Search Results - "Kelenis, Demetra P"

ASCL1 represses a SOX9 + neural crest stem-like state in small cell lung cancer by Olsen, Rachelle R, Ireland, Abbie S, Kastner, David W, Groves, Sarah M, Spainhower, Kyle B, Pozo, Karine, Kelenis, Demetra P, Whitney, Christopher P, Guthrie, Matthew R, Wait, Sarah J, Soltero, Danny, Witt, Benjamin L, Quaranta, Vito, Johnson, Jane E, Oliver, Trudy G

“…ASCL1 is a neuroendocrine lineage-specific oncogenic driver of small cell lung cancer (SCLC), highly expressed in a significant fraction of tumors. However,…”
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Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs by Geis, Franziska K, Kelenis, Demetra P, Goff, Stephen P

“…Mammalian cells mount a variety of defense mechanisms against invading viruses to prevent or reduce infection. One such defense is the transcriptional…”
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ASCL1 regulates proliferation of NG2‐glia in the embryonic and adult spinal cord by Kelenis, Demetra P., Hart, Emma, Edwards‐Fligner, Morgan, Johnson, Jane E., Vue, Tou Yia

“…NG2‐glia are highly proliferative oligodendrocyte precursor cells (OPCs) that are widely distributed throughout the central nervous system (CNS). During…”
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ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer by Pozo, Karine, Kollipara, Rahul K., Kelenis, Demetra P., Rodarte, Kathia E., Ullrich, Morgan S., Zhang, Xiaoyang, Minna, John D., Johnson, Jane E.

“…Lineage-defining transcription factors (LTFs) play key roles in small-cell lung cancer (SCLC) pathophysiology. Delineating the LTF-regulated genes operative in…”
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Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer by Kelenis, Demetra P, Rodarte, Kathia E, Kollipara, Rahul K, Pozo, Karine, Choudhuri, Shreoshi Pal, Spainhower, Kyle B, Wait, Sarah J, Stastny, Victor, Oliver, Trudy G, Johnson, Jane E

“…Genomic studies support the classification of small cell lung cancer (SCLC) into subtypes based on the expression of lineage-defining transcription factors…”
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A central role for the primary microRNA stem in guiding the position and efficiency of Drosha processing of a viral pri-miRNA by Burke, James M, Kelenis, Demetra P, Kincaid, Rodney P, Sullivan, Christopher S

“…Processing of primary microRNA (pri-miRNA) stem-loops by the Drosha-DGCR8 complex is the initial step in miRNA maturation and crucial for miRNA function…”
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ASCL 1 regulates proliferation of NG 2‐glia in the embryonic and adult spinal cord by Kelenis, Demetra P., Hart, Emma, Edwards‐Fligner, Morgan, Johnson, Jane E., Vue, Tou Yia

“…NG2‐glia are highly proliferative oligodendrocyte precursor cells (OPCs) that are widely distributed throughout the central nervous system (CNS). During…”
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