Search Results - "Keith C. Bible"

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma by Borad, Mitesh J, Champion, Mia D, Egan, Jan B, Liang, Winnie S, Fonseca, Rafael, Bryce, Alan H, McCullough, Ann E, Barrett, Michael T, Hunt, Katherine, Patel, Maitray D, Young, Scott W, Collins, Joseph M, Silva, Alvin C, Condjella, Rachel M, Block, Matthew, McWilliams, Robert R, Lazaridis, Konstantinos N, Klee, Eric W, Bible, Keith C, Harris, Pamela, Oliver, Gavin R, Bhavsar, Jaysheel D, Nair, Asha A, Middha, Sumit, Asmann, Yan, Kocher, Jean-Pierre, Schahl, Kimberly, Kipp, Benjamin R, Barr Fritcher, Emily G, Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Phillips, Lori, McDonald, Jackie, Adkins, Jonathan, Mastrian, Stephen D, Placek, Pamela, Watanabe, Aprill T, Lobello, Janine, Han, Haiyong, Von Hoff, Daniel, Craig, David W, Stewart, A Keith, Carpten, John D

“…Advanced cholangiocarcinoma continues to harbor a difficult prognosis and therapeutic options have been limited. During the course of a clinical trial of whole…”
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Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study by Bible, Keith C, Dr, Suman, Vera J, Prof, Molina, Julian R, MD, Smallridge, Robert C, Prof, Maples, William J, MD, Menefee, Michael E, MD, Rubin, Joseph, Prof, Sideras, Kostandinos, MD, Morris, John C, MD, McIver, Bryan, MB, Burton, Jill K, Webster, Kevin P, Bieber, Carolyn, Traynor, Anne M, MD, Flynn, Patrick J, MD, Goh, Boon Cher, MBBS, Tang, Hui, PhD, Ivy, Susan Percy, MD, Erlichman, Charles, Prof

“…Summary Background Chemotherapy has historically proven ineffective in advanced differentiated thyroid cancers, but the realisation that various tyrosine…”
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Diagnosis and Management of Anaplastic Thyroid Cancer by Chintakuntlawar, Ashish V., MBBS, PhD, Foote, Robert L., MD, Kasperbauer, Jan L., MD, Bible, Keith C., MD, PhD

“…Anaplastic thyroid cancer (ATC) is a devastating and usually incurable diagnosis. Clinical and pathologic diagnosis is best assessed at a tertiary center with…”
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Bone metastases in thyroid cancer by Iñiguez-Ariza, Nicole M., Bible, Keith C., Clarke, Bart L.

“…•Osseous metastases (OMs) occur in only 4% of all thyroid cancer patients but are associated with greatly increased morbidity and mortality.•OMs are about…”
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Advanced radioiodine-refractory differentiated thyroid cancer: the sodium iodide symporter and other emerging therapeutic targets by Spitzweg, Christine, Prof, Bible, Keith C, Prof, Hofbauer, Lorenz C, Prof, Morris, John C, Prof

“…Summary Approximately 30% of patients with advanced, metastatic differentiated thyroid cancer have radioiodine-refractory disease, based on decreased…”
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A Multiinstitutional Phase 2 Trial of Pazopanib Monotherapy in Advanced Anaplastic Thyroid Cancer by Bible, Keith C, Suman, Vera J, Menefee, Michael E, Smallridge, Robert C, Molina, Julian R, Maples, William J, Karlin, Nina J, Traynor, Anne M, Kumar, Priya, Goh, Boon Cher, Lim, Wan-Teck, Bossou, Ayoko R, Isham, Crescent R, Webster, Kevin P, Kukla, Andrea K, Bieber, Carolyn, Burton, Jill K, Harris, Pamela, Erlichman, Charles, the Mayo Phase 2 Consortium and Mayo Clinic Endocrine Malignances Disease Oriented Group

“…Context/Objectives: Pazopanib, an inhibitor of kinases including vascular endothelial growth factor receptor, demonstrated impressive activity in progressive…”
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Immunotherapy in Anaplastic Thyroid Cancer: Much Yet to Be Learned by Bible, Keith C.

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Enhanced survival in locoregionally confined anaplastic thyroid carcinoma: a single-institution experience using aggressive multimodal therapy by Foote, Robert L, Molina, Julian R, Kasperbauer, Jan L, Lloyd, Ricardo V, McIver, Bryan, Morris, John C, Grant, Clive S, Thompson, Geoffrey B, Richards, Melanie L, Hay, Ian D, Smallridge, Robert C, Bible, Keith C

“…Historical outcomes in anaplastic thyroid carcinoma (ATC) are poor, with a median survival of only 5 months and <20% of patients surviving 1 year from…”
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Combined lenvatinib and pembrolizumab as salvage therapy in advanced adrenal cortical carcinoma by Bedrose, Sara, Miller, Kevin Charles, Altameemi, Lina, Ali, Mohamed S, Nassar, Sameh, Garg, Naveen, Daher, Marilyne, Eaton, Keith D, Yorio, Jeffrey Thomas, Daniel, Davey B, Campbell, Matthew, Bible, Keith C, Ryder, Mabel, Chintakuntlawar, Ashish V, Amir Habra, Mouhammed

“…BackgroundThere is no effective systemic therapy for metastatic adrenal cortical carcinoma (ACC) after failure of platinum-based chemotherapy. The efficacies…”
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Pazopanib enhances paclitaxel-induced mitotic catastrophe in anaplastic thyroid cancer by Isham, Crescent R, Bossou, Ayoko R, Negron, Vivian, Fisher, Kelly E, Kumar, Rakesh, Marlow, Laura, Lingle, Wilma L, Smallridge, Robert C, Sherman, Eric J, Suman, Vera J, Copland, John A, Bible, Keith C

“…Anaplastic thyroid cancer (ATC) has perhaps the worst prognosis of any cancer, with a median survival of only about 5 months regardless of stage. Pazopanib…”
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The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase by Tibodeau, Jennifer D, Benson, Linda M, Isham, Crescent R, Owen, Whyte G, Bible, Keith C

“…We recently reported that the antineoplastic thiodioxopiperazine natural product chaetocin potently induces cellular oxidative stress, thus selectively killing…”
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External beam radiation therapy for advanced/unresectable malignant paraganglioma and pheochromocytoma by Breen, William, Bancos, Irina, Young, William F., Bible, Keith C., Laack, Nadia N., Foote, Robert L., Hallemeier, Christopher L.

“…To evaluate the role of external beam radiation therapy (EBRT) for treatment of malignant paraganglioma (PGL) and pheochromocytoma (PCC). A retrospective…”
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Operative intervention for recurrent adrenocortical cancer by Dy, Benzon M., MD, Wise, Kevin B., MD, Richards, Melanie L., MD, Young, William F., MD, Grant, Clive S., MD, Bible, Keith C., MD, PhD, Rosedahl, Jordan, BS, Harmsen, William S., MS, Farley, David R., MD, Thompson, Geoffrey B., MD

“…Introduction Adrenocortical cancer (ACC) recurs despite apparent complete resection. We examined the survival and palliative benefit of resection for recurrent…”
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Evolving molecularly targeted therapies for advanced-stage thyroid cancers by Bible, Keith C., Ryder, Mabel

“…Key Points Advances in understanding the genomic and functional alterations contributing to the pathogenesis of thyroid cancers have opened new therapeutic…”
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Development and Characterization of a Differentiated Thyroid Cancer Cell Line Resistant to VEGFR-Targeted Kinase Inhibitors by Isham, Crescent R, Netzel, Brian C, Bossou, Ayoko R, Milosevic, Dragana, Cradic, Kendall W, Grebe, Stefan K, Bible, Keith C

“…Background: Vascular endothelial growth factor-targeted kinase inhibitors have emerged as highly promising therapies for radioiodine-refractory metastatic…”
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2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer by Bible, Keith C, Kebebew, Electron, Brierley, James, Brito, Juan P, Cabanillas, Maria E, Clark, Jr, Thomas J, Di Cristofano, Antonio, Foote, Robert, Giordano, Thomas, Kasperbauer, Jan, Newbold, Kate, Nikiforov, Yuri E, Randolph, Gregory, Rosenthal, M Sara, Sawka, Anna M, Shah, Manisha, Shaha, Ashok, Smallridge, Robert, Wong-Clark, Carol K

“…Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Since the guidelines for the management of ATC by the American Thyroid…”
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2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer by Haugen, Bryan R, Alexander, Erik K, Bible, Keith C, Doherty, Gerard M, Mandel, Susan J, Nikiforov, Yuri E, Pacini, Furio, Randolph, Gregory W, Sawka, Anna M, Schlumberger, Martin, Schuff, Kathryn G, Sherman, Steven I, Sosa, Julie Ann, Steward, David L, Tuttle, R Michael, Wartofsky, Leonard

“…Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's…”
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Open-Label, Single-Arm, Multicenter, Phase II Trial of Lenvatinib for the Treatment of Patients With Anaplastic Thyroid Cancer by Wirth, Lori J, Brose, Marcia S, Sherman, Eric J, Licitra, Lisa, Schlumberger, Martin, Sherman, Steven I, Bible, Keith C, Robinson, Bruce, Rodien, Patrice, Godbert, Yann, De La Fouchardiere, Christelle, Newbold, Kate, Nutting, Christopher, Misir, Soamnauth, Xie, Ran, Almonte, Ana, Ye, Weifei, Cabanillas, Maria E

“…Anaplastic thyroid cancer (ATC), an aggressive malignancy, is associated with a poor prognosis and an unmet need for effective treatment, especially for…”
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American Thyroid Association Guidelines on the Management of Thyroid Nodules and Differentiated Thyroid Cancer Task Force Review and Recommendation on the Proposed Renaming of Encapsulated Follicular Variant Papillary Thyroid Carcinoma Without Invasion to Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features by Haugen, Bryan R, Sawka, Anna M, Alexander, Erik K, Bible, Keith C, Caturegli, Patrizio, Doherty, Gerard M, Mandel, Susan J, Morris, John C, Nassar, Aziza, Pacini, Furio, Schlumberger, Martin, Schuff, Kathryn, Sherman, Steven I, Somerset, Hilary, Sosa, Julie Ann, Steward, David L, Wartofsky, Leonard, Williams, Michelle D

“…American Thyroid Association (ATA) leadership asked the ATA Thyroid Nodules and Differentiated Thyroid Cancer Guidelines Task Force to review, comment on, and…”
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Inhibition of Mitochondrial Respiration as a Source of Adaphostin-induced Reactive Oxygen Species and Cytotoxicity by Le, Son B., Hailer, M. Katie, Buhrow, Sarah, Wang, Qi, Flatten, Karen, Pediaditakis, Peter, Bible, Keith C., Lewis, Lionel D., Sausville, Edward A., Pang, Yuan-Ping, Ames, Matthew M., Lemasters, John J., Holmuhamedov, Ekhson L., Kaufmann, Scott H.

“…Adaphostin is a dihydroquinone derivative that is undergoing extensive preclinical testing as a potential anticancer drug. Previous studies have suggested that…”
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