Search Results - "Kellar, Robert"
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Sex Differences in Antioxidant Gene Expression in response to Chronic Arsenic Exposure
Published in The FASEB journal (01-05-2022)“…Inorganic arsenic is highly toxic metalloid considered a water contaminant that is naturally occurring through geological formations where it leaches into…”
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An acellular tissue engineered biomimetic wound healing device created using collagen and tropoelastin accelerates wound healing
Published in Journal of tissue viability (01-08-2022)“…Tissue engineering has historically involved research combining scaffolds, cells, and active biomolecules to treat multiple pathologies. The current research…”
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Arsenic Impairs Wound Healing Processes in Dermal Fibroblasts and Mice
Published in International journal of molecular sciences (01-02-2024)“…Inorganic arsenic (NaAsO ) is a naturally occurring metalloid found in water resources globally and in the United States at concentrations exceeding the U.S…”
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In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration
Published in Journal of visualized experiments (23-02-2019)“…Understanding the physiologic mechanisms of wound healing has been the focus of ongoing research for many years. This research directly translates into changes…”
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Integration of choline geranate into electrospun protein scaffolds affords antimicrobial activity to biomaterials used for cutaneous wound healing
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-09-2021)“…Wound healing attempts to maintain homeostasis in the wound while minimizing the risk of infection to the tissue by foreign agents, such as opportunistic…”
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Environmentally Relevant Levels of Depleted Uranium Impacts Dermal Fibroblast Proliferation, Viability, Metabolic Activity, and Scratch Closure
Published in Toxics (Basel) (03-09-2021)“…Uranium (U) is a heavy metal used in military and industrial settings, with a large portion being mined from the Southwest region of the United States. Uranium…”
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TGF beta 2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs
Published in Biomaterials (01-01-2015)“…A main goal of tissue engineering is the development of scaffolds that replace, restore and improve injured tissue. These scaffolds have to mimic natural…”
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Pilot study: Autologous platelet‐rich plasma used in a topical cream for facial rejuvenation
Published in Journal of cosmetic dermatology (01-10-2019)“…Background Platelet rich plasma (PRP) is traditionally used as an injectable material for enhanced healing, hair growth, and facial rejuvenation. Aims This…”
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An electrically coupled tissue-engineered cardiomyocyte scaffold improves cardiac function in rats with chronic heart failure
Published in The Journal of heart and lung transplantation (01-04-2014)“…Background Varying strategies are currently being evaluated to develop tissue-engineered constructs for the treatment of ischemic heart disease. This study…”
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10
Validating whole slide digital morphometric analysis as a microscopy tool
Published in Microscopy and microanalysis (01-02-2015)“…Whole slide imaging (WSI) can be used to quantify multiple responses within tissue sections during histological analysis. Feature Analysis on Consecutive…”
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TGFβ2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs
Published in Biomaterials (01-01-2015)“…Abstract A main goal of tissue engineering is the development of scaffolds that replace, restore and improve injured tissue. These scaffolds have to mimic…”
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Clinical and Histologic Assessment of Lateral Alveolar Ridge Augmentation Using a Synthetic Long‐Term Bioabsorbable Membrane and an Allograft
Published in Journal of periodontology (1970) (01-07-2008)“…Background: Guided bone regeneration (GBR) is a widely used procedure for augmenting alveolar ridge width prior to placement of endosseous implants. Various…”
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Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction
Published in Cell transplantation (01-01-2009)“…This study was designed to determine if a viable biodegradable three-dimensional fibroblast construct (3DFC) patch implanted on the left ventricle after…”
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Topically delivered dissolved oxygen reduces inflammation and positively influences structural proteins in healthy intact human skin
Published in Journal of cosmetic dermatology (01-06-2013)“…Summary Background As oxygen is essential for wound healing and there is limited diffusion across the stratum corneum into the epidermis, we wanted to evaluate…”
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Scaffold-based three-dimensional human fibroblast culture provides a structural matrix that supports angiogenesis in infarcted heart tissue
Published in Circulation (New York, N.Y.) (23-10-2001)“…We have developed techniques to implant angiogenic patches onto the epicardium over regions of infarcted cardiac tissue to stimulate revascularization of the…”
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Antibody to Granulocyte Macrophage Colony–stimulating Factor Reduces the Number of Activated Tissue Macrophages and Improves Left Ventricular Function After Myocardial Infarction in a Rat Coronary Artery Ligation Model
Published in Journal of cardiovascular pharmacology (01-05-2011)“…Granulocyte macrophage colony-stimulating factor (GM-CSF) promotes infarct expansion and inappropriate collagen synthesis in a myocardial infarction (MI). This…”
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Three-dimensional fibroblast cultures stimulate improved ventricular performance in chronically ischemic canine hearts
Published in Tissue engineering. Part A (01-09-2011)“…The current study's purpose was to evaluate the safety and biological effect of a scaffold-based three-dimensional human dermal fibroblast culture (3DFC, also…”
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Hypoxic conditioned culture medium from fibroblasts grown under embryonic-like conditions supports healing following post-laser resurfacing
Published in Journal of cosmetic dermatology (01-09-2009)“…Summary Objectives Treatment of facial skin perturbed by laser resurfacing with a novel, topical hypoxic conditioned culture medium (HCCM) product results in…”
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HUMAN ALLOGRAFTS IMPROVE HEALING OUTCOMES IN CHRONIC WOUNDS
Published in The FASEB journal (01-04-2020)“…Abstract only Background Chronic wounds affect an estimated 8 million people worldwide and are often a result of underlying health conditions, such as obesity,…”
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In Vivo Evaluation of a Biologically Active Cardiomyocyte Seeded Scaffold
Published in Journal of cardiac failure (2010)Get full text
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