Search Results - "Keizer, P"
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Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics
Published in Science (American Association for the Advancement of Science) (29-07-2022)“…Our understanding of the physical principles organizing the genome in the nucleus is limited by the lack of tools to directly exert and measure forces on…”
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2
Hypothyroxinemia and TPO-Antibody Positivity Are Risk Factors for Premature Delivery: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-11-2013)“…Context: Premature delivery is an important risk factor for child mortality and psychiatric, metabolic, and cardiovascular disease later in life. In the…”
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3
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling
Published in Oncogene (28-04-2016)“…Melanoma is the most lethal form of skin cancer and successful treatment of metastatic melanoma remains challenging. BRAF/MEK inhibitors only show a temporary…”
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4
Quantitation of glucocorticoid receptor DNA-binding dynamics by single-molecule microscopy and FRAP
Published in PloS one (14-03-2014)“…Recent advances in live cell imaging have provided a wealth of data on the dynamics of transcription factors. However, a consistent quantitative description of…”
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Maternal Thyroid Hormone Parameters during Early Pregnancy and Birth Weight: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-01-2013)“…Context: Maternal hyperthyroidism during pregnancy is associated with an increased risk of low birth weight, predisposing to neonatal morbidity and mortality…”
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Maternal Thyroid Function during Early Pregnancy and Cognitive Functioning in Early Childhood: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-09-2010)“…Context: Thyroid hormones are essential for neurodevelopment from early pregnancy onward. Yet population-based data on the association between maternal thyroid…”
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7
Low Sidelobe Phased Array Pattern Synthesis With Compensation for Errors Due to Quantized Tapering
Published in IEEE transactions on antennas and propagation (01-12-2011)“…Recently, the iterative Fourier transform (IFT) method has been introduced for the synthesis of low sidelobe patterns for array antennas with periodic element…”
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8
Maternal Early Pregnancy and Newborn Thyroid Hormone Parameters: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-02-2012)“…Context: Abnormal maternal thyroid parameters are associated with adverse pregnancy outcomes, with consequences for both mother and child. Although various…”
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Maternal Early-Pregnancy Thyroid Function Is Associated With Subsequent Hypertensive Disorders of Pregnancy: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-12-2014)“…Context: Hypertensive disorders during pregnancy are associated with a wide range of maternal and fetal complications, and only a few risk factors are known…”
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10
Ethnic Differences in Maternal Thyroid Parameters during Pregnancy: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-09-2013)“…Context: Abnormal maternal thyroid function during pregnancy is associated with various complications. International guidelines advocate the use of…”
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11
Fast and Accurate Array Calibration Using a Synthetic Array Approach
Published in IEEE transactions on antennas and propagation (01-11-2011)“…A new method for the calibration of arrays is presented that allows the simultaneous calibration of N array elements. It comprises the measurement of the array…”
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12
Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes
Published in Frontiers in immunology (27-06-2018)“…The lectin pathway (LP) of complement activation depends on the activation of the MBL-associated serine proteases (MASPs) circulating in complex with…”
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13
Amplitude-Only Low Sidelobe Synthesis for Large Thinned Circular Array Antennas
Published in IEEE transactions on antennas and propagation (01-02-2012)“…This communication presents results for the low sidelobe synthesis using amplitude-only tapering applied on the turned ON elements of large circular thinned…”
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14
Women with high early pregnancy urinary iodine levels have an increased risk of hyperthyroid newborns: the population-based Generation R Study
Published in Clinical endocrinology (Oxford) (01-04-2014)“…Objective Iodine deficiency during pregnancy results in thyroid dysfunction and has been associated with adverse obstetric and foetal effects, leading to…”
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15
Depth-of-Focus Correction in Single-Molecule Data Allows Analysis of 3D Diffusion of the Glucocorticoid Receptor in the Nucleus
Published in PloS one (10-11-2015)“…Single-molecule imaging of proteins in a 2D environment like membranes has been frequently used to extract diffusive properties of multiple fractions of…”
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16
The High Prevalence of Functional Complement Defects Induced by Chemotherapy
Published in Frontiers in immunology (17-10-2016)“…To date, oncology patients are more dependent on non-cellular host defense against pathogens due to intensive (chemo)therapy-related bone marrow suppression…”
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17
Radical reactions of c60
Published in Science (American Association for the Advancement of Science) (22-11-1991)“…Photochemically generated benzyl radicals react with C(60) producing radical and nonradical adducts Rn C(60) (R = C(6)H(5)CH(2)) with n = 1 to at least 15. The…”
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18
Identification of the SAAT gene involved in strawberry flavor biogenesis by use of DNA microarrays
Published in The Plant cell (01-05-2000)“…Fruit flavor is a result of a complex mixture of numerous compounds. The formation of these compounds is closely correlated with the metabolic changes…”
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Cognitive Development in Congenital Hypothyroidism: Is Overtreatment a Greater Threat Than Undertreatment?
Published in The journal of clinical endocrinology and metabolism (01-11-2013)“…Background: Optimal treatment of children with congenital hypothyroidism (CHT) is still debated. Our objective was to evaluate whether early undertreatment…”
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Soluble Flt1 and Placental Growth Factor Are Novel Determinants of Newborn Thyroid (Dys)Function: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-09-2014)“…Context: Adequate thyroid hormone availability during fetal and early life is crucial for normal child growth and development. Fetal growth heavily depends on…”
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