Search Results - "Keks, Nicholas"

Lemborexant, an orexin receptor antagonist sedative-hypnotic: Is it useful for insomnia in psychiatric disorders? by Keks, Nicholas A, Hope, Judy

“…Objective Lemborexant, an orexin receptor antagonist similar to suvorexant, has been approved for the treatment of sleep onset and/or maintenance insomnia…”
Get full text

Cariprazine: A new partial dopamine agonist with a familiar profile by Hope, Judy, Keks, Nicholas A

“…Objective Cariprazine is the third partial dopamine agonist now available in Australia. This paper will review the properties, evidence and likely clinical…”
Get full text

What clinicians need to know about intranasal esketamine for treatment-resistant depression? by Hope, Judy, Copolov, David, Tiller, John, Galbally, Megan, Hopwood, Malcolm, Newton, Richard, Keks, Nicholas A

“…Objective To review the usefulness of esketamine for treatment-resistant depression. Method Pivotal trials of intranasal esketamine in treatment-resistant…”
Get full text

Brexpiprazole: a new leaf on the partial dopamine agonist branch by Hope, Judy, Castle, David, Keks, Nicholas A

“…Objectives: Brexpiprazole is a new dopamine partial agonist antipsychotic in the same class as aripiprazole. This paper will briefly review brexpiprazole and…”
Get full text

Association between long-term use of prolactin-elevating antipsychotics in women and the risk of breast cancer: What are the clinical implications? by Hope, Judith D, Keks, Nicholas A, Copolov, David L

“…Background Some antipsychotic drugs elevate prolactin, and hyperprolactinaemia is associated with an increased risk of breast cancer. Women with schizophrenia…”
Get full text

Suvorexant: scientifically interesting, utility uncertain by Keks, Nicholas A, Hope, Judy, Keogh, Simone

“…Objective: Suvorexant, a new hypnotic, is indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance, and…”
Get full text

Characteristics, diagnoses, illness course and risk profiles of inpatients admitted for at least 21 days to an Australian private psychiatric hospital by Keks, Nicholas A, Hope, Judy, Pring, William, Damodaran, Saji, Varma, Shashjit, Adamopoulos, Voula

“…Objectives: To perform a clinical and risk audit of private hospital inpatients staying in hospital at least 21 days. Methods: Of 492 admissions for ≥21 days…”
Get full text

Long-acting injectable risperidone v. olanzapine tablets for schizophrenia or schizoaffective disorder: Randomised, controlled, open-label study by KEKS, NICHOLAS A, INGHAM, MICHAEL, KHAN, AKBAR, KARCHER, KEITH

“…The efficacy and safety of long-acting injectable risperidone have not been compared with those of an oral atypical antipsychotic. To compare long-acting…”
Get full text

Comparison of inpatients who were readmitted within 28 days of discharge with those not readmitted: an audit at an Australian private psychiatric hospital by Hope, Judith, Keks, Nicholas A, Pring, William, Adamopoulos, Voula, Toffler, David, Macfarlane, Stephen, Van Sebille, Debbie

“…Objective: To compare inpatients who had been readmitted within 28 days of discharge with patients not readmitted within the same period in a private…”
Get full text

Milnacipran: serotonin-noradrenaline reuptake inhibitor approved for fibromyalgia may be a useful antidepressant by Keks, Nicholas A, Hope, Judy, Keogh, Simone, Copolov, David L

“…Objective: Milnacipran is a serotonin noradrenaline reuptake inhibitor (SNRI) approved for treatment of fibromyalgia in Australia, but is used for depression…”
Get full text

Management of antidepressant-induced sexual dysfunction by Keks, Nicholas A, Hope, Judy, Culhane, Christine

“…Objective: Antidepressant-induced sexual dysfunction is a common, troublesome complication of antidepressant treatment that patients often fail to report,…”
Get full text

Characteristics, diagnoses and risk profiles of inpatients readmitted within 28 days of discharge to an Australian private psychiatric hospital by Keks, Nicholas A, Hope, Judith, Adamopoulos, Voula, Pring, William, Tofler, David, Macfarlane, Stephen, Van Sebille, Debbie

“…Objective: The objective of this study was to perform a clinical and risk audit of private hospital inpatients who had been readmitted within 28 days of a…”
Get full text

AN OPEN, RANDOMIZED, CONTROLLED COMPARISON OF LONG-ACTING INJECTABLE RISPERIDONE VS. ORAL OLANZAPINE IN SCHIZOPHRENIA & SCHIZOAFFECTIVE DISORDER by Keks, Nicholas A

Get full text

Lurasidone: an antipsychotic with antidepressant effects in bipolar depression? by Keks, Nicholas A, Hope, Judy, Castle, David

“…Objective: Lurasidone is a new serotonin–dopamine antagonist atypical antipsychotic which also appears to be effective in bipolar depression. This paper will…”
Get full text

Should ketamine be used for the clinical treatment of depression? by Arunogiri, Shalini, Keks, Nicholas A, Hope, Judy

“…Objective: There has been widespread interest from the public and media in the potential of ketamine as a novel treatment for depression. This paper reviews…”
Get full text

Aripiprazole long-acting injection: promising but more evidence needed by Keks, Nicholas A, Hope, Judy, Culhane, Christine

“…Objective: Aripiprazole long acting injection (ALAI) is now available, and this paper aims to assist clinicians in deciding when to use ALAI. Conclusion:…”
Get full text

Paliperidone palmitate three-month depot formulation: a helpful innovation with practical pitfalls by Hope, Judith D, Keks, Nicholas A

“…Objective: Paliperidone palmitate is now available as a three-month depot injection. This paper will review the pharmacokinetics, pharmacodynamics, efficacy…”
Get full text

Vortioxetine: A multimodal antidepressant or another selective serotonin reuptake inhibitor? by Keks, Nicholas A, Hope, Judy, Culhane, Christine

“…Objective: The treatment of depressive disorders remains unsatisfactory for many patients with regard to efficacy and tolerability. Vortioxetine has been…”
Get full text

Evaluation of Treatment in 35 Cases of Bipolar Suicide by Keks, Nicholas A., Hill, Christine, Sundram, Suresh, Graham, Annette, Bellingham, Kylee, Dean, Brian, Opeskin, Ken, Dorissa, Arrigo, Copolov, David L.

“…Objective: The aim of the present study was to evaluate clinical factors relevant to suicide prevention (including treatment) in cases of bipolar suicide with…”
Get full text

Beyond the evidence: is there a place for antidepressant combinations in the pharmacotherapy of depression? by Keks, Nicholas A, Burrows, Graham D, Copolov, David L, Newton, Richard, Paoletti, Nick, Schweitzer, Isaac, Tiller, John

“…Up to 45% of patients with debilitating and potentially lethal depressive illness do not achieve remission with initial drug treatment. Using combinations of…”
Get full text