Search Results - "Kelleher, Zachary"
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NOS2 Regulation of NF-κB by S-Nitrosylation of p65
Published in The Journal of biological chemistry (19-10-2007)“…Signal transduction in the NF-κB transcription factor pathway is inhibited by inducible nitric oxide synthase (NOS2) activity, although the molecular…”
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Endothelial LAT1 (SLC7A5) Mediates S-Nitrosothiol Import and Modulates Respiratory Sequelae of Red Blood Cell Transfusion In Vivo
Published in Thrombosis and haemostasis (01-07-2024)“…Increased adhesivity of red blood cells (RBCs) to endothelial cells (ECs) may contribute to organ dysfunction in malaria, sickle cell disease, and diabetes…”
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Thioredoxin-mediated Denitrosylation Regulates Cytokine-induced Nuclear Factor κB (NF-κB) Activation
Published in The Journal of biological chemistry (31-01-2014)“…S-nitrosylation of nuclear factor κB (NF-κB) on the p65 subunit of the p50/p65 heterodimer inhibits NF-κB DNA binding activity. We have recently shown that p65…”
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ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity
Published in The Journal of biological chemistry (06-09-2019)“…Dynamic control of thioredoxin (Trx) oxidoreductase activity is essential for balancing the need of cells to rapidly respond to oxidative/nitrosative stress…”
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Protection from Lipopolysaccharide-induced Lung Injury by Augmentation of Airway S-Nitrosothiols
Published in American journal of respiratory and critical care medicine (01-07-2009)“…S-Nitrosothiols (SNO) inhibit immune activation of the respiratory epithelium and airway SNO levels are decreased in inflammatory lung disease. Ethyl nitrite…”
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Epstein-Barr-based episomal chromosomes shuttle 100 kb of self-replicating circular human DNA in mouse cells
Published in Nature biotechnology (01-08-1998)“…We describe the microcell fusion transfer of 100-200 kb self-replicating circular human minichromosomes from human into mouse cells. This experimental approach…”
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Oral 1811-1 - Thioredoxin-interacting protein (Txnip) regulates thioredoxin-mediated NF-κB denitrosylation and activation in the respiratory epithelium
Published in Nitric oxide (15-11-2014)Get full text
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Thioredoxin-interacting protein (Txnip) regulates thioredoxin-mediated NF-κB denitrosylation and activation in the respiratory epithelium
Published in Nitric oxide (01-11-2014)Get full text
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9
Thioredoxin regulates NF-kappa B activity through cytokine-mediated denitrosylation of p65
Published in Nitric oxide (15-07-2012)“…Activation of the pro-inflammatory transcription factor NF-Kappa B (p50–p65) is inhibited via S-nitrosylation of the p65 subunit (SNO-p65). In the respiratory…”
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NOS2 regulation of LPS-induced airway inflammation via S-nitrosylation of NF-{kappa}B p65
Published in American journal of physiology. Lung cellular and molecular physiology (01-09-2011)“…Inducible nitric oxide synthase (NOS2) expression is increased in the airway epithelium in acute inflammatory disorders although the physiological impact…”
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Abstract 16464: Adhesion Receptors Mediating the LAT1-Sensitive Adhesion of Red Blood Cells to Endothelial Cells
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionNitric oxide (NO) modulates the adhesivity of RBCs to endothelial cells (ECs), which may interfere with blood respiratory function and promote…”
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12
NOS2 regulation of NF-kappaB by S-nitrosylation of p65
Published in The Journal of biological chemistry (19-10-2007)“…Signal transduction in the NF-kappaB transcription factor pathway is inhibited by inducible nitric oxide synthase (NOS2) activity, although the molecular…”
Get full text
Journal Article -
13
NOS2 Regulation of NF-κB by S-Nitrosylation of p65
Published in The Journal of biological chemistry (19-10-2007)“…Signal transduction in the NF-κB transcription factor pathway is inhibited by inducible nitric oxide synthase (NOS2) activity, although the molecular…”
Get full text
Journal Article