Search Results - "Kelleher, S."

Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing by Kelleher, Erin S

“…Transposable elements (TEs) are both important drivers of genome evolution and genetic parasites with potentially dramatic consequences for host fitness. The…”
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Cicada Wing Surface Topography: An Investigation into the Bactericidal Properties of Nanostructural Features by Kelleher, S. M, Habimana, O, Lawler, J, O’ Reilly, B, Daniels, S, Casey, E, Cowley, A

“…Recently, the surface of the wings of the Psaltoda claripennis cicada species has been shown to possess bactericidal properties and it has been suggested that…”
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Genetic variation in P-element dysgenic sterility is associated with double-strand break repair and alternative splicing of TE transcripts by Lama, Jyoti, Srivastav, Satyam, Tasnim, Sadia, Hubbard, Donald, Hadjipanteli, Savana, Smith, Brittny R, Macdonald, Stuart J, Green, Llewellyn, Kelleher, Erin S

“…The germline mobilization of transposable elements (TEs) by small RNA mediated silencing pathways is conserved across eukaryotes and critical for ensuring the…”
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Retrotransposons: Stowaways in the Primordial Germline by Kelleher, Erin S.

“…In order to succeed, retrotransposon transcripts must identify the subset of nuclei that will be transmitted to offspring. A new study reveals that the…”
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Etiologies of NICU deaths by Jacob, Jack, Kamitsuka, Michael, Clark, Reese H, Kelleher, Amy S, Spitzer, Alan R

“…Infant mortality is an indicator of overall societal health, and a significant proportion of infant deaths occur in NICUs. The objectives were to identify…”
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Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity by Wang, Luyang, Barbash, Daniel A, Kelleher, Erin S

“…In metazoan germlines, the piRNA pathway acts as a genomic immune system, employing small RNA-mediated silencing to defend host DNA from the harmful effects of…”
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Analysis of piRNA-mediated silencing of active TEs in Drosophila melanogaster suggests limits on the evolution of host genome defense by Kelleher, Erin S, Barbash, Daniel A

“…The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing…”
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Drosophila interspecific hybrids phenocopy piRNA-pathway mutants by Kelleher, Erin S, Edelman, Nathaniel B, Barbash, Daniel A

“…The Piwi-interacting RNA (piRNA) pathway defends the germline of animals from the deleterious activity of selfish transposable elements (TEs) through small-RNA…”
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QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline by Kelleher, Erin S, Jaweria, Jaweria, Akoma, Uchechukwu, Ortega, Lily, Tang, Wenpei

“…Transposable elements (TEs) are obligate genetic parasites that propagate in host genomes by replicating in germline nuclei, thereby ensuring transmission to…”
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Emergency physician focused cardiac ultrasound improves diagnosis of ascending aortic dissection by Pare, Joseph R., MD, Liu, Rachel, MD, Moore, Christopher L., MD, Sherban, Tyler, BA, Kelleher, Michael S., MD, Thomas, Sheeja, MD, Taylor, R. Andrew, MD, MHS

“…Abstract Study Objective Ascending aortic dissection (AAD) is an uncommon, time-sensitive, and deadly diagnosis with a nonspecific presentation. Ascending…”
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Paternal Induction of Hybrid Dysgenesis in Drosophila melanogaster Is Weakly Correlated with Both P -Element and hobo Element Dosage by Srivastav, Satyam P, Kelleher, Erin S

“…Transposable elements (TEs) are virtually ubiquitous components of genomes, yet they often impose significant fitness consequences on their hosts. In addition…”
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Gestational age and age at sampling influence metabolic profiles in premature infants by Clark, Reese H, Kelleher, Amy S, Chace, Donald H, Spitzer, Alan R

“…To describe the influence that gestational age and chronological age have on amino acid and acylcarnitine profiles in an at-risk population of premature…”
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Postmating transcriptional changes in reproductive tracts of con- and heterospecifically mated Drosophila mojavensis females by Bono, Jeremy M, Matzkin, Luciano M, Kelleher, Erin S, Markow, Therese A

“…In internally fertilizing organisms, mating involves a series of highly coordinated molecular interactions between the sexes that occur within the female…”
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Elucidating the clinical characteristics of patients captured using different definitions of massive transfusion by Zatta, A. J., McQuilten, Z. K., Mitra, B., Roxby, D. J., Sinha, R., Whitehead, S., Dunkley, S., Kelleher, S., Hurn, C., Cameron, P. A., Isbister, J. P., Wood, E. M., Phillips, L. E.

“…Background and Objectives The type and clinical characteristics of patients identified with commonly used definitions of massive transfusion (MT) are largely…”
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Blood Testosterone Threshold for Androgen Deficiency Symptoms by Kelleher, S., Conway, A. J., Handelsman, D. J.

“…There are few systematic studies of the relationship between blood testosterone concentrations and the symptoms of overt androgen deficiency. Because most…”
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Cognitive problems following hematopoietic stem cell transplant: relationships with sleep, depression and fatigue by Ghazikhanian, S E, Dorfman, C S, Somers, T J, O'Sullivan, M L, Fisher, H M, Edmond, S N, Wren, A A, Kelleher, S A, Rowe Nichols, K A, Chao, N, Shelby, R A

“…Cognitive problems are a significant, persistent concern for patients undergoing hematopoietic stem cell transplant (HSCT). Sleep is important for many…”
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Targeted identification of TE insertions in a Drosophila genome through hemi-specific PCR by Zhang, Shuo, Kelleher, Erin S

“…Transposable elements (TEs) are major components of eukaryotic genomes and drivers of genome evolution, producing intraspecific polymorphism and interspecific…”
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Jack of all trades versus master of one: how generalist versus specialist strategies of transposable elements relate to their horizontal transfer between lineages by Kelleher, Erin S

“…Transposable elements (TEs) are obligate genomic parasites, relying on host germline cells to ensure their replication and passage to future generations. While…”
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Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats by Ke, X, Lei, Q, James, S. J, Kelleher, S. L, Melnyk, S, Jernigan, S, Yu, X, Wang, L, Callaway, C. W, Gill, G, Chan, G. M, Albertine, K. H, McKnight, R. A, Lane, R. H

“…1 Division of Neonatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 2 David Geffen School of Medicine and…”
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Protease Gene Duplication and Proteolytic Activity in Drosophila Female Reproductive Tracts by Kelleher, Erin S., Pennington, James E.

“…Secreted proteases play integral roles in sexual reproduction in a broad range of taxa. In the genetic model Drosophila melanogaster, these molecules are…”
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