Search Results - "Kelleher, Meredith A"

Creatine Metabolism in Female Reproduction, Pregnancy and Newborn Health by Muccini, Anna Maria, Tran, Nhi T, de Guingand, Deborah L, Philip, Mamatha, Della Gatta, Paul A, Galinsky, Robert, Sherman, Larry S, Kelleher, Meredith A, Palmer, Kirsten R, Berry, Mary J, Walker, David W, Snow, Rod J, Ellery, Stacey J

“…Creatine metabolism is an important component of cellular energy homeostasis. Via the creatine kinase circuit, creatine derived from our diet or synthesized…”
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Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development by Kelleher, Meredith A, Palliser, Hannah K, Walker, David W, Hirst, Jonathan J

“…Progesterone and its neuroactive metabolite, allopregnanolone, are present in high concentrations during pregnancy, but drop significantly following birth…”
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Loss of neurosteroid-mediated protection following stress during fetal life by Hirst, Jonathan J., Cumberland, Angela L., Shaw, Julia C., Bennett, Greer A., Kelleher, Meredith A., Walker, David W., Palliser, Hannah K.

“…•Elevated neurosteroids during pregnancy have major protective and neurotrophic roles in the fetal brain.•Preterm birth and maternal stress during pregnancy…”
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Membrane inflammasome activation by choriodecidual Ureaplasma parvum infection without intra-amniotic infection in a Non-Human Primate model by Tripathy, Sudeshna, Burd, Irina, Kelleher, Meredith A.

“…Intrauterine infection is a significant cause of neonatal morbidity and mortality. Ureaplasma parvum is a microorganism commonly isolated from cases of preterm…”
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Maternal azithromycin therapy for Ureaplasma parvum intraamniotic infection improves fetal hemodynamics in a nonhuman primate model by Kelleher, Meredith A., Lee, Ji Yeon, Roberts, Victoria H.J., Novak, Christopher M., Baschat, Ahmet A., Morgan, Terry K., Novy, Miles J., Räsänen, Juha P., Frias, Antonio E., Burd, Irina

“…Ureaplasma parvum infection is a prevalent cause of intrauterine infection associated with preterm birth, preterm premature rupture of membranes, fetal…”
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Neuroactive steroids in pregnancy: Key regulatory and protective roles in the foetal brain by Hirst, Jonathan J., Kelleher, Meredith A., Walker, David W., Palliser, Hannah K.

“…•Neuroactive steroid concentrations are remarkably high in the foetal life.•Interactions between the placenta and foetal brain regulate allopregnanolone…”
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Changes in neuroactive steroid concentrations after preterm delivery in the Guinea pig by Kelleher, Meredith A, Hirst, Jonathan J, Palliser, Hannah K

“…Preterm birth is a major cause of neurodevelopmental disorders. Allopregnanolone, a key metabolite of progesterone, has neuroprotective and developmental…”
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Beyond the uterine environment: a nonhuman primate model to investigate maternal–fetal and neonatal outcomes following chronic intrauterine infection by Kelleher, Meredith A, Liu, Zheng, Wang, Xiaojie, Kroenke, Christopher D, Houser, Lisa A, Dozier, Brandy L, Martin, Lauren D, Waites, Ken B, McEvoy, Cindy, Schelonka, Robert L, Grigsby, Peta L

“…Background Intrauterine infection is a significant cause of early preterm birth. We have developed a fetal–neonatal model in the rhesus macaque to determine…”
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The guinea pig as an animal model for studying perinatal changes in microvascular function by Dyson, Rebecca M., Palliser, Hannah K., Kelleher, Meredith A., Hirst, Jonathan J., Wright, Ian M.R.

“…Introduction: Microvascular dysfunction, characterized by inappropriate vasodilatation and high blood flow in the peripheral microcirculation, is linked to…”
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Mechanisms leading to increased risk of preterm birth in growth-restricted guinea pig pregnancies by Palliser, Hannah K, Kelleher, Meredith A, Welsh, Toni N, Zakar, Tamas, Hirst, Jonathan J

“…Intrauterine growth restriction (IUGR) is a risk factor for preterm labor; however, the mechanisms of the relationship remain unknown. Prostaglandin (PG), key…”
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