Search Results - "Kelbaugh, Paul R"

2-Thioalkyl penems: an efficient synthesis of sulopenem, a (5R,6S)-6-(1(R)-hydroxyethyl)-2-[(cis-1-oxo-3-thiolanyl)thio]-2-penem antibacterial by Volkmann, Robert A, Kelbaugh, Paul R, Nason, Deane M, Jasys, V. John

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Isolation, structure elucidation, and synthesis of novel hydroxylamine-containing polyamines from the venom of the Agelenopsis aperta spider by Jasys, V. John, Kelbaugh, Paul R, Nason, Deane M, Phillips, Douglas, Rosnack, Kenneth J, Saccomano, Nicholas A, Stroh, Justin G, Volkmann, Robert A

“…Novel hydroxylamine-containing polyamines have been isolated from the venom of Agelenopsis aperta , a funnel-web spider found throughout the western United…”
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Disulfide Bond Assignment of .omega.-Agatoxins IVB and IVC: Discovery of a D-Serine Residue in .omega.-Agatoxin IVB by Heck, Steven D, Kelbaugh, Paul R, Kelly, Mary E, Thadeio, Peter F, Saccomano, Nicholas A, Stroh, Justin G, Volkmann, Robert A

“…A TCEP (tris(2-carboxyethyl)phosphine)-based reduction/cysteine amidoalkylation strategy was utilized to solve the disulfide structures of omega -agatoxins IVB…”
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Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels by Sanguinetti, M C, Johnson, J H, Hammerland, L G, Kelbaugh, P R, Volkmann, R A, Saccomano, N A, Mueller, A L

“…Toxins isolated from scorpion, snake, and spider venoms are valuable tools to probe the physiologic function and structure of ion channels. In this study, we…”
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Novel quaternary ammonium salt-containing polyamines from the Agelenopsis aperta funnel-web spider by Jasys, V. John, Kelbaugh, Paul R, Nason, Deane M, Phillips, Douglas, Rosnack, Kenneth J, Saccomano, Nicholas A, Stroh, Justin G, Volkmann, Robert A, Forman, James T

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Posttranslational Amino Acid Epimerization: Enzyme-Catalyzed Isomerization of Amino Acid Residues in Peptide Chains by Heck, Steven D., Faraci, W. Stephen, Kelbaugh, Paul R., Saccomano, Nicholas A., Thadeio, Peter F., Volkmann, Robert A.

“…Since ribosomally mediated protein biosynthesis is confined to the L-amino acid pool, the presence of D-amino acids in peptides was considered for many years…”
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Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors by Rizzi, James P, Schnur, Rodney C, Hutson, Nancy J, Kraus, Kenneth G, Kelbaugh, Paul R

“…Sorbinil (1), a spirocyclic hydantoin, is a potent inhibitor of the enzyme aldose reductase. Simulation of the rigid spirocyclic ring orientation found in…”
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Synthesis of optically active spirohydantoins by asymmetric induction. Hydantoin formation from amino nitriles and chlorosulfonyl isocyanates by Sarges, Reinhard, Howard, Harry R, Kelbaugh, Paul R

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Functional Consequences of Posttranslation Isomerization of Ser$^{46}$ in a Calcium Channel Toxin by Heck, Steven D., Siok, Chester J., Krapcho, Karen J., Kelbaugh, Paul R., Thadeio, Peter F., Welch, Melissa J., Williams, Robert D., Ganong, Alan H., Kelly, Mary E., Lanzetti, Anthony J., Gray, William R., Phillips, Douglas, Parks, Thomas N., Jackson, Hunter, Ahlijanian, Michael K., Saccomano, Nicholas A., Volkmann, Robert A.

“…The venom of the funnel-web spider Agelenopsis aperta contains several peptides that paralyze prey by blocking voltage-sensitive calcium channels. Two…”
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Functional Consequences of Posttranslational Isomerization of Ser 46 in a Calcium Channel Toxin by Heck, Steven D., Siok, Chester J., Krapcho, Karen J., Kelbaugh, Paul R., Thadeio, Peter F., Welch, Melissa J., Williams, Robert D., Ganong, Alan H., Kelly, Mary E., Lanzetti, Anthony J., Gray, William R., Phillips, Douglas, Parks, Thomas N., Jackson, Hunter, Ahlijanian, Michael K., Saccomano, Nicholas A., Volkmann, Robert A.

“…The venom of the funnel-web spider Agelenopsis aperta contains several peptides that paralyze prey by blocking voltage-sensitive calcium channels. Two…”
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Functional consequences of posttranslational isomerization of Ser46 in a calcium channel toxin by HECK, S. D, SIOK, C. J, GRAY, W. R, PHILLIPS, D, PARKS, T. N, JACKSON, H, AHLIJANIAN, M. K, SACCOMANO, N. A, VOLKMANN, R. A, KRAPCHO, K. J, KELBAUGH, P. R, THADEIO, P. F, WELCH, M. J, WILLIAMS, R. D, GANONG, A. H, KELLY, M. E, LANZETTI, A. J

“…The venom of the funnel-web spider Agelenopsis aperta contains several peptides that paralyze prey by blocking voltage-sensitive calcium channels. Two…”
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