Search Results - "Keleş, Sevgi"

CD19 EKSİKLİĞİ TANISINDA RFLP YÖNTEMİNİN KULLANIMI by EFE, Hatice, KARASELEK, Mehmet, KAPAKLI, Hasan, GÜL, Yahya, KELEŞ, Sevgi, GÜNER, Şükrü, KURAR, Ercan, REİSLİ, İsmail

“…B lenfosit yüzeyinde bulunan CD19 molekülü olgun B hücrelerinde CD21, CD81, CD225 ile birlikte CD19 kompleksini oluşturur ve antijen uyarısı ile birlikte B…”
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Hematopoietic stem cell transplantation in serine/threonine kinase 4 (STK4) deficiency: Report of two cases and literature review by Uygun, Vedat, Keleş, Sevgi, Daloğlu, Hayriye, Öztürkmen, Seda, Yalçın, Koray, Karasu, Gülsün, Yeşilipek, Akif

“…Background Serine/threonine kinase 4 (STK4) deficiency is a combined immunodeficiency (CID) characterized by early onset recurrent bacterial, viral, and fungal…”
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Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA by Charbonnier, Louis-Marie, PhD, Janssen, Erin, MD, PhD, Chou, Janet, MD, Ohsumi, Toshiro K., PhD, Keles, Sevgi, MD, Hsu, Joyce T., MD, Massaad, Michel J., PhD, Garcia-Lloret, Maria, MD, Hanna-Wakim, Rima, MD, Dbaibo, Ghassan, MD, Alangari, Abdullah A., MD, Alsultan, Abdulrahman, MD, Al-Zahrani, Daifulah, MD, Geha, Raif S., MD, Chatila, Talal A., MD, MSc

“…Background A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They…”
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Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation by Keles, Sevgi, Charbonnier, Louis Marie, Kabaleeswaran, Venkataraman, Reisli, Ismail, Genel, Ferah, Gulez, Nesrin, Al-Herz, Waleed, Ramesh, Narayanaswamy, Perez-Atayde, Antonio, Karaca, Neslihan E., Kutukculer, Necil, Wu, Hao, Geha, Raif S., Chatila, Talal A.

“…The autosomal recessive hyper-IgE syndrome (HIES) caused by dedicator of cytokinesis 8 (DOCK8) deficiency shares clinical features with autosomal dominant HIES…”
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Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations by Zemmour, David, Charbonnier, Louis-Marie, Leon, Juliette, Six, Emmanuelle, Keles, Sevgi, Delville, Marianne, Benamar, Mehdi, Baris, Safa, Zuber, Julien, Chen, Karin, Neven, Benedicte, Garcia-Lloret, Maria I., Ruemmele, Frank M., Brugnara, Carlo, Cerf-Bensussan, Nadine, Rieux-Laucat, Frederic, Cavazzana, Marina, André, Isabelle, Chatila, Talal A., Mathis, Diane, Benoist, Christophe

“…FOXP3 deficiency in mice and in patients with immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome results in fatal autoimmunity by…”
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Successful treatment of postinfectious bronchiolitis obliterans with gamma globulin in a tertiary center: 10 years of experience by Yilmaz, Aslı İmran, Gül, Yahya, Kapaklı, Hasan, Ünal, Gökçen, Çağlar, Hanife Tuğçe, Ercan, Fatih, Reisli, İsmail, Keleş, Sevgi, Poyraz, Necdet, Pekcan, Sevgi

“…Introduction Bronchiolitis obliterans is characterized by partial or total occlusion of the bronchioles due to inflammation and fibrosis, and the most common…”
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Lenz-Majewski syndrome and recurrent otitis media: Are they related or not? by Maden Bedel, Fayize, Balasar, Özgür, Erol Aytekin, Selma, Keleş, Sevgi, Çaksen, Hüseyin

“…Lenz-Majewski hyperostotic dwarfism (LMHD) is a rare condition characterized by intellectual disability, sclerosing bone dysplasia, dysmorphic facial features,…”
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Memory B cells and serum immunoglobulins are associated with disease severity and mortality in patients with COVID-19 by Çölkesen, Fatih, Kepenek Kurt, Esma, Vatansev, Hülya, Korkmaz, Celalettin, Çölkesen, Fatma, Yücel, Fatih, Yıldız, Eray, Evcen, Recep, Aykan, Filiz Sadi, Kılınç, Mehmet, Aytekin, Gökhan, Feyzioğlu, Bahadır, Doğan, Metin, Arslan, Şevket, Teke, Turgut, Keleş, Sevgi, Reisli, İsmail

“…Purpose of the studyThe aim of this study was to investigate the relationship of B cell-mediated immunity with disease severity and mortality in patients with…”
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A novel approach in allergen-specific immunotherapy: Combination of sublingual and subcutaneous routes by Keles, Sevgi, MD, Karakoc-Aydiner, Elif, MD, Ozen, Ahmet, MD, Izgi, Ayse Gul, MS, Tevetoglu, Ayzer, MS, Akkoc, Tunc, PhD, Bahceciler, Nerin N., MD, Barlan, Isil, MD

“…Background Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of action, whereas repeated injections and safety concerns have limited its…”
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Evaluation of the 10 Warning Signs in Primary and Secondary Immunodeficient Patients by Eldeniz, Fadime Ceyda, Gul, Yahya, Yorulmaz, Alaaddin, Guner, Sukru Nail, Keles, Sevgi, Reisli, Ismail

“…Ten warning signs of primary immunodeficiency (PID) were suggested by the Jeffrey Modell Foundation (JMF), to increase physician awareness of PID. These…”
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DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation by Jabara, Haifa H, McDonald, Douglas R, Janssen, Erin, Massaad, Michel J, Ramesh, Narayanaswamy, Borzutzky, Arturo, Rauter, Ingrid, Benson, Halli, Schneider, Lynda, Baxi, Sachin, Recher, Mike, Notarangelo, Luigi D, Wakim, Rima, Dbaibo, Ghassan, Dasouki, Majed, Al-Herz, Waleed, Barlan, Isil, Baris, Safa, Kutukculer, Necil, Ochs, Hans D, Plebani, Alessandro, Kanariou, Maria, Lefranc, Gerard, Reisli, Ismail, Fitzgerald, Katherine A, Golenbock, Douglas, Manis, John, Keles, Sevgi, Ceja, Reuben, Chatila, Talal A, Geha, Raif S

“…Dock8 deficiency leads to defects in humoral immunity. Geha and colleagues show that Dock88 interacts with MyD88 to bridge TLR9 signaling to the Src-Syk-STAT3…”
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Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome by Engelhardt, Karin R., Dr, McGhee, Sean, MD, Winkler, Sabine, MSc, Sassi, Atfa, PhD, Woellner, Cristina, MSc, Lopez-Herrera, Gabriela, PhD, Chen, Andrew, Kim, Hong Sook, PhD, Lloret, Maria Garcia, MD, Schulze, Ilka, MD, Ehl, Stephan, MD, Thiel, Jens, MD, Pfeifer, Dietmar, Dr, Veelken, Hendrik, MD, Niehues, Tim, MD, Siepermann, Kathrin, MD, Weinspach, Sebastian, MD, Reisli, Ismail, MD, Keles, Sevgi, MD, Genel, Ferah, MD, Kutuculer, Necil, MD, Camcoğlu, Yldz, MD, Somer, Ayper, MD, Karakoc-Aydiner, Elif, MD, Barlan, Isil, MD, Gennery, Andrew, MD, Metin, Ayse, MD, PhD, Degerliyurt, Aydan, MD, Pietrogrande, Maria C., MD, Yeganeh, Mehdi, MD, Baz, Zeina, MD, Al-Tamemi, Salem, MD, Klein, Christoph, MD, PhD, Puck, Jennifer M., MD, Holland, Steven M., MD, McCabe, Edward R.B., MD, PhD, Grimbacher, Bodo, MD, Chatila, Talal A., MD, MSc

“…Background The genetic etiologies of the hyper-IgE syndromes are diverse. Approximately 60% to 70% of patients with hyper-IgE syndrome have dominant mutations…”
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Long-Term Experience of Subcutaneous Immunoglobulin Therapy in Pediatric Primary Immunodeficient Patients with Low and Normal Body Weight by Gul, Yahya, Kapakli, Hasan, Guner, Sukru Nail, Alan, Havva Bozkurt, Hazar, Esra, Keles, Sevgi, Reisli, Ismail

“…Purpose The aim was to review the compliance, side effects and effectiveness of subcutaneous immunoglobulin (SCIG) supplementation in patients with primary…”
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Clinical and laboratory evaluation of Turkish children with IgG subclass deficiency by Kocaoğlu, Mehmet, Kocaoğlu, Burcu Ezgi, Erol Aytekin, Selma, Keskin, Doğukan Mustafa, Güner, Şükrü Nail, Keleş, Sevgi, Reisli, İsmail

“…IgG subclass deficiency is a laboratory diagnosis and becomes important with recurrent infections. This study aimed to examine the demographic, clinical, and…”
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Dedicator of cytokinesis 8–deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells by Janssen, Erin, MD, PhD, Morbach, Henner, MD, Ullas, Sumana, MS, Bannock, Jason M., MA, Massad, Christopher, BS, Menard, Laurence, PhD, Barlan, Isil, MD, Lefranc, Gerard, PhD, Su, Helen, MD, PhD, Dasouki, Majed, MD, Al-Herz, Waleed, MD, Keles, Sevgi, MD, Chatila, Talal, MD, Geha, Raif S., MD, Meffre, Eric, PhD

“…Background Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE levels, eosinophilia, and a high incidence of…”
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Immunological mechanism of postherpetic neuralgia and effect of pregabalin treatment on the mechanism: a prospective single-arm observational study by Mercan, Aysel, Uzun, Sema Tuncer, Keles, Sevgi, Hacibeyoglu, Gulcin, Yilmaz, Resul, Reisli, Ruhiye

“…Although neuropathic pain is a severe and common pain, its pathophysiology has not been elucidated yet. Studies in recent years have focused on the immune…”
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Newborn screening for SCID: the very first prospective pilot study from Türkiye by Haskologlu, Sule, Kocak, Senem, Tufan, Lale Satiroglu, Aksoy, Fethiye Eken, Bastug, Dilan, Oner, Deniz Aslar, Islamoglu, Candan, Baskin, Kubra, Esenboga, Saliha, Acican, Deniz, Ceylaner, Serdar, Guner, Sukru Nail, Keles, Sevgi, Cagdas, Deniz, Reisli, Ismail, Tezel, Basak, Dogu, Figen, Tezcan, Ilhan, Ikinciogullari, Aydan

“…The measurement of T-cell receptor excision circle (TREC) is used for newborn screening (NBS) in dried blood spot (DBS) samples from Guthrie card for severe…”
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Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease by DeVore, Stanley B., Schuetz, Matthew, Alvey, Lauren, Lujan, Henry, Ochayon, David E., Williams, Lindsey, Chang, Wan Chi, Filuta, Alyssa, Ruff, Brandy, Kothari, Arjun, Hahn, Jennifer M., Brandt, Eric, Satish, Latha, Roskin, Krishna, Herr, Andrew B., Biagini, Jocelyn M., Martin, Lisa J., Cagdas, Deniz, Keles, Sevgi, Milner, Joshua D., Supp, Dorothy M., Khurana Hershey, Gurjit K.

“…Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic…”
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ILC3 deficiency and generalized ILC abnormalities in DOCK8‐deficient patients by Eken, Ahmet, Cansever, Murat, Okus, Fatma Zehra, Erdem, Serife, Nain, Ercan, Azizoglu, Zehra Busra, Haliloglu, Yesim, Karakukcu, Musa, Ozcan, Alper, Devecioglu, Omer, Aksu, Guzide, Arikan Ayyildiz, Zeynep, Topal, Erdem, Karakoc Aydiner, Elif, Kiykim, Ayca, Metin, Ayse, Cipe, Funda, Kaya, Aysenur, Artac, Hasibe, Reisli, Ismail, Guner, Sukru N., Uygun, Vedat, Karasu, Gulsun, Dönmez Altuntas, Hamiyet, Canatan, Halit, Oukka, Mohamed, Ozen, Ahmet, Chatila, Talal A., Keles, Sevgi, Baris, Safa, Unal, Ekrem, Patiroglu, Turkan

“…Background Dedicator of cytokinesis 8 (DOCK8) deficiency is the main cause of the autosomal recessive hyper‐IgE syndrome (HIES). We previously reported the…”
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Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency by Al-Herz, Waleed, MD, Chu, Julia I., MD, van der Spek, Jet, BSc, Raghupathy, Raj, PhD, Massaad, Michel J., PhD, Keles, Sevgi, MD, Biggs, Catherine M., MD, Cockerton, Lucinda, MSc, Chou, Janet, MD, Dbaibo, Ghassan, MD, Elisofon, Scott A., MD, Hanna-Wakim, Rima, MD, Kim, Heung Bae, MD, Lehmann, Leslie E., MD, McDonald, Douglas R., MD, PhD, Notarangelo, Luigi D., MD, Veys, Paul, MD, Chatila, Talal A., MD, Geha, Raif S., MD, Gaspar, H. Bobby, MD, Pai, Sung-Yun, MD

“…Background Dedicator of cytokinesis 8 (DOCK8) deficiency can be cured by allogeneic hematopoietic stem cell transplantation (HSCT). Reports of outcomes are…”
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