolysis with Motor Output in Viral DNA Packaging by delToro, Damian, Ortiz, David, Ordyan, Mariam, Sippy, Jean, Oh, Choon-Seok, Keller, Nicholas, Feiss, Michael, Catalano, Carlos E., Smith, Douglas E.

“…During the assembly of many viruses, a powerful ATP-driven motor translocates DNA into a preformed procapsid. A Walker-A “P-loop” motif is proposed to…”
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Single Molecule Studies of the Effect of Spermidine on DNA Mechanics and Viral DNA Packaging by Keller, Nicholas A., Smith, Douglas E.

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Experimental comparison of forces resisting viral DNA packaging and driving DNA ejection by Keller, Nicholas, Berndsen, Zachary T, Jardine, Paul J, Smith, Douglas E

“…We compare forces resisting DNA packaging and forces driving DNA ejection in bacteriophage phi29 with theoretical predictions. Ejection of DNA from…”
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Single Molecule Dynamics of Viral DNA Packaging Using Optical Tweezers by Keller, Nicholas Andreas

“…Viral DNA packaging is a required step in the lytic cycle of many DNA viruses. A DNA polymer is packaged into a pre-formed capsid to a near crystalline density…”
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Data driven simulation modeling for mobile agent-based systems by Keller, Nicholas, Xiaolin Hu

“…Simulation modeling is generally knowledge-driven, where the models are developed based on knowledge about how the systems under study work. In this paper, we…”
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Curating Research Data - Cyber security perspective from a nascent Brain Machine Interface Laboratory by Pittman, Jason M., Bajwa, Garima, Joseph, Joshua, Keller, Nicholas

“…Researchers across disciplines are in dissonance between data curation and open access versus data security. To accelerate new discoveries, preserving…”
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