Search Results - "Keith Webber, R."

The Antagonists But Not Partial Agonists of Glucocorticoid Receptor Ligands Show Substantial Side Effect Dissociation by Hu, Xiao, Du, Sarah, Tunca, Cansu, Braden, Timothy, Long, Kelly R, Lee, Jamie, Webb, Elizabeth G, Dietz, Jessica D, Hummert, Susan, Rouw, Sharon, Hegde, Shridhar G, Webber, R. Keith, Obukowicz, Mark G

“…A synthetic glucocorticoid receptor (GR) ligand with the efficacy of a glucocorticoid, but without the accompanying side effects, would meet an unmet medical…”
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Inhibitors of human nitric oxide synthase isoforms with the carbamidine moiety as a common structural element by Moore, William M., Keith Webber, R., Fok, Kam F., Jerome, Gina M., Kornmeier, Christine M., Tjoeng, Foe S., Currie, Mark G.

“…Identification of potent and selective inhibitors of inducible nitric oxide synthase (NOS) is of great interest because of their therapeutic potential for…”
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L-N6-(1-Iminoethyl)lysine: A Selective Inhibitor of Inducible Nitric Oxide Synthase by Moore, William M., Webber, R. Keith, Jerome, Gina M., Tjoeng, Foe S., Misko, Thomas P., Currie, Mark G.

“…L-N6-(1-Iminoethyl)lysine (L-NIL) has been synthesized and is shown to be both a potent and selective inhibitor of mouse inducible nitric oxide synthase…”
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Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase by Connor, Jane R., Manning, Pamela T., Settle, Steven L., Moore, William M., Jerome, Gina M., Webber, R.Keith, Tjoeng, F.Siong, Currie, Mark G.

“…Adjuvant-induced arthritis is a model of chronic inflammation that exhibits several pathological changes similar to those occurring in rheumatoid arthritis, an…”
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3-Methyl-4H-[1,2,4]-oxadiazol-5-one: a versatile synthon for protecting monosubstituted acetamidines by Moormann, Alan E., Wang, Jane L., Palmquist, Katherine E., Promo, Michele A., Snyder, Jeffery S., Scholten, Jeffrey A., Massa, Mark A., Sikorski, James A., Webber, R. Keith

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3-Methyl-4 H-[1,2,4]-oxadiazol-5-one: a versatile synthon for protecting monosubstituted acetamidines by Moormann, Alan E., Wang, Jane L., Palmquist, Katherine E., Promo, Michele A., Snyder, Jeffery S., Scholten, Jeffrey A., Massa, Mark A., Sikorski, James A., Webber, R. Keith

“…The utilization of 3-methyl-4 H-[1,2,4]-oxadiazol-5-one as a versatile protected acetamidine is demonstrated through employment in a variety of synthetic…”
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2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms by Moore, William M, Webber, R. Keith, Fok, Kam F, Jerome, Gina M, Connor, Jane R, Manning, Pamela T, Wyatt, Pamela S, Misko, Thomas P, Tjoeng, Foe S, Currie, Mark G

“…A series of 2-iminoazaheterocycles have been prepared and shown to be potent inhibitors of human nitric oxide synthase (NOS) isoforms. This series includes…”
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Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms by Webber, R. Keith, Metz, Suzanne, Moore, William M, Connor, Jane R, Currie, Mark G, Fok, Kam F, Hagen, Timothy J, Hansen, Donald W, Jerome, Gina M, Manning, Pamela T, Pitzele, Barnett S, Toth, Mihaly V, Trivedi, Mahima, Zupec, Mark E, Tjoeng, F. Siong

“…A series of analogues of 2-iminopiperidine have been prepared and shown to be potent inhibitors of the human nitric oxide synthase (NOS) isoforms. Methyl…”
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