Search Results - "Keller, Margaux F."

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study by Pichler, Irene, Del Greco M, Fabiola, Gögele, Martin, Lill, Christina M, Bertram, Lars, Do, Chuong B, Eriksson, Nicholas, Foroud, Tatiana, Myers, Richard H, Nalls, Michael, Keller, Margaux F, Benyamin, Beben, Whitfield, John B, Pramstaller, Peter P, Hicks, Andrew A, Thompson, John R, Minelli, Cosetta

“…Although levels of iron are known to be increased in the brains of patients with Parkinson disease (PD), epidemiological evidence on a possible effect of iron…”
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Genome-wide analysis of the heritability of amyotrophic lateral sclerosis by Keller, Margaux F, Ferrucci, Luigi, Singleton, Andrew B, Tienari, Pentti J, Laaksovirta, Hannu, Restagno, Gabriella, Chiò, Adriano, Traynor, Bryan J, Nalls, Michael A

“…Considerable advances have been made in our understanding of the genetics underlying amyotrophic lateral sclerosis (ALS). Nevertheless, for the majority of…”
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Women in Combat Need a Collaborative Culture Shift by Brady, Elise, Keller, Margaux F

“…ABSTRACT The 2021 Women in Combat (WIC) Symposium brought together hundreds of service members, researchers, and multidisciplinary leaders for 3 days of…”
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Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI) by Nalls, Mike A., Keller, Margaux F., Hernandez, Dena G., Chen, Lan, Stone, David J., Singleton, Andrew B.

“…Background The Parkinson's Progression Marker Initiative is an international multicenter study whose main goal is investigating markers for Parkinson's disease…”
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Genetic risk and age in Parkinson's disease: Continuum not stratum by Nalls, Mike A., Escott-Price, Valentina, Williams, Nigel M., Lubbe, Steven, Keller, Margaux F., Morris, Huw R., Singleton, Andrew B.

“…Background Recent genomewide association study meta‐analyses have identified 28 loci associated with risk of Parkinson's disease (PD). We sought to investigate…”
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NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases by Nalls, Mike A, Bras, Jose, Hernandez, Dena G, Keller, Margaux F, Majounie, Elisa, Renton, Alan E, Saad, Mohamad, Jansen, Iris, Guerreiro, Rita, Lubbe, Steven, Plagnol, Vincent, Gibbs, J. Raphael, Schulte, Claudia, Pankratz, Nathan, Sutherland, Margaret, Bertram, Lars, Lill, Christina M, DeStefano, Anita L, Faroud, Tatiana, Eriksson, Nicholas, Tung, Joyce Y, Edsall, Connor, Nichols, Noah, Brooks, Janet, Arepalli, Sampath, Pliner, Hannah, Letson, Chris, Heutink, Peter, Martinez, Maria, Gasser, Thomas, Traynor, Bryan J, Wood, Nick, Hardy, John, Singleton, Andrew B

“…Abstract Our objective was to design a genotyping platform that would allow rapid genetic characterization of samples in the context of genetic mutations and…”
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Physical Health and Well-being: Updates and the Way Ahead by Phillips, Angela K, Keller, Margaux F, McClung, James P, Steele, Nancy, Witkop, Catherine T, Wu, T John

“…ABSTRACT Introduction The Women in Combat Summit 2021 “Forging the Future: How Women Enhance the Fighting Force” took place during February 9-11, 2021, via a…”
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Large C9orf72 repeat expansions are not a common cause of Parkinson's disease by Majounie, Elisa, Abramzon, Yevgeniya, Renton, Alan E, Keller, Margaux F, Traynor, Bryan J, Singleton, Andrew B

“…Abstract The concept of a pathological overlap between neurodegenerative disorders is gaining momentum. We sought to determine the contribution of C9orf72…”
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Physiology of Health and Performance: Enabling Success of Women in Combat Arms Roles by Dyches, Karmon D, Friedl, Karl E, Greeves, Julie P, Keller, Margaux F, McClung, Holly L, McGurk, Michael S, Popp, Kristin L, Teyhen, Deydre S

“…ABSTRACT Introduction The modern female soldier has yet to be fully characterized as she steps up to fill new combat roles that have only recently been opened…”
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Genetic comorbidities in Parkinson's disease by Nalls, Mike A, Saad, Mohamad, Noyce, Alastair J, Keller, Margaux F, Schrag, Anette, Bestwick, Jonathan P, Traynor, Bryan J, Gibbs, J Raphael, Hernandez, Dena G, Cookson, Mark R, Morris, Huw R, Williams, Nigel, Gasser, Thomas, Heutink, Peter, Wood, Nick, Hardy, John, Martinez, Maria, Singleton, Andrew B

“…Parkinson's disease (PD) has a number of known genetic risk factors. Clinical and epidemiological studies have suggested the existence of intermediate factors…”
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Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk by Moskvina, Valentina, Harold, Denise, Russo, GianCarlo, Vedernikov, Alexey, Sharma, Manu, Saad, Mohamed, Holmans, Peter, Bras, Jose M, Bettella, Francesco, Keller, Margaux F, Nicolaou, Nayia, Simón-Sánchez, Javier, Gibbs, J Raphael, Schulte, Claudia, Durr, Alexandra, Guerreiro, Rita, Hernandez, Dena, Brice, Alexis, Stefánsson, Hreinn, Majamaa, Kari, Gasser, Thomas, Heutink, Peter, Wood, Nick, Martinez, Maria, Singleton, Andrew B, Nalls, Michael A, Hardy, John, Owen, Michael J, O'Donovan, Michael C, Williams, Julie, Morris, Huw R, Williams, Nigel M

“…Despite Alzheimer disease (AD) and Parkinson disease (PD) being clinically distinct entities, there is a possibility of a pathological overlap, with some…”
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Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network by Chen, Zhao, Tang, Hua, Qayyum, Rehan, Schick, Ursula M, Nalls, Michael A, Handsaker, Robert, Li, Jin, Lu, Yingchang, Yanek, Lisa R, Keating, Brendan, Meng, Yan, van Rooij, Frank J A, Okada, Yukinori, Kubo, Michiaki, Rasmussen-Torvik, Laura, Keller, Margaux F, Lange, Leslie, Evans, Michele, Bottinger, Erwin P, Linderman, Michael D, Ruderfer, Douglas M, Hakonarson, Hakon, Papanicolaou, George, Zonderman, Alan B, Gottesman, Omri, Thomson, Cynthia, Ziv, Elad, Singleton, Andrew B, Loos, Ruth J F, Sleiman, Patrick M A, Ganesh, Santhi, McCarroll, Steven, Becker, Diane M, Wilson, James G, Lettre, Guillaume, Reiner, Alexander P

“…Laboratory red blood cell (RBC) measurements are clinically important, heritable and differ among ethnic groups. To identify genetic variants that contribute…”
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Assessment of Parkinson's disease risk loci in Greece by Kara, Eleanna, Xiromerisiou, Georgia, Spanaki, Cleanthe, Bozi, Maria, Koutsis, Georgios, Panas, Marios, Dardiotis, Efthimios, Ralli, Styliani, Bras, Jose, Letson, Christopher, Edsall, Connor, Pliner, Hannah, Arepalli, Sampath, Kalinderi, Kallirhoe, Fidani, Liana, Bostantjopoulou, Sevasti, Keller, Margaux F, Wood, Nicholas W, Hardy, John, Houlden, Henry, Stefanis, Leonidas, Plaitakis, Andreas, Hernandez, Dena, Hadjigeorgiou, Georgios M, Nalls, Mike A, Singleton, Andrew B

“…Abstract Genome-wide association studies (GWAS) have been shown to be a powerful approach to identify risk loci for neurodegenerative diseases. Recent GWAS in…”
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Correction: Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study by Pichler, Irene, Del Greco M., Fabiola, Gögele, Martin, Lill, Christina M., Bertram, Lars, Do, Chuong B., Eriksson, Nicholas, Foroud, Tatiana, Myers, Richard H., Nalls, Michael, Keller, Margaux F., Benyamin, Beben, Whitfield, John B., Pramstaller, Peter P., Hicks, Andrew A., Thompson, John R., Minelli, Cosetta

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease by Nalls, Mike A, Pankratz, Nathan, Lill, Christina M, Do, Chuong B, Hernandez, Dena G, Saad, Mohamad, DeStefano, Anita L, Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F, Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H, Cheng, Rong, Ikram, M Arfan, Ioannidis, John P A, Hadjigeorgiou, Georgios M, Bis, Joshua C, Martinez, Maria, Perlmutter, Joel S, Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H, Clark, Lorraine N, Stefansson, Kari, Hardy, John A, Heutink, Peter, Chen, Honglei, Wood, Nicholas W, Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B

“…Andrew Singleton and colleagues report a large-scale meta-analysis of genome-wide association data in Parkinson's disease using over 13,000 cases and 95,000…”
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Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study by Nalls, Mike A, PhD, McLean, Cory Y, PhD, Rick, Jacqueline, PhD, Eberly, Shirley, MS, Hutten, Samantha J, PhD, Gwinn, Katrina, MD, Sutherland, Margaret, PhD, Martinez, Maria, PhD, Heutink, Peter, PhD, Williams, Nigel M, PhD, Hardy, John, PhD, Gasser, Thomas, MD, Brice, Alexis, MD, Price, T Ryan, MS, Nicolas, Aude, PhD, Keller, Margaux F, PhD, Molony, Cliona, PhD, Gibbs, J Raphael, MS, Chen-Plotkin, Alice, MD, Suh, Eunran, PhD, Letson, Christopher, BS, Fiandaca, Massimo S, MD, Mapstone, Mark, PhD, Federoff, Howard J, MD, Noyce, Alastair J, MRCP, Morris, Huw, MD, Van Deerlin, Vivianna M, MD, Weintraub, Daniel, MD, Zabetian, Cyrus, MD, Hernandez, Dena G, MS, Lesage, Suzanne, PhD, Mullins, Meghan, BA, Conley, Emily Drabant, PhD, Northover, Carrie A M, PhD, Frasier, Mark, PhD, Marek, Ken, MD, Day-Williams, Aaron G, PhD, Stone, David J, PhD, Ioannidis, John P A, Prof, Singleton, Andrew B, Dr

“…Summary Background Accurate diagnosis and early detection of complex diseases, such as Parkinson's disease, has the potential to be of great benefit for…”
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Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations by Fox, Ervin, Edwards, Todd L., Nalls, Michael A., Tayo, Bamidele O., Adeyemo, Adebawole, Young, J. Hunter, Duan, Qing, Chen, Fang, Li, Yun, Fornage, Myriam, Keene, Keith L., Andrews, Jeanette S., Smith, Jennifer A., Faul, Jessica D., Liu, Yu, Murray, Sarah S., Musani, Solomon K., Srinivasan, Sathanur, Velez Edwards, Digna R., Wang, Heming, Bovet, Pascal, Bochud, Murielle, Broeckel, Ulrich, Burnier, Michel, Chasman, Daniel I., Ehret, Georg, Chen, Wei-Min, Chen, Wei, Dreisbach, Albert W., Evans, Michele K., Guo, Xiuqing, Garcia, Melissa E., Jensen, Rich, Lettre, Guillaume, Lotay, Vaneet, Martin, Lisa W., Moore, Jason H., Morrison, Alanna C., Mosley, Thomas H., Penman, Alan, Polak, Joseph F., Ridker, Paul M., Salako, Babatunde, Singleton, Andrew B., Shriner, Daniel, Taylor, Kent D., Wiggins, Kerri, Williams, Scott M., Yanek, Lisa R., Zonderman, Alan B., Becker, Diane M., Berenson, Gerald, Boerwinkle, Eric, Bottinger, Erwin, Nyberg, Fredrik, Heiss, Gerardo, Howard, Virginia J., Liu, Kiang, Liu, Yongmei, Loos, Ruth, Snyder, Michael, Go, Min Jin, Kim, Young Jin, Lee, Jong-Young, Jeon, Jae-Pil, Han, Bok-Ghee, Cho, Yoon Shin, Tay, Wan Ting, Ong, Rick Twee Hee, Seielstad, Mark, Aung, Tin, Wong, Tien Yin, Tai, E. Shyong, Chang, Li-ching, Wu, Jer-Yuarn, Kelly, Tanika N., Hixson, James E., Sung, Yun Ju, Kato, Norihiro, Takeuchi, Fumihiko, Sugiyama, Takao, Zhang, Yi, Huang, Wei, Zhou, Xueya, Jin, Li, Zhu, Dingliang, Schork, Nicholas J., Weir, David R., Harris, Tamara, Hunt, Steven C., Arnett, Donna, Redline, Susan, Cooper, Richard S., Risch, Neil J., Rotter, Jerome I., Chakravarti, Aravinda, Reiner, Alex P., Levy, Daniel, Keating, Brendan J., Zhu, Xiaofeng

“…High blood pressure (BP) is more prevalent and contributes to more severe manifestations of cardiovascular disease (CVD) in African Americans than in any other…”
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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin by Liu, Ching-Ti, Raghavan, Sridharan, Maruthur, Nisa, Kabagambe, Edmond Kato, Hong, Jaeyoung, Hivert, Marie-France, Lu, Yingchang, Bentley, Amy R., Drolet, Anne M., Gaulton, Kyle J., Guo, Xiuqing, Armstrong, Loren L., Irvin, Marguerite R., Li, Man, Rybin, Denis V., Agyemang, Charles, Palmer, Nicholette D., Cade, Brian E., Chen, Wei-Min, Dauriz, Marco, Delaney, Joseph A.C., Edwards, Todd L., Lange, Leslie A., Leong, Aaron, Liu, Jingmin, Liu, Yongmei, Nayak, Uma, Patel, Sanjay R., Rasmussen-Torvik, Laura J., Snijder, Marieke B., Stallings, Sarah C., Tanaka, Toshiko, Yanek, Lisa R., Becker, Diane M., Bielak, Lawrence F., Biggs, Mary L., Chen, Guanjie, Correa, Adolfo, Couper, David J., Crawford, Dana C., Cushman, Mary, Eicher, John D., Fornage, Myriam, Franceschini, Nora, Fu, Yi-Ping, Goodarzi, Mark O., Gottesman, Omri, Harris, Tamara B., Jensen, Richard A., Jhun, Min A., Karter, Andrew J., Keller, Margaux F., Kho, Abel N., Kizer, Jorge R., Krauss, Ronald M., Langefeld, Carl D., Li, Xiaohui, Liang, Jingling, Liu, Simin, Lowe, William L., Mosley, Thomas H., North, Kari E., Pacheco, Jennifer A., Peyser, Patricia A., Patrick, Alan L., Rice, Kenneth M., Selvin, Elizabeth, Sims, Mario, Tajuddin, Salman M., Vaidya, Dhananjay, Wren, Mary P., Yao, Jie, Ziegler, Julie T., Zmuda, Joseph M., Zonderman, Alan B., Zwinderman, Aeilko H., Adeyemo, Adebowale, Boerwinkle, Eric, Ferrucci, Luigi, Hayes, M. Geoffrey, Kardia, Sharon L.R., Miljkovic, Iva, Pankow, James S., Rotimi, Charles N., Sale, Michele M., Wagenknecht, Lynne E., Arnett, Donna K., Chen, Yii-Der Ida, Province, Michael A., Kao, W.H. Linda, Siscovick, David S., Psaty, Bruce M., Wilson, James G., Loos, Ruth J.F., Dupuis, Josée, Rich, Stephen S., Florez, Jose C., Rotter, Jerome I., Morris, Andrew P., Meigs, James B.

“…Knowledge of the genetic basis of the type 2 diabetes (T2D)-related quantitative traits fasting glucose (FG) and insulin (FI) in African ancestry (AA)…”
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Genetic risk and age in Parkinson’s: continuum not stratum by Nalls, Mike A., Escott-Price, Valentina, Williams, Nigel, Lubbe, Steven, Keller, Margaux F., Morris, Huw R., Singleton, Andrew B.

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Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians12 by Fretts, Amanda M, Follis, Jack L, Nettleton, Jennifer A, Lemaitre, Rozenn N, Ngwa, Julius S, Wojczynski, Mary K, Kalafati, Ioanna Panagiota, Varga, Tibor V, Frazier-Wood, Alexis C, Houston, Denise K, Lahti, Jari, Ericson, Ulrika, van den Hooven, Edith H, Mikkilä, Vera, Kiefte-de Jong, Jessica C, Mozaffarian, Dariush, Rice, Kenneth, Renström, Frida, North, Kari E, McKeown, Nicola M, Feitosa, Mary F, Kanoni, Stavroula, Smith, Caren E, Garcia, Melissa E, Tiainen, Anna-Maija, Sonestedt, Emily, Manichaikul, Ani, van Rooij, Frank JA, Dimitriou, Maria, Raitakari, Olli, Pankow, James S, Djoussé, Luc, Province, Michael A, Hu, Frank B, Lai, Chao-Qiang, Keller, Margaux F, Perälä, Mia-Maria, Rotter, Jerome I, Hofman, Albert, Graff, Misa, Kähönen, Mika, Mukamal, Kenneth, Johansson, Ingegerd, Ordovas, Jose M, Liu, Yongmei, Männistö, Satu, Uitterlinden, André G, Deloukas, Panos, Seppälä, Ilkka, Psaty, Bruce M, Cupples, L Adrienne, Borecki, Ingrid B, Franks, Paul W, Arnett, Donna K, Nalls, Mike A, Eriksson, Johan G, Orho-Melander, Marju, Franco, Oscar H, Lehtimäki, Terho, Dedoussis, George V, Meigs, James B, Siscovick, David S

“…Background: Recent studies suggest that meat intake is associated with diabetes-related phenotypes. However, whether the associations of meat intake and…”
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