Search Results - "Kelleher, Anthony"

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection by Phetsouphanh, Chansavath, Darley, David R., Wilson, Daniel B., Howe, Annett, Munier, C. Mee Ling, Patel, Sheila K., Juno, Jennifer A., Burrell, Louise M., Kent, Stephen J., Dore, Gregory J., Kelleher, Anthony D., Matthews, Gail V.

“…A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than…”
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Pacific Eclipse: Before the corona dawn by Kelleher, Anthony D.

“…The scenario based interactive meeting attracted academics including epidemiologists, infectious disease experts, immunologists, vaccinologists, public health…”
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T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses by Suan, Dan, Nguyen, Akira, Moran, Imogen, Bourne, Katherine, Hermes, Jana R., Arshi, Mehreen, Hampton, Henry R., Tomura, Michio, Miwa, Yoshihiro, Kelleher, Anthony D., Kaplan, Warren, Deenick, Elissa K., Tangye, Stuart G., Brink, Robert, Chtanova, Tatyana, Phan, Tri Giang

“…B helper follicular T (Tfh) cells are critical for long-term humoral immunity. However, it remains unclear how these cells are recruited and contribute to…”
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SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants by Tea, Fiona, Ospina Stella, Alberto, Aggarwal, Anupriya, Ross Darley, David, Pilli, Deepti, Vitale, Daniele, Merheb, Vera, Lee, Fiona X. Z, Cunningham, Philip, Walker, Gregory J, Fichter, Christina, Brown, David A, Rawlinson, William D, Isaacs, Sonia R, Mathivanan, Vennila, Hoffmann, Markus, Pöhlman, Stefan, Mazigi, Ohan, Christ, Daniel, Dwyer, Dominic E, Rockett, Rebecca J, Sintchenko, Vitali, Hoad, Veronica C, Irving, David O, Dore, Gregory J, Gosbell, Iain B, Kelleher, Anthony D, Matthews, Gail V, Brilot, Fabienne, Turville, Stuart G

“…The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody neutralization response and its evasion by emerging viral variants and variant of…”
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Immune activation and immune aging in HIV infection by Appay, Victor, Kelleher, Anthony D

“…PURPOSE OF REVIEWThe development of serious non-AIDS-related pathologies typically associated with aging, and the premature immune aging that characterizes…”
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Functional cure of HIV: the scale of the challenge by Davenport, Miles P., Khoury, David S., Cromer, Deborah, Lewin, Sharon R., Kelleher, Anthony D., Kent, Stephen J.

“…A variety of interventions to induce a functional cure of HIV are being explored, with the aim being to allow patients to cease antiretroviral therapy (ART)…”
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Advances in HIV Gene Therapy by Kitawi, Rose, Ledger, Scott, Kelleher, Anthony D, Ahlenstiel, Chantelle L

“…Early gene therapy studies held great promise for the cure of heritable diseases, but the occurrence of various genotoxic events led to a pause in clinical…”
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Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody by Singh, Mandeep, Jackson, Katherine J.L., Wang, Jing J., Schofield, Peter, Field, Matt A., Koppstein, David, Peters, Timothy J., Burnett, Deborah L., Rizzetto, Simone, Nevoltris, Damien, Masle-Farquhar, Etienne, Faulks, Megan L., Russell, Amanda, Gokal, Divya, Hanioka, Asami, Horikawa, Keisuke, Colella, Alexander D., Chataway, Timothy K., Blackburn, James, Mercer, Tim R., Langley, David B., Goodall, D. Margaret, Jefferis, Roy, Gangadharan Komala, Muralikrishna, Kelleher, Anthony D., Suan, Dan, Rischmueller, Maureen, Christ, Daniel, Brink, Robert, Luciani, Fabio, Gordon, Tom P., Goodnow, Christopher C., Reed, Joanne H.

“…Pathogenic autoantibodies arise in many autoimmune diseases, but it is not understood how the cells making them evade immune checkpoints. Here, single-cell…”
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Molecular epidemiology to aid virtual elimination of HIV transmission in Australia by Obeng, Billal M., Kelleher, Anthony D., Di Giallonardo, Francesca

“…•Australia can achieve virtual elimination of HIV through molecular epidemiology.•Major drivers of HIV transmission are early infection and the…”
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The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells by Duette, Gabriel, Hiener, Bonnie, Morgan, Hannah, Mazur, Fernando G, Mathivanan, Vennila, Horsburgh, Bethany A, Fisher, Katie, Tong, Orion, Lee, Eunok, Ahn, Haelee, Shaik, Ansari, Fromentin, Rémi, Hoh, Rebecca, Bacchus-Souffan, Charline, Nasr, Najla, Cunningham, Anthony L, Hunt, Peter W, Chomont, Nicolas, Turville, Stuart G, Deeks, Steven G, Kelleher, Anthony D, Schlub, Timothy E, Palmer, Sarah

“…Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4+ T cells that contribute to viral rebound if treatment is interrupted…”
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HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission by Pinkevych, Mykola, Cromer, Deborah, Tolstrup, Martin, Grimm, Andrew J, Cooper, David A, Lewin, Sharon R, Søgaard, Ole S, Rasmussen, Thomas A, Kent, Stephen J, Kelleher, Anthony D, Davenport, Miles P

“…HIV infection can be effectively controlled by anti-retroviral therapy (ART) in most patients. However therapy must be continued for life, because interruption…”
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Cytotoxic CD4 T Cells-Friend or Foe during Viral Infection? by Juno, Jennifer A, van Bockel, David, Kent, Stephen J, Kelleher, Anthony D, Zaunders, John J, Munier, C Mee Ling

“…CD4 T cells with cytotoxic function were once thought to be an artifact due to long-term cultures but have in more recent years become accepted and reported in…”
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Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract by Zhang, Yuan, Almazi, Juhura G, Ong, Hui Xin, Johansen, Matt D, Ledger, Scott, Traini, Daniela, Hansbro, Philip M, Kelleher, Anthony D, Ahlenstiel, Chantelle L

“…Since December 2019, a pandemic of COVID-19 disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the…”
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RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency by Méndez, Catalina, Ledger, Scott, Petoumenos, Kathy, Ahlenstiel, Chantelle, Kelleher, Anthony D

“…Current antiretroviral therapy is effective in controlling HIV-1 infection. However, cessation of therapy is associated with rapid return of viremia from the…”
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Block and Lock HIV Cure Strategies to Control the Latent Reservoir by Ahlenstiel, Chantelle L, Symonds, Geoff, Kent, Stephen J, Kelleher, Anthony D

“…The HIV latent reservoir represents the major challenge to cure development. Residing in resting CD4+ T cells and myeloid cells at multiple locations in the…”
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Global burden of transmitted HIV drug resistance and HIV-exposure categories: a systematic review and meta-analysis by PHAM, Quang D, WILSON, David P, LAW, Matthew G, KELLEHER, Anthony D, LEI ZHANG

“…Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and…”
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Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia by Dharan, Nila J, Sasson, Sarah C, Ahlenstiel, Golo, Andersen, Christopher R, Bloch, Mark, Buckland, Griselda, Hamad, Nada, Han, Win Min, Kelleher, Anthony D, Long, Georgina V, Matthews, Gail V, Mina, Michael M, Papot, Emmanuelle, Petoumenos, Kathy, Swaminathan, Sanjay, Withers, Barbara, Yun, James, Polizzotto, Mark N

“…People with immunocompromising conditions are at increased risk of SARS-CoV-2 infection and mortality, however early in the pandemic it was challenging to…”
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Evaluation of Commercially Available Viral Transport Medium (VTM) for SARS-CoV-2 Inactivation and Use in Point-of-Care (POC) Testing by van Bockel, David, Munier, C Mee Ling, Turville, Stuart, Badman, Steven G, Walker, Gregory, Stella, Alberto Ospina, Aggarwal, Anupriya, Yeang, Malinna, Condylios, Anna, Kelleher, Anthony D, Applegate, Tanya L, Vallely, Andrew, Whiley, David, Rawlinson, William, Cunningham, Phillip, Kaldor, John, Guy, Rebecca

“…Critical to facilitating SARS-CoV-2 point-of-care (POC) testing is assurance that viruses present in specimens are inactivated onsite prior to processing…”
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Immunological biomarkers predict HIV-1 viral rebound after treatment interruption by Hurst, Jacob, Hoffmann, Matthias, Pace, Matthew, Williams, James P., Thornhill, John, Hamlyn, Elizabeth, Meyerowitz, Jodi, Willberg, Chris, Koelsch, Kersten K., Robinson, Nicola, Brown, Helen, Fisher, Martin, Kinloch, Sabine, Cooper, David A., Schechter, Mauro, Tambussi, Giuseppe, Fidler, Sarah, Babiker, Abdel, Weber, Jonathan, Kelleher, Anthony D., Phillips, Rodney E., Frater, John

“…Treatment of HIV-1 infection with antiretroviral therapy (ART) in the weeks following transmission may induce a state of ‘post-treatment control’ (PTC) in some…”
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Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes by Moran, Imogen, Nguyen, Akira, Khoo, Weng Hua, Butt, Danyal, Bourne, Katherine, Young, Clara, Hermes, Jana R., Biro, Maté, Gracie, Gary, Ma, Cindy S., Munier, C. Mee Ling, Luciani, Fabio, Zaunders, John, Parker, Andrew, Kelleher, Anthony D., Tangye, Stuart G., Croucher, Peter I., Brink, Robert, Read, Mark N., Phan, Tri Giang

“…Vaccine-induced immunity depends on the generation of memory B cells (MBC). However, where and how MBCs are reactivated to make neutralising antibodies remain…”
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