Search Results - "Kelepouris, Nicky"

Coverage of education and training of traumatic brain injury-induced growth hormone deficiency in US residency and fellowship programs: a cross-sectional study by Cárdenas, Javier, Kelepouris, Nicky, Adiga, Radhika, Yuen, Kevin C J

“…Hypopituitarism, including growth hormone deficiency (GHD), is a common sequela of traumatic brain injury (TBI). This study explored the coverage of education…”
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Long-term treatment with pegvisomant as monotherapy in patients with acromegaly: experience from ACROSTUDY by Freda, Pamela U, Gordon, Murray B, Kelepouris, Nicky, Jonsson, Peter, Koltowska-Haggstrom, Maria, van der Lely, A J

“…To evaluate use of pegvisomant, a growth hormone (GH) receptor antagonist, as monotherapy in ACROSTUDY, a global safety surveillance study set in 14 countries…”
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Pregnancy outcomes in women receiving growth hormone replacement therapy enrolled in the NordiNet® International Outcome Study (IOS) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program by Biller, Beverly M. K., Höybye, Charlotte, Carroll, Paul, Gordon, Murray B., Birkegård, Anna Camilla, Kelepouris, Nicky, Nedjatian, Navid, Weber, Matthias M.

“…Purpose Data on the safety of growth hormone (GH) replacement therapy during pregnancy are limited. We report a combined analysis of data from pregnant women…”
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Cardiovascular safety of growth hormone treatment in Noonan syndrome: real-world evidence by Romano, Alicia, Kaski, Juan Pablo, Dahlgren, Jovanna, Kelepouris, Nicky, Pietropoli, Alberto, Rohrer, Tilman R, Polak, Michel

“…Objective The study aims to assess the cardiovascular safety of growth hormone (GH) treatment in patients with Noonan syndrome (NS) in clinical practice…”
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Outcomes in growth hormone-treated Noonan syndrome children: impact of PTPN11 mutation status by Jorge, Alexander A L, Edouard, Thomas, Maghnie, Mohamad, Pietropoli, Alberto, Kelepouris, Nicky, Romano, Alicia, Zenker, Martin, Horikawa, Reiko

“…Introduction Mutations in PTPN11 are associated with Noonan syndrome (NS). Although the effectiveness of growth hormone therapy (GHT) in treating short stature…”
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Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database by Yuen, Kevin C. J., Birkegard, Anna Camilla, Blevins, Lewis S., Clemmons, David R., Hoffman, Andrew R., Kelepouris, Nicky, Kerr, Janice M., Tarp, Jens M., Fleseriu, Maria

“…Objective. Adult growth hormone deficiency (AGHD) is an underdiagnosed disease associated with increased morbidity and mortality. Identifying people who may…”
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Reduced CV risk with long-term GH replacement in AGHD: data from two large observational studies by Höybye, Charlotte, Biller, Beverly M K, Ferran, Jean-Marc, Gordon, Murray B, Kelepouris, Nicky, Nedjatian, Navid, Olsen, Anne H, Weber, Matthias M

“…Adult growth hormone deficiency (AGHD) is associated with an increased risk of cardiovascular (CV) disease. Long-term growth hormone (GH) treatment could…”
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Sensitivity and specificity of the macimorelin test for diagnosis of AGHD by Garcia, Jose M, Biller, Beverly M K, Korbonits, Márta, Popovic, Vera, Luger, Anton, Strasburger, Christian J, Chanson, Philippe, Swerdloff, Ronald, Wang, Christina, Fleming, Rosa Rosanna, Cohen, Fredric, Ammer, Nicola, Mueller, Gilbert, Kelepouris, Nicky, Strobl, Frank, Ostrow, Vlady, Yuen, Kevin C J

“…Abstract Objective The macimorelin test is approved for the diagnosis of adult growth hormone deficiency (AGHD) based on its efficacy vs the insulin tolerance…”
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eP151: Outcomes in growth hormone-treated Noonan syndrome children: Impact of PTPN11 variant status by Jorge, Alexander, Pietropoli, Alberto, Kelepouris, Nicky, Horikawa, Reiko

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of macimorelin in healthy adults: Results of a single-dose, randomized controlled study by Klaus, Beate, Sachse, Richard, Ammer, Nicola, Kelepouris, Nicky, Ostrow, Vlady

“…Macimorelin is an orally active ghrelin receptor agonist indicated for the diagnosis of adult growth hormone (GH) deficiency in the United States. This phase 1…”
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Pediatric growth hormone deficiency: Understanding the patient and caregiver perspectives by Miller, Bradley S., Kelepouris, Nicky, Tenenbaum, Harlan, Di Carlo, Sonia, Backeljauw, Philippe

“…Childhood growth hormone deficiency (GHD) is a rare disorder associated with significant burden on both patients and caregivers. Although previous reports have…”
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Early Growth Hormone Initiation Leads to Favorable Long-Term Growth Outcomes in Children Born Small for Gestational Age by Juul, Anders, Backeljauw, Philippe, Cappa, Marco, Pietropoli, Alberto, Kelepouris, Nicky, Linglart, Agnès, Pfäffle, Roland, Geffner, Mitchell

“…Abstract Context Early initiation of growth hormone (GH) therapy is recommended for short children born small for gestational age (SGA); however, real-world…”
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THU008 Coverage Of Education And Training Of Traumatic Brain Injury-induced Growth Hormone Deficiency In US Endocrinology Fellowship Programs by Ji Yuen, Kevin Choong, Adiga, Radhika, Kelepouris, Nicky, Cardenas, Javier

“…Abstract Disclosure: K.C. Yuen: Advisory Board Member; Self; Novo Nordisk, Ascendis, Corcept, Ipsen, Amryt, Strongbridge, Crinetics, Recordati and Xeris. Grant…”
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Long-Term Safety of Growth Hormone Treatment in Childhood: Two Large Observational Studies: NordiNet IOS and ANSWER by Sävendahl, Lars, Polak, Michel, Backeljauw, Philippe, Blair, Joanne C, Miller, Bradley S, Rohrer, Tilman R, Hokken-Koelega, Anita, Pietropoli, Alberto, Kelepouris, Nicky, Ross, Judith

“…Abstract Context Growth hormone (GH) treatment has a generally good safety profile; however, concerns about increased mortality risk in adulthood have been…”
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Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program by Backeljauw, Philippe, Blair, Joanne C, Ferran, Jean-Marc, Kelepouris, Nicky, Miller, Bradley S, Pietropoli, Alberto, Polak, Michel, Sävendahl, Lars, Verlinde, Franciska, Rohrer, Tilman R

“…Abstract Context Despite having normal growth hormone (GH) secretion, individuals with Turner syndrome (TS) have short stature. Treatment with recombinant…”
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Insights from an advisory board: Facilitating transition of care into adulthood in brain cancer survivors with acquired pediatric growth hormone deficiency by Alter, Craig, Boguszewski, Margaret, Clemmons, David, Dobri, Georgiana A., Geffner, Mitchell E., Kelepouris, Nicky, Miller, Bradley S., Oh, Richard, Shea, Heidi, Yuen, Kevin C.J.

“…Children with growth hormone deficiency (GHD) face multiple challenges that can negatively impact the transition from pediatric to adult endocrinology care…”
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Effectiveness and Safety of Early Growth Hormone Treatment in Children Born Small for Gestational Age: Long-Term Data From NordiNet® International Outcome Study (IOS) and ANSWER Program by Juul, Anders, Pietropoli, Alberto, Kelepouris, Nicky, Geffner, Mitchell E

“…Abstract Background: Growth hormone (GH) is indicated for the treatment of short stature in children born small for gestational age (SGA) who fail to show…”
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Adult Growth Hormone Deficiency: Diagnostic and Treatment Journeys From the Patients’ Perspective by Hoffman, Andrew R, Mathison, Tracy, Andrews, Deno, Murray, Kristine, Kelepouris, Nicky, Fleseriu, Maria

“…Abstract Adult growth hormone deficiency (AGHD) is a rare and serious condition associated with significant morbidity, including reduced quality of life, and…”
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PMON60 Growth Hormone (GH) Replacement Therapy (GHRT) in Patients with Adult GH Deficiency (AGHD) Aged ≥60 Years: Data from NordiNet® IOS and the ANSWER Program by Biller, Beverly, Gordon, Murray, Höybye, Charlotte, Olsen, Anne, Kelepouris, Nicky, Nedjatian, Navid, Weber, Matthias

“…Abstract There are limited data on the effectiveness and safety of GHRT in older patients with AGHD. We compared real-world GHRT outcomes in older (aged ≥60…”
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Outcomes in children treated with growth hormone for Prader-Willi syndrome: data from the ANSWER Program® and NordiNet® International Outcome Study by Angulo, Moris, Abuzzahab, M. Jennifer, Pietropoli, Alberto, Ostrow, Vlady, Kelepouris, Nicky, Tauber, Maithe

“…Abstract Background Growth hormone (GH) deficiency is common in patients with Prader-Willi syndrome (PWS) and leads to short adult stature. The current study…”
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