Search Results - "Kellam, Paul"

The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection by Kellam, Paul, Barclay, Wendy

“…SARS-CoV-2 is a novel coronavirus that is the causative agent of coronavirus infectious disease 2019 (COVID-19). As of 17 April 2020, it has infected 2 114 269…”
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Antibody response to SARS-CoV-2 infection in humans: A systematic review by Post, Nathan, Eddy, Danielle, Huntley, Catherine, van Schalkwyk, May C I, Shrotri, Madhumita, Leeman, David, Rigby, Samuel, Williams, Sarah V, Bermingham, William H, Kellam, Paul, Maher, John, Shields, Adrian M, Amirthalingam, Gayatri, Peacock, Sharon J, Ismail, Sharif A

“…Progress in characterising the humoral immune response to Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist…”
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Scientific consensus on the COVID-19 pandemic: we need to act now by Alwan, Nisreen A, Burgess, Rochelle Ann, Ashworth, Simon, Beale, Rupert, Bhadelia, Nahid, Bogaert, Debby, Dowd, Jennifer, Eckerle, Isabella, Goldman, Lynn R, Greenhalgh, Trisha, Gurdasani, Deepti, Hamdy, Adam, Hanage, William P, Hodcroft, Emma B, Hyde, Zoë, Kellam, Paul, Kelly-Irving, Michelle, Krammer, Florian, Lipsitch, Marc, McNally, Alan, McKee, Martin, Nouri, Ali, Pimenta, Dominic, Priesemann, Viola, Rutter, Harry, Silver, Joshua, Sridhar, Devi, Swanton, Charles, Walensky, Rochelle P, Yamey, Gavin, Ziauddeen, Hisham

“…The infection fatality rate of COVID-19 is several-fold higher than that of seasonal influenza,2 and infection can lead to persisting illness, including in…”
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T cell response to SARS-CoV-2 infection in humans: A systematic review by Shrotri, Madhumita, van Schalkwyk, May C I, Post, Nathan, Eddy, Danielle, Huntley, Catherine, Leeman, David, Rigby, Samuel, Williams, Sarah V, Bermingham, William H, Kellam, Paul, Maher, John, Shields, Adrian M, Amirthalingam, Gayatri, Peacock, Sharon J, Ismail, Sharif A

“…Understanding the T cell response to SARS-CoV-2 is critical to vaccine development, epidemiological surveillance and disease control strategies. This…”
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Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus by Assiri, Abdullah, McGeer, Allison, Perl, Trish M, Price, Connie S, Al Rabeeah, Abdullah A, Cummings, Derek A.T, Alabdullatif, Zaki N, Assad, Maher, Almulhim, Abdulmohsen, Makhdoom, Hatem, Madani, Hossam, Alhakeem, Rafat, Al-Tawfiq, Jaffar A, Cotten, Matthew, Watson, Simon J, Kellam, Paul, Zumla, Alimuddin I, Memish, Ziad A

“…A novel coronavirus (MERS-CoV) is causing severe disease in the Middle East. In this report on a hospital outbreak of MERS-CoV infection, 23 confirmed cases…”
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IVA: accurate de novo assembly of RNA virus genomes by Hunt, Martin, Gall, Astrid, Ong, Swee Hoe, Brener, Jacqui, Ferns, Bridget, Goulder, Philip, Nastouli, Eleni, Keane, Jacqueline A, Kellam, Paul, Otto, Thomas D

“…An accurate genome assembly from short read sequencing data is critical for downstream analysis, for example allowing investigation of variants within a…”
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Host genetics of Epstein-Barr virus infection, latency and disease by Houldcroft, Charlotte J., Kellam, Paul

“…Summary Epstein–Barr virus (EBV) infects 95% of the adult population and is the cause of infectious mononucleosis. It is also associated with 1% of cancers…”
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Widespread Reassortment Shapes the Evolution and Epidemiology of Bluetongue Virus following European Invasion by Nomikou, Kyriaki, Hughes, Joseph, Wash, Rachael, Kellam, Paul, Breard, Emmanuel, Zientara, Stéphan, Palmarini, Massimo, Biek, Roman, Mertens, Peter

“…Genetic exchange by a process of genome-segment 'reassortment' represents an important mechanism for evolutionary change in all viruses with segmented genomes,…”
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Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction by Foster, Toshana L., Wilson, Harry, Iyer, Shilpa S., Coss, Karen, Doores, Katie, Smith, Sarah, Kellam, Paul, Finzi, Andrés, Borrow, Persephone, Hahn, Beatrice H., Neil, Stuart J.D.

“…Interferon-induced transmembrane proteins (IFITMs) restrict the entry of diverse enveloped viruses through incompletely understood mechanisms. While IFITMs are…”
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Human Coronavirus NL63 Molecular Epidemiology and Evolutionary Patterns in Rural Coastal Kenya by Kiyuka, Patience K, Agoti, Charles N, Munywoki, Patrick K, Njeru, Regina, Bett, Anne, Otieno, James R, Otieno, Grieven P, Kamau, Everlyn, Clark, Taane G, van der Hoek, Lia, Kellam, Paul, Nokes, D James, Cotten, Matthew

“…Abstract Background Human coronavirus NL63 (HCoV-NL63) is a globally endemic pathogen causing mild and severe respiratory tract infections with reinfections…”
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Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases by Correia, Samantha, Bridges, Ray, Wegner, Fanny, Venturini, Cristina, Palser, Anne, Middeldorp, Jaap M, Cohen, Jeffrey I, Lorenzetti, Mario A, Bassano, Irene, White, Robert E, Kellam, Paul, Breuer, Judith, Farrell, Paul J

“…One hundred thirty-eight new Epstein-Barr virus (EBV) genome sequences have been determined. One hundred twenty-five of these and 116 from previous reports…”
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Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013 by Memish, Ziad A, Cotten, Matthew, Meyer, Benjamin, Watson, Simon J, Alsahafi, Abdullah J, Al Rabeeah, Abdullah A, Corman, Victor Max, Sieberg, Andrea, Makhdoom, Hatem Q, Assiri, Abdullah, Al Masri, Malaki, Aldabbagh, Souhaib, Bosch, Berend-Jan, Beer, Martin, Müller, Marcel A, Kellam, Paul, Drosten, Christian

“…We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole…”
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Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection by Palser, Anne L, Grayson, Nicholas E, White, Robert E, Corton, Craig, Correia, Samantha, Ba Abdullah, Mohammed M, Watson, Simon J, Cotten, Matthew, Arrand, John R, Murray, Paul G, Allday, Martin J, Rickinson, Alan B, Young, Lawrence S, Farrell, Paul J, Kellam, Paul

“…Epstein-Barr virus (EBV) infects most of the world's population and is causally associated with several human cancers, but little is known about how EBV…”
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Viral population analysis and minority-variant detection using short read next-generation sequencing by Watson, Simon J., Welkers, Matthijs R. A., Depledge, Daniel P., Coulter, Eve, Breuer, Judith M., de Jong, Menno D., Kellam, Paul

“…RNA viruses within infected individuals exist as a population of evolutionary-related variants. Owing to evolutionary change affecting the constitution of this…”
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Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013 by Watson, Simon J, Langat, Pinky, Reid, Scott M, Lam, Tommy Tsan-Yuk, Cotten, Matthew, Kelly, Michael, Van Reeth, Kristien, Qiu, Yu, Simon, Gaëlle, Bonin, Emilie, Foni, Emanuela, Chiapponi, Chiara, Larsen, Lars, Hjulsager, Charlotte, Markowska-Daniel, Iwona, Urbaniak, Kinga, Dürrwald, Ralf, Schlegel, Michael, Huovilainen, Anita, Davidson, Irit, Dán, Ádám, Loeffen, Willie, Edwards, Stephanie, Bublot, Michel, Vila, Thais, Maldonado, Jaime, Valls, Laura, Brown, Ian H, Pybus, Oliver G, Kellam, Paul

“…The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus of swine origin, highlighted the importance of worldwide influenza…”
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Genome-wide evolutionary dynamics of influenza B viruses on a global scale by Langat, Pinky, Raghwani, Jayna, Dudas, Gytis, Bowden, Thomas A, Edwards, Stephanie, Gall, Astrid, Bedford, Trevor, Rambaut, Andrew, Daniels, Rodney S, Russell, Colin A, Pybus, Oliver G, McCauley, John, Kellam, Paul, Watson, Simon J

“…The global-scale epidemiology and genome-wide evolutionary dynamics of influenza B remain poorly understood compared with influenza A viruses. We compiled a…”
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Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA by Correia, Samantha, Palser, Anne, Elgueta Karstegl, Claudio, Middeldorp, Jaap M, Ramayanti, Octavia, Cohen, Jeffrey I, Hildesheim, Allan, Fellner, Maria Dolores, Wiels, Joelle, White, Robert E, Kellam, Paul, Farrell, Paul J

“…Viral gene sequences from an enlarged set of about 200 Epstein-Barr virus (EBV) strains, including many primary isolates, have been used to investigate…”
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Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study by Cotten, Matthew, PhD, Watson, Simon J, PhD, Kellam, Paul, Prof, Al-Rabeeah, Abdullah A, FRCS, Makhdoom, Hatem Q, PhD, Assiri, Abdullah, MD, Al-Tawfiq, Jaffar A, MD, Alhakeem, Rafat F, MD, Madani, Hossam, PhD, AlRabiah, Fahad A, MD, Hajjar, Sami Al, MD, Al-nassir, Wafa N, MD, Albarrak, Ali, MD, Flemban, Hesham, MD, Balkhy, Hanan H, MD, Alsubaie, Sarah, MD, Palser, Anne L, PhD, Gall, Astrid, Dr Med Vet, Bashford-Rogers, Rachael, MChem, Rambaut, Andrew, Prof, Zumla, Alimuddin I, Prof, Memish, Ziad A, Prof

“…Summary Background Since June, 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) has, worldwide, caused 104 infections in people including 49…”
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Universal Amplification, Next-Generation Sequencing, and Assembly of HIV-1 Genomes by GALL, Astrid, FERNS, Bridget, MORRIS, Clare, WATSON, Simon, COTTEN, Matthew, ROBINSON, Mark, BERRY, Neil, PILLAY, Deenan, KELLAM, Paul

“…OA  Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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A membrane topology model for human interferon inducible transmembrane protein 1 by Weston, Stuart, Czieso, Stephanie, White, Ian J, Smith, Sarah E, Kellam, Paul, Marsh, Mark

“…InterFeron Inducible TransMembrane proteins 1-3 (IFITM1, IFITM2 and IFITM3) are a family of proteins capable of inhibiting the cellular entry of numerous human…”
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