Search Results - "Keivish, T"
-
1
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists
Published in Bioorganic & medicinal chemistry (01-06-2001)“…The novel amide linked Angiotensin II (ANG II) cyclic analogue cyclo(3, 5) -[Sar(1)-Lys(3)-Glu(5)-Ile(8)] ANG II (18) has been designed, synthesized and…”
Get full text
Journal Article -
2
Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges: Role of C-Terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists
Published in Bioorganic & medicinal chemistry letters (16-09-2002)“…The novel amide linked Angiotensin II (ANG II) cyclic analogues: γ,ε-cyclo(3, 5)-[Sar 1-Glu 3-Lys 5-Ile 8] ANG II (I) and γ, ε-cyclo(3, 5)-[Sar 1-Glu 3-Lys…”
Get full text
Journal Article