Search Results - "Keller, Amanda R"

Increased Actin Binding Is a Shared Molecular Consequence of Numerous SCA5 Mutations in β-III-Spectrin by Atang, Alexandra E, Keller, Amanda R, Denha, Sarah A, Avery, Adam W

“…Spinocerebellar ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the SPTBN2 gene encoding the cytoskeletal protein β-III-spectrin…”
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Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5 by Guhathakurta, Piyali, Rebbeck, Robyn T., Denha, Sarah A., Keller, Amanda R., Carter, Anna L., Atang, Alexandra E., Svensson, Bengt, Thomas, David D., Hays, Thomas S., Avery, Adam W.

“…β-III-Spectrin is a key cytoskeletal protein that localizes to the soma and dendrites of cerebellar Purkinje cells and is required for dendritic arborization…”
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Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration by Farooq, Hasan, Luehmann, Hannah P., Koenitzer, Jeffrey R., Heo, Gyu Seong, Sultan, Deborah H., Kulkarni, Devesha H., Gunsten, Sean P., Sashti, Rekha M., Huang, Tao, Keller, Amanda R., Lavine, Kory J., Atkinson, Jeffrey J., Wingler, Laura M., Liu, Yongjian, Brody, Steven L.

“…Pulmonary fibrosis is a challenging clinical problem with lung pathology featuring immune cell infiltrates, fibroblast expansion, and matrix deposition…”
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Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltrationResearch in context by Hasan Farooq, Hannah P. Luehmann, Jeffrey R. Koenitzer, Gyu Seong Heo, Deborah H. Sultan, Devesha H. Kulkarni, Sean P. Gunsten, Rekha M. Sashti, Tao Huang, Amanda R. Keller, Kory J. Lavine, Jeffrey J. Atkinson, Laura M. Wingler, Yongjian Liu, Steven L. Brody

“…Background: Pulmonary fibrosis is a challenging clinical problem with lung pathology featuring immune cell infiltrates, fibroblast expansion, and matrix…”
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