Search Results - "Kekesi, Orsolya"
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Extensive astrocyte synchronization advances neuronal coupling in slow wave activity in vivo
Published in Scientific reports (20-07-2017)“…Slow wave activity (SWA) is a characteristic brain oscillation in sleep and quiet wakefulness. Although the cell types contributing to SWA genesis are not yet…”
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2
Method for Prolonged Incubation of Brain Slices
Published in Bio-protocol (20-07-2020)“…Slices of neuronal tissue maintain a high degree of topographical and functional properties of neurons and glia and therefore are extensively used for…”
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3
Calcium Imaging of AM Dyes Following Prolonged Incubation in Acute Neuronal Tissue
Published in PloS one (16-05-2016)“…Calcium-imaging is a sensitive method for monitoring calcium dynamics during neuronal activity. As intracellular calcium concentration is correlated to…”
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4
Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate
Published in Neuropharmacology (15-10-2021)“…Excitatory and inhibitory neurotransmission within the spinal dorsal horn is tightly controlled to regulate transmission of nociceptive signals to the brain…”
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5
Astrocytic modulation of neuronal excitability through K+ spatial buffering
Published in Neuroscience and biobehavioral reviews (01-06-2017)“…•This year marks the 50th anniversary to the potassium spatial buffering hypothesis.•Astrocytes using their K+ clearance capabilities to modulate neuronal…”
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Astrocytes convert network excitation to tonic inhibition of neurons
Published in BMC biology (15-03-2012)“…Glutamate and γ-aminobutyric acid (GABA) transporters play important roles in balancing excitatory and inhibitory signals in the brain. Increasing evidence…”
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7
Assessing toxicity of polyamidoamine dendrimers by neuronal signaling functions
Published in Nanotoxicology (01-09-2012)“…Abstract We report for the first time on neuronal signaling for the evaluation of interactions between native plasmamembrane and polyamidoamine (PAMAM)…”
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8
Neuromodulation of Astrocytic K + Clearance
Published in International journal of molecular sciences (03-03-2021)“…Potassium homeostasis is fundamental for brain function. Therefore, effective removal of excessive K+ from the synaptic cleft during neuronal activity is…”
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Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis
Published in Cell death & disease (05-04-2019)“…Amyotrophic lateral sclerosis (ALS) is a type of motor neuron disease (MND) in which humans lose motor functions due to progressive loss of motoneurons in the…”
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10
Cross-species Blink Characterisation Tool for the Analysis of Emerging Interventions for Overcoming Facial Paralysis
Published in 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-01-2023)“…The loss of the ability to blink is considered the most severe consequence of facial nerve paralysis. Surgical techniques and implantable technologies continue…”
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11
The differential impact of acute microglia activation on the excitability of cholinergic neurons in the mouse medial septum
Published in Brain Structure and Function (01-09-2019)“…The medial septal nucleus is one of the basal forebrain nuclei that projects cholinergic input to the hippocampus and cortex. Two of the hallmarks of…”
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12
Statins alter the hepatobiliary transport of unconjugated and conjugated bilirubin in sandwich-cultured rat hepatocytes
Published in Toxicology in vitro (01-09-2014)“…•We studied the modulation of the transport of bilirubin by statins in SCRH.•All statins studied except pravastatin inhibited the uptake of bilirubin.•The…”
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13
Recurrent seizure-like events are associated with coupled astroglial synchronization
Published in Frontiers in cellular neuroscience (18-06-2015)“…Increasing evidence suggest that astrocytes significantly modulate neuronal function at the level of the tripartite synapse both in physiological and…”
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14
Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity
Published in Current pharmaceutical design (01-12-2013)“…Here we have studied regulatory changes of µ-opioid receptors accompanying in vivo 14-methoxymetopon treatments of rats. Previously, this ligand has been shown…”
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15
Straightforward and effective synthesis of γ-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes
Published in Bioorganic & medicinal chemistry letters (15-01-2016)“…[Display omitted] Supply of major metabolites such as γ-aminobutyric acid (GABA), β-alanine and taurine is an essential instrument that shapes signalling,…”
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Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonists
Published in BioMed research international (01-01-2013)“…Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to…”
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17
Long-lasting, distinct changes in central opioid receptor and urinary bladder functions in models of schizophrenia in rats
Published in European journal of pharmacology (01-07-2011)“…Ketamine treatments and social isolation of rats reflect certain features of schizophrenia, among them altered pain sensitivity. To study the underlying…”
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Prolonged Incubation of Acute Neuronal Tissue for Electrophysiology and Calcium-imaging
Published in Journal of visualized experiments (15-02-2017)“…Acute neuronal tissue preparations, brain slices and retinal wholemount, can usually only be maintained for 6 - 8 h following dissection. This limits the…”
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19
Prolonged Incubation of Acute Neuronal Tissue for Electrophysiology and Calcium-imaging
Published in Journal of visualized experiments (15-02-2017)Get full text
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20
Calcium Imaging in Brain Tissue Slices
Published in Methods in molecular biology (Clifton, N.J.) (2025)“…Calcium imaging is a method that was first developed in the mid-1970s yet kept developing until current days to allow accurate measurement of free calcium ions…”
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