Search Results - "Kelani, Khadiga M"
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Innovative voltammetric techniques for bumadizone analysis in pharmaceutical and biological samples: emphasizing green, white, and blue analytical approaches
Published in Scientific reports (27-08-2024)“…There are no documented electroanalytical methods for quantifying the anti-inflammatory drug bumadizone (BUM) in pharmaceutical or biological matrices. So, a…”
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Advanced chemometric methods for simultaneous quantitation of caffeine, codeine, paracetamol, and p-aminophenol in their quaternary mixture
Published in Scientific reports (24-01-2024)“…Two different multivariate techniques have been applied for the quantitative analysis of caffeine, codeine, paracetamol and p-aminophenol (PAP) in quaternary…”
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Application of multivariate chemometrics tools for spectrophotometric determination of naphazoline HCl, pheniramine maleate and three official impurities in their eye drops
Published in Scientific reports (11-11-2023)“…This work is concerned with exploiting the power of chemometrics in the assay and purity determination of naphazoline HCl (NZ) and pheniramine maleate (PN) in…”
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Comparing the predictability of different chemometric models over UV-spectral data of isoxsuprine and its toxic photothermal degradation products
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-08-2019)“…Isoxsuprine (ISX) is widely used for cerebral and peripheral vascular diseases. A comparative study was held among different multivariate calibration models…”
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Inline potentiometric monitoring of Butyrylcholinesterase activity based on metabolism of bambuterol at the point of care
Published in Sensors and actuators. B, Chemical (15-04-2019)“…[Display omitted] •Butyrylcholinesterase enzyme (BChE) hydrolyzes succinylcholine and other neuromuscular blockers.•These drugs are used for rapid induction of…”
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Design of point-of-care electrochemical sensor for therapeutic drug monitoring of ofloxacin in biological fluids
Published in Journal of analytical science and technology (01-12-2024)“…A disposable screen-printed sensor has been crafted specifically for therapeutic drug monitoring purposes, particularly for detecting ofloxacin in biological…”
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Three developed spectrophotometric methods for determination of a mixture of ofloxacin and ornidazole; application of greenness assessment tools
Published in BMC chemistry (13-03-2023)“…This work is dedicated to the greenness estimation of three proposed spectrophotometric techniques [e.g., ratio difference (RD), mean centering of ratio…”
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Continuous wavelet transform for solving the problem of minor components in quantitation of pharmaceuticals: a case study on the mixture of ibuprofen and phenylephrine with its degradation products
Published in BMC chemistry (24-10-2023)“…The presence of minor components represents a challenging problem in spectrophotometric analysis of pharmaceuticals. If one component has a low absorptivity or…”
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A green TLC densitometric method for the simultaneous detection and quantification of naphazoline HCl, pheniramine maleate along with three official impurities
Published in BMC chemistry (04-04-2022)“…Impurity profiling of a pharmaceutical compound is now taking great attention during quality assessment of pharmaceuticals, as presence of small amount of…”
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Comparing silver and gold nanoislands’ surface plasmon resonance for bisacodyl and its metabolite quantification in human plasma
Published in BMC chemistry (23-03-2024)“…Gold and silver nanoparticles have witnessed increased scientific interest due to their colourful colloidal solutions and exceptional applications. Comparing…”
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Comparative study of extension area based methods for spectrophotometric determination of desmopressin acetate in the presence of its acid-induced degradation products
Published in BMC chemistry (18-12-2022)“…Desmopressin acetate (DPA) is a synthetic analogue of vasopressin used in the treatment of diabetes insipidus, bedwetting, hemophilia A, and elevated levels of…”
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Development of an eco-friendly HPLC method for the stability indicating assay of binary mixture of ibuprofen and phenylephrine
Published in BMC chemistry (24-10-2023)“…The development and validation of the stability indicating HPLC technique has contributed to the understanding of the stability profile of ibuprofen (IBU) and…”
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Chromatographic reversed HPLC and TLC-densitometry methods for simultaneous determination of serdexmethylphenidate and dexmethylphenidate in presence of their degradation products—with computational assessment
Published in BMC chemistry (15-07-2023)“…Two Chromatographic methods have been established and optimized for simultaneous determination of serdexmethylphenidate (SER.DMP) and dexmethylphenidate (DMP)…”
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The simultaneous measurement of quaternary mixture in over-the-counter cold medications using sequential spectrophotometric resolution approach enhanced with in-lab sample enrichment
Published in BMC chemistry (22-03-2023)“…A sequential spectrophotometric resolution technique (SSRT) was developed in this study without the use of systematic separation procedures to determine drug…”
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Molecular imprinted polymer-based potentiometric approach for the assay of the co-formulated tetracycline HCl, metronidazole and bismuth subcitrate in capsules and spiked human plasma
Published in Analytica chimica acta (16-10-2023)“…An anti-H-pylori co-formulated mixture of tetracycline HCl (TET), metronidazole (MET), and bismuth subcitrate (BSC) is recently available. Only two…”
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Univariate versus multivariate spectrophotometric methods for the simultaneous determination of omarigliptin and two of its degradation products
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-04-2022)“…[Display omitted] •Omarigliptin was liable to hydrolytic and oxidative degradations.•Novel stability indicating spectrophotometric methods were developed.•Four…”
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A probe of new molecularly imprinted solid-phase extraction coupled with HPLC-DAD and atomic absorption spectrophotometry for quantification of tetracycline HCl, metronidazole and bismuth subcitrate in combination with their official impurities: Application in dosage form and human plasma
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-02-2024)“…•Tetracycline HCl, metronidazole and bismuth subcitrate have been combined recently.•An analytical approach for simultaneous determination of these drugs in…”
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TLC-smartphone in antibiotics determination and low-quality pharmaceuticals detection
Published in RSC advances (26-05-2021)“…Thin layer chromatography (TLC) is a powerful and simple technique for screening and quantifying low quality and counterfeit pharmaceutical products. The…”
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Surface enhanced infrared absorption spectroscopy (SEIRA) as a green analytical chemistry approach: Coating of recycled aluminum TLC sheets with citrate capped silver nanoparticles for chemometric quantitative analysis of ternary mixtures as a green alternative to the traditional methods
Published in Analytica chimica acta (22-06-2020)“…The past two decades have seen the full expansion of all fields of Nanotechnology, Chemometrics, Recycling, and Vibration spectroscopy into most of the…”
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Determination of pioglitazone, its metabolite and alogliptin in human plasma by a novel LC-MS/MS method; application to a pharmacokinetic study
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-11-2019)“…A novel, high throughput and sensitive LC-MS/MS assay method was developed and fully validated for quantitative determination of pioglitazone, its hydroxyl…”
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