Search Results - "Kellar, Robert S"

Arsenic Impairs Wound Healing Processes in Dermal Fibroblasts and Mice by Dresler, Sara R, Pinto, Bronson I, Salanga, Matthew C, Propper, Catherine R, Berry, Savannah R, Kellar, Robert S

“…Inorganic arsenic (NaAsO ) is a naturally occurring metalloid found in water resources globally and in the United States at concentrations exceeding the U.S…”
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In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration by Pinto, Bronson I, Cruz, Nathan D, Lujan, Oscar R, Propper, Catherine R, Kellar, Robert S

“…Understanding the physiologic mechanisms of wound healing has been the focus of ongoing research for many years. This research directly translates into changes…”
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An electrically coupled tissue-engineered cardiomyocyte scaffold improves cardiac function in rats with chronic heart failure by Lancaster, Jordan J., MS, Juneman, Elizabeth, MD, Arnce, Sarah A., MMS, PA-C, Johnson, Nicholle M., BS, Qin, Yexian, PhD, Witte, Russell, PhD, Thai, Hoang, MD, Kellar, Robert S., PhD, Ek Vitorin, Jose, PhD, MD, Burt, Janis, PhD, Gaballa, Mohamed A., PhD, Bahl, Joseph J., PhD, Goldman, Steven, MD

“…Background Varying strategies are currently being evaluated to develop tissue-engineered constructs for the treatment of ischemic heart disease. This study…”
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TGFβ2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs by Ardila, Diana C, Tamimi, Ehab, Danford, Forest L, Haskett, Darren G, Kellar, Robert S, Doetschman, Tom, Vande Geest, Jonathan P

“…Abstract A main goal of tissue engineering is the development of scaffolds that replace, restore and improve injured tissue. These scaffolds have to mimic…”
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Sex Differences in Antioxidant Gene Expression in response to Chronic Arsenic Exposure by Berry, Savannah R., Dresler, Sara R., Propper, Catherine R., Kellar, Robert S., Traustadóttir, Tinna

“…Inorganic arsenic is highly toxic metalloid considered a water contaminant that is naturally occurring through geological formations where it leaches into…”
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An acellular tissue engineered biomimetic wound healing device created using collagen and tropoelastin accelerates wound healing by Diller, Robert B., Kellar, Robert S.

“…Tissue engineering has historically involved research combining scaffolds, cells, and active biomolecules to treat multiple pathologies. The current research…”
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Integration of choline geranate into electrospun protein scaffolds affords antimicrobial activity to biomaterials used for cutaneous wound healing by Bardsley, Tatum A., Evans, Charlotte L., Greene, Joshua R., Audet, Robert, Harrison, Mackenzie J., Zimmerman, Maxwell, Nieto, Nathan C., Del Sesto, Rico E., Koppisch, Andrew T., Kellar, Robert S.

“…Wound healing attempts to maintain homeostasis in the wound while minimizing the risk of infection to the tissue by foreign agents, such as opportunistic…”
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TGF beta 2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs by Ardila, Diana C, Tamimi, Ehab, Danford, est L, Haskett, Darren G, Kellar, Robert S, Doetschman, Tom, Vande Geest, Jonathan P

“…A main goal of tissue engineering is the development of scaffolds that replace, restore and improve injured tissue. These scaffolds have to mimic natural…”
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Pilot study: Autologous platelet‐rich plasma used in a topical cream for facial rejuvenation by Draelos, Zoe Diana, Rheins, Lawrence A., Wootten, Shaun, Kellar, Robert S., Diller, Robert B.

“…Background Platelet rich plasma (PRP) is traditionally used as an injectable material for enhanced healing, hair growth, and facial rejuvenation. Aims This…”
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Cardiac patch constructed from human fibroblasts attenuates reduction in cardiac function after acute infarct by Kellar, Robert S, Shepherd, Benjamin R, Larson, Doug F, Naughton, Gail K, Williams, Stuart K

“…The current experiments used a scaffold-based, three-dimensional, human dermal fibroblast culture (3DFC) as a cardiac patch to stimulate revascularization and…”
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Validating whole slide digital morphometric analysis as a microscopy tool by Diller, Robert B, Kellar, Robert S

“…Whole slide imaging (WSI) can be used to quantify multiple responses within tissue sections during histological analysis. Feature Analysis on Consecutive…”
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Topically delivered dissolved oxygen reduces inflammation and positively influences structural proteins in healthy intact human skin by Kellar, Robert S, Audet, Robert G, Roe, David F, Rheins, Lawrence A, Draelos, Zoe Diana

“…Summary Background As oxygen is essential for wound healing and there is limited diffusion across the stratum corneum into the epidermis, we wanted to evaluate…”
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Scaffold-based three-dimensional human fibroblast culture provides a structural matrix that supports angiogenesis in infarcted heart tissue by KELLAR, Robert S, LANDEEN, Lee K, SHEPHERD, Benjamin R, NAUGHTON, Gail K, RATCLIFFE, Anthony, WILLIAMS, Stuart K

“…We have developed techniques to implant angiogenic patches onto the epicardium over regions of infarcted cardiac tissue to stimulate revascularization of the…”
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Antibody to Granulocyte Macrophage Colony–stimulating Factor Reduces the Number of Activated Tissue Macrophages and Improves Left Ventricular Function After Myocardial Infarction in a Rat Coronary Artery Ligation Model by Kellar, Robert S, Lancaster, Jordan J, Thai, Hoang M, Juneman, Elizabeth, Johnson, Nicholle M, Byrne, Howard G, Stansifer, Maribeth, Arsanjani, Reza, Baer, Mark, Bebbington, Christopher, Flashner, Michael, Yarranton, Geoffrey, Goldman, Steven

“…Granulocyte macrophage colony-stimulating factor (GM-CSF) promotes infarct expansion and inappropriate collagen synthesis in a myocardial infarction (MI). This…”
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Three-dimensional fibroblast cultures stimulate improved ventricular performance in chronically ischemic canine hearts by Kellar, Robert S, Williams, Stuart K, Naughton, Gail K, Figliozzi, Gianine M, Siani-Rose, Michael

“…The current study's purpose was to evaluate the safety and biological effect of a scaffold-based three-dimensional human dermal fibroblast culture (3DFC, also…”
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Hypoxic conditioned culture medium from fibroblasts grown under embryonic-like conditions supports healing following post-laser resurfacing by Kellar, Robert S, Hubka, Mark, Rheins, Lawrence A, Fisher, Garth, Naughton, Gail K

“…Summary Objectives  Treatment of facial skin perturbed by laser resurfacing with a novel, topical hypoxic conditioned culture medium (HCCM) product results in…”
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In Vivo Evaluation of a Biologically Active Cardiomyocyte Seeded Scaffold by Lancaster, Jordan J, Arnce, Sarah A, Johnson, Nicholle M, Juneman, Elizabeth, Thai, Hoang, Kellar, Robert S, Vitorin, Jose Ek, Burt, Janis, Bahl, Joseph J, Goldman, Steven

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Treatment of Acute Myocardial Infarction Versus Heart Failure with a Viable 3-Dimensional Fibroblast Patch by Lancaster, Jordan J, Kellar, Robert S, Thai, Hoang M, Juneman, Elizabeth B, Johnson, Nicholle M, Byrne, Howard G, Stansifer, Maribeth, Goldman, Steven

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Granulocyte-Macrophage Colony-Stimulating Factor Antibody Improves Left Ventricular Function and Limits Maladaptive Remodeling Following Myocardial Infarction by Lancaster, Jordan J, Kellar, Robert S, Thai, Hoang M, Juneman, Elizabeth B, Johnson, Nicholle M, Byrne, Howard G, Stansifer, Maribeth, Bebbington, Christopher, Yarranton, Geoffrey, Goldman, Steven

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Characterization of angiogenesis and inflammation surrounding ePTFE implanted on the epicardium by Kellar, Robert S., Kleinert, Leigh B., Williams, Stuart K.

“…The response of epicardial tissue to the implantation of expanded polytetrafluoroethylene (ePTFE) was evaluated and compared with identical material implanted…”
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