Search Results - "Kelicen, Pelin"

Effect of atorvastatin on Aβ1–42‐induced alteration of SESN2, SIRT1, LC3II and TPP1 protein expressions in neuronal cell cultures by Çelik, Hande, Karahan, Hande, Kelicen‐Uğur, Pelin

“…Objectives Sestrins (SESNs) and sirtuins (SIRTs) are antioxidant and antiapoptotic genes and crucial mediators for lysosomal autophagy regulation that play a…”
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Titanium‐Based Nanoarchitectures for Sonodynamic Therapy‐Involved Multimodal Treatments by Maleki, Aziz, Seyedhamzeh, Mohammad, Yuan, Meng, Agarwal, Tarun, Sharifi, Ibrahim, Mohammadi, Abbas, Kelicen‐Uğur, Pelin, Hamidi, Mehrdad, Malaki, Massoud, Al Kheraif, Abdulaziz A., Cheng, Ziyong, Lin, Jun

“…Sonodynamic therapy (SDT) has considerably revolutionized the healthcare sector as a viable noninvasive therapeutic procedure. It employs a combination of…”
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Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Cells via Decreased Oxidative Damage and Increased Phagocytosis by Elmazoglu, Zubeyir, Kayhan, Handan, Santamaría, Abel, Rangel-López, Edgar, Uğur, Pelin Kelicen, Ceylan, Aslı, Aschner, Michael, Karasu, Çimen

“…Neuroinflammation and oxidative stress cooperate to compromise the function of the central nervous system (CNS). Colloidal platinum nanoparticles (Pt NPs) are…”
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Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid-induced experimental model of acute seizures in rats by Cincioğlu-Palabiyik, Mehtap, Üner, Meral, Ertoy-Baydar, Dilek, Sara, Yildirim, Karahan, Hande, Kelicen-Uğur, Pelin

“…Reproductive disorders are more common in men with epilepsy taking anticonvulsant medications. Antiseizure/anticonvulsant drugs and seizures in medial temporal…”
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Tackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectives by Yaşayan, Gökçen, Nejati, Omid, Ceylan, Asli F., Karasu, Çimen, Kelicen Ugur, Pelin, Bal-Öztürk, Ayça, Zarepour, Atefeh, Zarrabi, Ali, Mostafavi, Ebrahim

“…•The chronic wounds and intracellular pathways involved in this process are elaborated.•Advantages and mechanisms of nanoparticles for wound healing are…”
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Evaluation of the Relationship between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells by Kartal, Yasemin, Tokat, Unal Metin, Kelicen-Ugur, Pelin, Yılmaz, Serkan, Karahan, Sevilay, Budak, Murat Timur

“…Changes in activation/inhibition of Sirtuin-1 (SIRT1) and aromatase play an important role in a plethora of diseases. MicroRNAs (miRNAs) modulate multiple…”
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Synthesis and anti-inflammatory activity of 1-acylthiosemicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones by Palaska, Erhan, Şahin, Gülay, Kelicen, Pelin, Durlu, N.Tuğba, Altinok, Gülçin

“…Sixteen 1-(2-naphthyloxyacetyl)-4-substituted-3-thiosemicarbazide, 2-(2-naphthyloxymethyl)-5-substitutedamino-1,3,4-oxadiazole,…”
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Megestrol acetate inhibits the expression of cytoplasmic aromatase through nuclear C/EBPβ in reperfusion injury-induced ischemic rat hippocampus by Kelicen Ugur, Pelin, Lule, Sevda, Cincioglu, Mehtap, Pekiner, Can, Gursoy-Ozdemir, Yasemin

“…Global ischemia after cardiac arrest, intraoperative hypoxia/hypotension, and hemorrhagic shock causes brain injury resulting in severe neurological and…”
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Synthesis and anti-inflammatory activities of some thiazolo[3,2-a]pyrimidine derivatives by Tozkoparan, Birsen, Ertan, Mevlüt, Kelicen, Pelin, Demirdamar, Rümeysa

“…Sixteen new 2-benzylidene-7-methyl-3-oxo-5-(substituted phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl esters ( 1a– 4d) have been…”
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Neuroactivity of the naturally occurring aporphine alkaloid, roemerine by Bayazeid, Omer, Nemutlu, Emirhan, Eylem, Cemil Can, İlhan, Mert, Küpeli-Akkol, Esra, Karahan, Hande, Kelicen-Uğur, Pelin, Ersoz, Tayfun, Yalçın, Funda N

“…Roemerine is a naturally occurring aporphine alkaloid. In this study, we screened a conformer library of Food and Drug Administration (FDA)-approved drugs to…”
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Effect of Three PDEIs on Neuroprotective and Autophagy Proteins in vitro AD Model by Saygisever, Kubra, Faikoglu, Gokhan, Celik, Hande, Ugur, Sedat Askin, Gokhan Akk, Ahmet, Kelicen-Ug, Pelin, Ozyazgan, Sibel

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Interactions of aromatase and seladin-1: A neurosteroidogenic and gender perspective by Kelicen-Ugur, Pelin, Cincioğlu-Palabıyık, Mehtap, Çelik, Hande, Karahan, Hande

“…Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key…”
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Diabetes Alters Aromatase Enzyme Levels in Sciatic Nerve and Hippocampus Tissues of Rats by Burul-Bozkurt, Nihan, Pekiner, Can, Kelicen, Pelin

“…Diabetes mellitus (DM) is associated with increased risk of impaired cognitive function. Diabetic neuropathy is one of the most common and important…”
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Molecular docking and ex vivo and in vitro anticholinesterase activity studies of Salvia sp. and highlighted rosmarinic acid by Demirezer, Lütfiye Ömür, Gürbüz, Perihan, Kelicen Uğur, Emine Pelin, Bodur, Mine, Özenver, Nadire, Uz, Ayse, Güvenalp, Zühal

“…To evaluate acetylcholinesterase (AChE) inhibitory activity and antioxidant capacity of the major molecule from Salvia sp., rosmarinic acid, as a drug…”
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Lipopolysaccharide Induces CYP2E1 in Astrocytes through MAP Kinase Kinase-3 and C/EBPβ and -Πby Pelin Kelicen, Niclas Tindberg

“…Cytochrome P450 2E1 (CYP2E1) is highly inducible in a subset of astrocytes in vivo following ischemic or mechanical injury and in vitro by lipopolysaccharide…”
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Lipopolysaccharide Induces CYP2E1 in Astrocytes through MAP Kinase Kinase-3 and C/EBPβ and -δ by Kelicen, Pelin, Tindberg, Niclas

“…Cytochrome P450 2E1 (CYP2E1) is highly inducible in a subset of astrocytes in vivo following ischemic or mechanical injury and in vitro by lipopolysaccharide…”
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Cerliponase alfa decreases Aβ load and alters autophagy- related pathways in mouse hippocampal neurons exposed to fAβ1–42 by Kose, Selma, Cinar, Elif, Akyel, Hilal, Cakir-Aktas, Canan, Tel, Banu Cahide, Karatas, Hulya, Kelicen-Ugur, Pelin

“…Extracellular aggregation of amyloid-beta (Aβ) in the brain plays a central role in the onset and progression of Alzheimer's disease (AD). Moreover,…”
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AROMATASE INHIBITORS IN BREAST CANCER THERAPY by Hande Karahan, Emine Pelin Kelicen

“…Aromatase is an enzyme complex which is assigned in the last step of estrogen biosynthesis; it increases total estrogen levels by converting androgens to…”
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A[beta](25-35) Attenuated SREBP Level in Nuclear Extracts of Serum-Deprived Human Neuroblastoma Cells by Kelicen, Pelin, Cinciolu, Mehtap, Hizli, Fatih, Nordberg, Agneta

“…Disturbance in cholesterol homeostasis appears to be an important factor in the pathogenesis of neurodegenerative disorders. The aim of the present study was…”
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Abeta(25-35) attenuated SREBP level in nuclear extracts of serum-deprived human neuroblastoma cells by Kelicen, Pelin, Cincioğlu, Mehtap, Hizli, Fatih, Nordberg, Agneta

“…Disturbance in cholesterol homeostasis appears to be an important factor in the pathogenesis of neurodegenerative disorders. The aim of the present study was…”
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